5CZ2
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![BU of 5cz2 by Molmil](/molmil-images/mine/5cz2) | Crystal structure of a two-domain fragment of MMTV integrase | Descriptor: | MAGNESIUM ION, Pol polyprotein, ZINC ION | Authors: | Cook, N, Ballandras-Colas, A, Engelman, A, Cherepanov, P. | Deposit date: | 2015-07-31 | Release date: | 2016-02-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function. Nature, 530, 2016
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5CZ1
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![BU of 5cz1 by Molmil](/molmil-images/mine/5cz1) | |
6GX9
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![BU of 6gx9 by Molmil](/molmil-images/mine/6gx9) | Crystal structure of the TNPO3 - CPSF6 RSLD complex | Descriptor: | BENZAMIDINE, BICINE, Cleavage and polyadenylation specificity factor subunit 6, ... | Authors: | Cherepanov, P, Cook, N. | Deposit date: | 2018-06-26 | Release date: | 2019-03-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Differential role for phosphorylation in alternative polyadenylation function versus nuclear import of SR-like protein CPSF6. Nucleic Acids Res., 47, 2019
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1W5T
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![BU of 1w5t by Molmil](/molmil-images/mine/1w5t) | Structure of the Aeropyrum Pernix ORC2 protein (ADPNP-ADP complexes) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ORC2, ... | Authors: | Singleton, M.R, Morales, R, Grainge, I, Cook, N, Isupov, M.N, Wigley, D.B. | Deposit date: | 2004-08-09 | Release date: | 2004-10-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Conformational Changes Induced by Nucleotide Binding in Cdc6/Orc from Aeropyrum Pernix J.Mol.Biol., 343, 2004
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1W5S
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![BU of 1w5s by Molmil](/molmil-images/mine/1w5s) | Structure of the Aeropyrum Pernix ORC2 protein (ADP form) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORC2, SULFATE ION | Authors: | Singleton, M.R, Morales, R, Grainge, I, Cook, N, Isupov, M.N, Wigley, D.B. | Deposit date: | 2004-08-09 | Release date: | 2004-10-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Conformational Changes Induced by Nucleotide Binding in Cdc6/Orc from Aeropyrum Pernix J.Mol.Biol., 343, 2004
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2UV1
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![BU of 2uv1 by Molmil](/molmil-images/mine/2uv1) | |
2UUZ
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![BU of 2uuz by Molmil](/molmil-images/mine/2uuz) | |
3E1S
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![BU of 3e1s by Molmil](/molmil-images/mine/3e1s) | Structure of an N-terminal truncation of Deinococcus radiodurans RecD2 | Descriptor: | Exodeoxyribonuclease V, subunit RecD | Authors: | Saikrishnan, K, Griffiths, S.P, Cook, N, Court, R, Wigley, D.B. | Deposit date: | 2008-08-04 | Release date: | 2008-08-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | DNA binding to RecD: role of the 1B domain in SF1B helicase activity. Embo J., 27, 2008
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2CHV
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![BU of 2chv by Molmil](/molmil-images/mine/2chv) | Replication Factor C ADPNP complex | Descriptor: | REPLICATION FACTOR C SMALL SUBUNIT | Authors: | Seybert, A, Singleton, M.R, Cook, N, Hall, D.R, Wigley, D.B. | Deposit date: | 2006-03-16 | Release date: | 2006-06-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Communication between Subunits within an Archaeal Clamp-Loader Complex. Embo J., 25, 2006
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2CHQ
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![BU of 2chq by Molmil](/molmil-images/mine/2chq) | Replication Factor C ADPNP complex | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, REPLICATION FACTOR C SMALL SUBUNIT | Authors: | Seybert, A, Singleton, M.R, Cook, N, Hall, D.R, Wigley, D.B. | Deposit date: | 2006-03-16 | Release date: | 2006-06-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Communication between Subunits within an Archaeal Clamp-Loader Complex. Embo J., 25, 2006
