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PDB: 32 件

6SV2
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Human prion protein (PrP) fragment 119-231 (G127V M129 variant) complexed to ICSM 18 (anti-Prp therapeutic antibody) Fab fragment
分子名称: ICSM 18-ANTI-PRP THERAPEUTIC FAB HEAVY CHAIN, ICSM 18-ANTI-PRP THERAPEUTIC FAB LIGHT CHAIN, Major prion protein, ...
著者Conners, R.
登録日2019-09-17
公開日2020-07-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural effects of the highly protective V127 polymorphism on human prion protein.
Commun Biol, 3, 2020
6SUZ
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BU of 6suz by Molmil
Human prion protein (PrP) fragment 119-231 (G127V V129 variant) complexed to ICSM 18 (anti-Prp therapeutic antibody) Fab fragment
分子名称: ICSM 18-ANTI-PRP THERAPEUTIC FAB HEAVY CHAIN, ICSM 18-ANTI-PRP THERAPEUTIC FAB LIGHT CHAIN, Major prion protein, ...
著者Conners, R.
登録日2019-09-17
公開日2020-08-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural effects of the highly protective V127 polymorphism on human prion protein.
Commun Biol, 3, 2020
7OFH
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BU of 7ofh by Molmil
CryoEM structure of the outer membrane secretin pore pIV from the f1 filamentous bacteriophage.
分子名称: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Virion export protein
著者Conners, R, Gold, V.A.M.
登録日2021-05-05
公開日2021-11-03
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage.
Nat Commun, 12, 2021
3NTN
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BU of 3ntn by Molmil
Crystal Structure of UspA1 head and neck domain from Moraxella catarrhalis
分子名称: CHLORIDE ION, NICKEL (II) ION, SULFATE ION, ...
著者Conners, R, Zaccai, N, Agnew, C, Burton, N, Brady, R.L.
登録日2010-07-05
公開日2011-07-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Correlation of in situ mechanosensitive responses of the Moraxella catarrhalis adhesin UspA1 with fibronectin and receptor CEACAM1 binding.
Proc.Natl.Acad.Sci.USA, 108, 2011
2CMY
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BU of 2cmy by Molmil
Crystal complex between bovine trypsin and Veronica hederifolia trypsin inhibitor
分子名称: CALCIUM ION, CATIONIC TRYPSIN, GLYCEROL, ...
著者Conners, R, Yardley, J.L, Konarev, A, Shewry, P, Brady, R.L.
登録日2006-05-16
公開日2007-05-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献An Unusual Helix-Turn-Helix Protease Inhibitory Motif in a Novel Trypsin Inhibitor from Seeds of Veronica (Veronica Hederifolia L.).
J.Biol.Chem., 282, 2007
8B3Q
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BU of 8b3q by Molmil
CryoEM structure of the central filamentous region of the f1 filamentous bacteriophage, consisting of the major capsid protein pVIII
分子名称: Capsid protein G8P
著者Conners, R, McLaren, M, Gold, V.A.M.
登録日2022-09-16
公開日2023-05-24
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献Cryo-electron microscopy of the f1 filamentous phage reveals insights into viral infection and assembly.
Nat Commun, 14, 2023
8B3P
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CryoEM structure of the round tip (proteins pVII/pVIII/pIX) from the f1 filamentous bacteriophage
分子名称: Capsid protein G8P, Tail virion protein G7P, Tail virion protein G9P
著者Conners, R, McLaren, M, Gold, V.A.M.
登録日2022-09-16
公開日2023-05-24
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Cryo-electron microscopy of the f1 filamentous phage reveals insights into viral infection and assembly.
Nat Commun, 14, 2023
8B3O
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BU of 8b3o by Molmil
CryoEM structure of the pointy tip (proteins pIII/pVI/pVIII) from the f1 filamentous bacteriophage
分子名称: Attachment protein G3P, Capsid protein G8P, Head virion protein G6P
著者Conners, R, McLaren, M, Gold, V.A.M.
登録日2022-09-16
公開日2023-05-24
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Cryo-electron microscopy of the f1 filamentous phage reveals insights into viral infection and assembly.
Nat Commun, 14, 2023
2PLX
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BU of 2plx by Molmil
Trypsin complexed to a synthetic peptide from Veronica hederifolia
分子名称: CALCIUM ION, CITRATE ANION, Cationic trypsin, ...
