2LJV
| Solution structure of Rhodostomin G50L mutant | Descriptor: | Disintegrin rhodostomin | Authors: | Chuang, W, Shiu, J, Chen, C, Chen, Y, Chang, Y, Huang, C. | Deposit date: | 2011-09-29 | Release date: | 2012-10-03 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Design of Integrin AlphaVbeta3-Specific Disintegrin for Cancer Therapy To be Published
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1W2I
| Crystal structuore of acylphosphatase from Pyrococcus horikoshii complexed with formate | Descriptor: | ACYLPHOSPHATASE, FORMIC ACID | Authors: | Cheung, Y.Y, Lam, S.Y, Chu, W.K, Allen, M.D, Bycroft, M, Wong, K.B. | Deposit date: | 2004-07-06 | Release date: | 2004-08-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal Structure of a Hyperthermophilic Archaeal Acylphosphatase from Pyrococcus Horikoshii-Structural Insights Into Enzymatic Catalysis, Thermostability, and Dimerization Biochemistry, 44, 2005
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209D
| Structural, physical and biological characteristics of RNA:DNA binding agent N8-actinomycin D | Descriptor: | DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3'), N8-ACTINOMYCIN D | Authors: | Shinomiya, M, Chu, W, Carlson, R.G, Weaver, R.F, Takusagawa, F. | Deposit date: | 1995-05-01 | Release date: | 1995-10-15 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural, Physical, and Biological Characteristics of RNA.DNA Binding Agent N8-Actinomycin D. Biochemistry, 34, 1995
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2D55
| Structural, physical and biological characteristics of RNA.DNA binding agent N8-actinomycin D | Descriptor: | ACTINOMYCIN D, DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3') | Authors: | Shinomiya, M, Chu, W, Carlson, R.G, Weaver, R.F, Takusagawa, F. | Deposit date: | 1995-05-01 | Release date: | 1995-10-15 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structure of the 2:1 Complex between D(Gaagcttc) and the Anticancer Drug Actinomycin D. J.Mol.Biol., 225, 1992
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1W56
| Stepwise introduction of zinc binding site into porphobilinogen synthase of Pseudomonas aeruginosa (mutations A129C and D131C) | Descriptor: | DELTA-AMINOLEVULINIC ACID DEHYDRATASE, FORMIC ACID, MAGNESIUM ION, ... | Authors: | Frere, F, Reents, H, Schubert, W.-D, Heinz, D.W, Jahn, D. | Deposit date: | 2004-08-05 | Release date: | 2005-01-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro J.Mol.Biol., 345, 2005
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1W5O
| Stepwise introduction of zinc binding site into porphobilinogen synthase of Pseudomonas aeruginosa (mutations A129C, D131C and D139C) | Descriptor: | DELTA-AMINOLEVULINIC ACID DEHYDRATASE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Frere, F, Reents, H, Schubert, W.-D, Heinz, D.W, Jahn, D. | Deposit date: | 2004-08-09 | Release date: | 2005-01-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro J.Mol.Biol., 345, 2005
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7X4S
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7X4V
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7X4Z
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5EFS
| The crystal structure of human kynurenine aminotransferase II | Descriptor: | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | Authors: | Nematollahi, A, Sun, G, Kwan, A, Harrop, S.J, Hanrahan, J.R, Nadvi, N.A, Church, W.B. | Deposit date: | 2015-10-26 | Release date: | 2015-11-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.82503 Å) | Cite: | The crystal structure of human kynurenine aminotransferase II To Be Published
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4U5M
| Structure of a left-handed DNA G-quadruplex | Descriptor: | DNA (28-MER), MAGNESIUM ION, POTASSIUM ION | Authors: | Schmitt, E, Mechulam, Y, Phan, A.T, Brahim, H, Chung, W.J, Lim, K.W. | Deposit date: | 2014-07-25 | Release date: | 2015-02-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of a left-handed DNA G-quadruplex. Proc.Natl.Acad.Sci.USA, 112, 2015
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2BWO
| 5-Aminolevulinate Synthase from Rhodobacter capsulatus in complex with succinyl-CoA | Descriptor: | 5-AMINOLEVULINATE SYNTHASE, PYRIDOXAL-5'-PHOSPHATE, SUCCINYL-COENZYME A | Authors: | Astner, I, Schulze, J.O, van den Heuvel, J.J, Jahn, D, Schubert, W.-D, Heinz, D.W. | Deposit date: | 2005-07-15 | Release date: | 2005-09-27 | Last modified: | 2015-12-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of 5-Aminolevulinate Synthase, the First Enzyme of Heme Biosynthesis, and its Link to Xlsa in Humans. Embo J., 24, 2005
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2CFB