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2CHG
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![BU of 2chg by Molmil](/molmil-images/mine/2chg) | Replication Factor C domains 1 and 2 | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, REPLICATION FACTOR C SMALL SUBUNIT | Authors: | Seybert, A, Singleton, M.R, Cook, N, Hall, D.R, Wigley, D.B. | Deposit date: | 2006-03-14 | Release date: | 2006-06-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Communication between Subunits within an Archaeal Clamp-Loader Complex. Embo J., 25, 2006
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3GPL
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![BU of 3gpl by Molmil](/molmil-images/mine/3gpl) | Crystal structure of the ternary complex of RecD2 with DNA and ADPNP | Descriptor: | 5'-D(*T*TP*TP*TP*TP*TP*TP*T)-3', Exodeoxyribonuclease V, subunit RecD, ... | Authors: | Saikrishnan, K, Cook, N, Wigley, D.B. | Deposit date: | 2009-03-23 | Release date: | 2009-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mechanistic basis of 5'-3' translocation in SF1B helicases. Cell(Cambridge,Mass.), 137, 2009
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3GP8
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![BU of 3gp8 by Molmil](/molmil-images/mine/3gp8) | Crystal structure of the binary complex of RecD2 with DNA | Descriptor: | 5'-D(*TP*TP*TP*TP*TP*T*TP*TP*TP*TP*TP*TP*TP*T)-3', Exodeoxyribonuclease V, subunit RecD, ... | Authors: | Saikrishnan, K, Cook, N, Wigley, D.B. | Deposit date: | 2009-03-23 | Release date: | 2009-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mechanistic basis of 5'-3' translocation in SF1B helicases. Cell(Cambridge,Mass.), 137, 2009
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6RWO
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![BU of 6rwo by Molmil](/molmil-images/mine/6rwo) | SIVrcm intasome (Q148H/G140S) in complex with bictegravir | Descriptor: | Bictegravir, CHLORIDE ION, DNA (5'-D(*AP*AP*CP*TP*GP*GP*TP*AP*GP*AP*GP*AP*TP*TP*TP*TP*TP*CP*TP*TP*AP*GP*C)-3'), ... | Authors: | Cherepanov, P, Nans, A, Cook, N. | Deposit date: | 2019-06-05 | Release date: | 2020-02-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Structural basis of second-generation HIV integrase inhibitor action and viral resistance. Science, 367, 2020
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6RWN
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![BU of 6rwn by Molmil](/molmil-images/mine/6rwn) | SIVrcm intasome in complex with dolutegravir | Descriptor: | (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, CHLORIDE ION, DNA (5'-D(*AP*AP*CP*TP*GP*GP*TP*AP*GP*AP*GP*AP*TP*TP*TP*TP*TP*CP*TP*TP*AP*GP*C)-3'), ... | Authors: | Cherepanov, P, Nans, A, Cook, N. | Deposit date: | 2019-06-05 | Release date: | 2020-02-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of second-generation HIV integrase inhibitor action and viral resistance. Science, 367, 2020
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6RWM
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![BU of 6rwm by Molmil](/molmil-images/mine/6rwm) | SIVrcm intasome in complex with bictegravir | Descriptor: | Bictegravir, CHLORIDE ION, DNA (5'-D(*AP*AP*CP*TP*GP*GP*TP*AP*GP*AP*GP*AP*TP*TP*TP*TP*TP*CP*TP*TP*AP*GP*C)-3'), ... | Authors: | Cherepanov, P, Nans, A, Cook, N. | Deposit date: | 2019-06-05 | Release date: | 2020-02-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.81 Å) | Cite: | Structural basis of second-generation HIV integrase inhibitor action and viral resistance. Science, 367, 2020
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6RWL
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![BU of 6rwl by Molmil](/molmil-images/mine/6rwl) | SIVrcm intasome | Descriptor: | DNA (5'-D(*AP*AP*CP*TP*GP*GP*TP*AP*GP*AP*GP*AP*TP*TP*TP*TP*TP*CP*TP*TP*AP*GP*C)-3'), DNA (5'-D(P*GP*CP*TP*AP*AP*GP*AP*AP*AP*AP*AP*TP*CP*TP*CP*TP*AP*CP*CP*A)-3'), Pol protein, ... | Authors: | Cherepanov, P, Nans, A, Cook, N. | Deposit date: | 2019-06-05 | Release date: | 2020-02-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Structural basis of second-generation HIV integrase inhibitor action and viral resistance. Science, 367, 2020
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