著者Conners, R, Brady, R.L.
登録日2007-04-20
公開日2007-08-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献An Unusual Helix-Turn-Helix Protease Inhibitory Motif in a Novel Trypsin Inhibitor from Seeds of Veronica (Veronica hederifolia L.)
J.Biol.Chem., 282, 2007
2QIH
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BU of 2qih by Molmil
Crystal structure of 527-665 fragment of UspA1 protein from Moraxella catarrhalis
分子名称: CHLORIDE ION, PHOSPHATE ION, protein UspA1
著者Conners, R, Brady, R.L.
登録日2007-07-04
公開日2008-05-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.897 Å)
主引用文献The Moraxella adhesin UspA1 binds to its human CEACAM1 receptor by a deformable trimeric coiled-coil.
Embo J., 27, 2008
2A5C
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BU of 2a5c by Molmil
Structure of Avidin in complex with the ligand 8-oxodeoxyadenosine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 8-OXODEOXYADENOSINE, Avidin
著者Conners, R, Hooley, E, Thomas, S, Brady, R.L.
登録日2005-06-30
公開日2006-05-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Recognition of oxidatively modified bases within the biotin-binding site of avidin.
J.Mol.Biol., 357, 2006
2A8G
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Structure of Avidin in complex with the ligand deoxyguanosine
分子名称: 2'-DEOXY-GUANOSINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Avidin
著者Conners, R, Hooley, E, Thomas, S, Brady, R.L.
登録日2005-07-08
公開日2006-05-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Recognition of oxidatively modified bases within the biotin-binding site of avidin.
J.Mol.Biol., 357, 2006
1U5A
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BU of 1u5a by Molmil
Plasmodium falciparum lactate dehydrogenase complexed with 3,5-dihydroxy-2-naphthoic acid
分子名称: 3,7-DIHYDROXY-2-NAPHTHOIC ACID, L-lactate dehydrogenase
著者Conners, R, Cameron, A, Read, J, Schambach, F, Sessions, R.B, Brady, R.L.
登録日2004-07-27
公開日2005-06-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase.
Mol.Biochem.Parasitol., 142, 2005
1U4S
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BU of 1u4s by Molmil
Plasmodium falciparum lactate dehydrogenase complexed with 2,6-naphthalenedisulphonic acid
分子名称: L-lactate dehydrogenase, NAPHTHALENE-2,6-DISULFONIC ACID
著者Conners, R, Cameron, A, Read, J, Schambach, F, Sessions, R.B, Brady, R.L.
登録日2004-07-26
公開日2005-06-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase.
Mol.Biochem.Parasitol., 142, 2005
1U4O
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BU of 1u4o by Molmil
Plasmodium falciparum lactate dehydrogenase complexed with 2,6-naphthalenedicarboxylic acid
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2,6-DICARBOXYNAPHTHALENE, L-lactate dehydrogenase
著者Conners, R, Cameron, A, Read, J, Schambach, F, Sessions, R.B, Brady, R.L.
登録日2004-07-26
公開日2005-06-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase.
Mol.Biochem.Parasitol., 142, 2005
1U5C
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BU of 1u5c by Molmil
Plasmodium falciparum lactate dehydrogenase complexed with 3,7-dihydroxynaphthalene-2-carboxylic acid and NAD+
分子名称: 3,7-DIHYDROXY-2-NAPHTHOIC ACID, L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Conners, R, Cameron, A, Read, J, Schambach, F, Sessions, R.B, Brady, R.L.
登録日2004-07-27
公開日2005-06-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase.
Mol.Biochem.Parasitol., 142, 2005
1XIV
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BU of 1xiv by Molmil
Plasmodium falciparum lactate dehydrogenase complexed with 2-({4-chloro-[hydroxy(methoxy)methyl]cyclohexyl}amino)ethane-1,1,2-triol
分子名称: 2-({4-CHLORO-2-[HYDROXY(METHOXY)METHYL]CYCLOHEXYL}AMINO)ETHANE-1,1,2-TRIOL, GLYCEROL, L-lactate dehydrogenase
著者Conners, R, Cameron, A, Read, J.A, Schambach, F, Sessions, R.B, Brady, R.L.
