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PDB: 33 results

2RFE
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BU of 2rfe by Molmil
Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide
Descriptor: ERBB receptor feedback inhibitor 1, Epidermal growth factor receptor
Authors:Zhang, X, Pickin, K.A, Bose, R, Jura, N, Cole, P.A, Kuriyan, J.
Deposit date:2007-09-28
Release date:2007-12-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface.
Nature, 450, 2007
2GS2
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BU of 2gs2 by Molmil
Crystal Structure of the active EGFR kinase domain
Descriptor: Epidermal growth factor receptor
Authors:Zhang, X, Gureasko, J, Shen, K, Cole, P.A, Kuriyan, J.
Deposit date:2006-04-25
Release date:2006-06-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor.
Cell(Cambridge,Mass.), 125, 2006
2RFD
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BU of 2rfd by Molmil
Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide
Descriptor: ERBB receptor feedback inhibitor 1, Epidermal growth factor receptor, SULFATE ION
Authors:Zhang, X, Pickin, K.A, Bose, R, Jura, N, Cole, P.A, Kuriyan, J.
Deposit date:2007-09-28
Release date:2007-12-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface.
Nature, 450, 2007
2GS6
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BU of 2gs6 by Molmil
Crystal Structure of the active EGFR kinase domain in complex with an ATP analog-peptide conjugate
Descriptor: CHLORIDE ION, Epidermal growth factor receptor, Peptide, ...
Authors:Zhang, X, Gureasko, J, Shen, K, Cole, P.A, Kuriyan, J.
Deposit date:2006-04-25
Release date:2006-06-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor
Cell(Cambridge,Mass.), 125, 2006
4PGF
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BU of 4pgf by Molmil
The structure of mono-acetylated SAHH
Descriptor: ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Kavran, J.M, Wang, Y, Cole, P.A, Leahy, D.J.
Deposit date:2014-05-01
Release date:2014-10-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Regulation of s-adenosylhomocysteine hydrolase by lysine acetylation.
J.Biol.Chem., 289, 2014
2UXN
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BU of 2uxn by Molmil
Structural Basis of Histone Demethylation by LSD1 Revealed by Suicide Inactivation
Descriptor: CHLORIDE ION, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, GLYCEROL, ...
Authors:Yang, M, Culhane, J.C, Szewczuk, L.M, Gocke, C.B, Brautigam, C.A, Tomchick, D.R, Machius, M, Cole, P.A, Yu, H.
Deposit date:2007-03-28
Release date:2007-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Structural Basis of Histone Demethylation by Lsd1 Revealed by Suicide Inactivation.
Nat.Struct.Mol.Biol., 14, 2007
4PFJ
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BU of 4pfj by Molmil
The structure of bi-acetylated SAHH
Descriptor: ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Kavran, J.M, Wang, Y, Cole, P.A, Leahy, D.J.
Deposit date:2014-04-29
Release date:2014-10-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Regulation of s-adenosylhomocysteine hydrolase by lysine acetylation.
J.Biol.Chem., 289, 2014
2RF9
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BU of 2rf9 by Molmil
Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide
Descriptor: ERBB receptor feedback inhibitor 1, Epidermal growth factor receptor
Authors:Zhang, X, Pickin, K.A, Bose, R, Jura, N, Cole, P.A, Kuriyan, J.
Deposit date:2007-09-28
Release date:2007-12-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface.
Nature, 450, 2007
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數據於2024-08-28公開中

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