登録日2004-09-22
公開日2005-06-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase
MOL.BIOCHEM.PARASITOL., 142, 2005
2A5B
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BU of 2a5b by Molmil
Avidin complexed with 8-oxodeoxyguanosine
分子名称: 2'-DEOXY-8-OXOGUANOSINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Avidin
著者Conners, R, Hooley, E, Thomas, S, Brady, R.L.
登録日2005-06-30
公開日2006-05-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Recognition of oxidatively modified bases within the biotin-binding site of avidin.
J.Mol.Biol., 357, 2006
2GCG
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BU of 2gcg by Molmil
Ternary Crystal Structure of Human Glyoxylate Reductase/Hydroxypyruvate Reductase
分子名称: (2R)-2,3-DIHYDROXYPROPANOIC ACID, Glyoxylate reductase/hydroxypyruvate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Booth, M.P.S, Conners, R, Rumsby, G, Brady, R.L.
登録日2006-03-14
公開日2006-07-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of substrate specificity in human glyoxylate reductase/hydroxypyruvate reductase
J.Mol.Biol., 360, 2006
7QCA
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Spraguea lophii ribosome
分子名称: 40S Ribosomal protein S19, 40S ribosomal protein S0, 40S ribosomal protein S10, ...
著者Gil Diez, P, McLaren, M, Isupov, M.N, Daum, B, Conners, R, Williams, B.
登録日2021-11-22
公開日2022-11-30
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献CryoEM reveals that ribosomes in microsporidian spores are locked in a dimeric hibernating state
Nat Microbiol, 2023
3PR7
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BU of 3pr7 by Molmil
Multi-functional and mechanosensitive receptor binding activity of the Moraxella catarrhalis adhesin UspA1
分子名称: UspA1
著者Agnew, C.R.J, Zaccai, N.R, Conners, R, Brady, R.L.
登録日2010-11-29
公開日2011-09-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Correlation of in situ mechanosensitive responses of the Moraxella catarrhalis adhesin UspA1 with fibronectin and receptor CEACAM1 binding.
Proc.Natl.Acad.Sci.USA, 108, 2011
2WWR
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BU of 2wwr by Molmil
Crystal Structure of Human Glyoxylate Reductase Hydroxypyruvate Reductase
分子名称: GLYOXYLATE REDUCTASE/HYDROXYPYRUVATE REDUCTASE, MAGNESIUM ION
著者Booth, M.P.S, Conners, R, Rumsby, G, Brady, R.L.
登録日2009-10-26
公開日2010-10-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Structural Basis of Substrate Specificity in Human Glyoxylate Reductase/Hydroxypyruvate Reductase.
J.Mol.Biol., 360, 2006
3IT5
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BU of 3it5 by Molmil
Crystal Structure of the LasA Virulence Factor from Pseudomonas aeruginosa
分子名称: Protease lasA, ZINC ION
著者Spencer, J, Murphy, L.M, Conners, R, Sessions, R.B, Gamblin, S.J.
登録日2009-08-27
公開日2009-11-17
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the LasA virulence factor from Pseudomonas aeruginosa: substrate specificity and mechanism of M23 metallopeptidases.
J.Mol.Biol., 396, 2010
3IT7
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Crystal Structure of the LasA virulence factor from Pseudomonas aeruginosa
分子名称: GLYCEROL, L(+)-TARTARIC ACID, Protease lasA, ...
著者Spencer, J, Murphy, L.M, Conners, R, Sessions, R.B, Gamblin, S.J.
登録日2009-08-27
公開日2009-11-17
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Crystal structure of the LasA virulence factor from Pseudomonas aeruginosa: substrate specificity and mechanism of M23 metallopeptidases.
J.Mol.Biol., 396, 2010
8P60
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BU of 8p60 by Molmil
Spraguea lophii ribosome dimer
分子名称: 40S Ribosomal protein S19, 40S ribosomal protein S0, 40S ribosomal protein S1, ...
著者Gil Diez, P, McLaren, M, Isupov, M.N, Daum, B, Conners, R, Williams, B.
登録日2023-05-24
公開日2023-06-21
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (14.3 Å)
主引用文献CryoEM reveals that ribosomes in microsporidian spores are locked in a dimeric hibernating state.
Nat Microbiol, 8, 2023

 

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