| Glutamate-1-semialdehyde 2,1-Aminomutase from Thermosynechococcus elongatus | Descriptor: | (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE | Authors: | Schulze, J.O, Schubert, W.-D, Moser, J, Jahn, D, Heinz, D.W. | Deposit date: | 2006-02-17 | Release date: | 2006-03-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Evolutionary Relationship between Initial Enzymes of Tetrapyrrole Biosynthesis J.Mol.Biol., 358, 2006
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2CFO
| Non-Discriminating Glutamyl-tRNA Synthetase from Thermosynechococcus elongatus in Complex with Glu | Descriptor: | GLUTAMIC ACID, GLUTAMYL-TRNA SYNTHETASE | Authors: | Schulze, J.O, Nickel, D, Schubert, W.-D, Jahn, D, Heinz, D.W. | Deposit date: | 2006-02-22 | Release date: | 2006-08-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal Structure of a Non-Discriminating Glutamyl- tRNA Synthetase. J.Mol.Biol., 361, 2006
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2BWN
| 5-Aminolevulinate Synthase from Rhodobacter capsulatus | Descriptor: | 5-AMINOLEVULINATE SYNTHASE, ACETIC ACID, CHLORIDE ION, ... | Authors: | Astner, I, Schulze, J.O, van den Heuvel, J.J, Jahn, D, Schubert, W.-D, Heinz, D.W. | Deposit date: | 2005-07-15 | Release date: | 2005-09-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of 5-Aminolevulinate Synthase, the First Enzyme of Heme Biosynthesis, and its Link to Xlsa in Humans. Embo J., 24, 2005
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2BWP
| 5-Aminolevulinate Synthase from Rhodobacter capsulatus in complex with glycine | Descriptor: | 5-AMINOLEVULINATE SYNTHASE, ACETIC ACID, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE] | Authors: | Astner, I, Schulze, J.O, Van Den Heuvel, J.J, Jahn, D, Schubert, W.-D, Heinz, D.W. | Deposit date: | 2005-07-15 | Release date: | 2005-09-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure of 5-Aminolevulinate Synthase, the First Enzyme of Heme Biosynthesis, and its Link to Xlsa in Humans. Embo J., 24, 2005
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7UWB
| Citrus V-ATPase State 2, Highest-Resolution Class | Descriptor: | V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit AP1 fragment, V-type proton ATPase subunit AP2 fragment, ... | Authors: | Keon, K.A, Abdelaziz, R.A, Schulze, W.X, Schumacher, K, Rubinstein, J.L. | Deposit date: | 2022-05-03 | Release date: | 2022-07-06 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure of V-ATPase from citrus fruit. Structure, 30, 2022
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7UW9
| Citrus V-ATPase State 1, H in contact with subunit a | Descriptor: | V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit AP1 fragment, V-type proton ATPase subunit AP2 fragment, ... | Authors: | Keon, K.A, Abdelaziz, R.A, Schulze, W.X, Schumacher, K, Rubinstein, J.L. | Deposit date: | 2022-05-03 | Release date: | 2022-07-06 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structure of V-ATPase from citrus fruit. Structure, 30, 2022
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7UWD
| Citrus V-ATPase State 2, H in contact with subunits AB | Descriptor: | V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit, V-type proton ATPase subunit AP1 fragment, ... | Authors: | Keon, K.A, Abdelaziz, R.A, Schulze, W.X, Schumacher, K, Rubinstein, J.L. | Deposit date: | 2022-05-03 | Release date: | 2022-07-06 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structure of V-ATPase from citrus fruit. Structure, 30, 2022
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7UWA
| Citrus V-ATPase State 1, H in contact with subunits AB | Descriptor: | V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit AP1 fragment, V-type proton ATPase subunit AP2 fragment, ... | Authors: | Abdelaziz, R.A, Keon, K.A, Schulze, W.X, Schumacher, K, Rubinstein, J.L. | Deposit date: | 2022-05-03 | Release date: | 2022-07-06 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structure of V-ATPase from citrus fruit. Structure, 30, 2022
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7UWC
| Citrus V-ATPase State 2, H in contact with subunit a | Descriptor: | V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit AP1 fragment, V-type proton ATPase subunit AP2 fragment, ... | Authors: | Keon, K.A, Abdelaziz, R.A, Schulze, W.X, Schumacher, K, Rubinstein, J.L. | Deposit date: | 2022-05-03 | Release date: | 2022-07-06 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure of V-ATPase from citrus fruit. Structure, 30, 2022
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4WLJ
| High resolution crystal structure of human kynurenine aminotransferase-I in complex with aminooxyacetate | Descriptor: | 4'-DEOXY-4'-ACETYLYAMINO-PYRIDOXAL-5'-PHOSPHATE, Kynurenine--oxoglutarate transaminase 1 | Authors: | Nadvi, N.A, Salam, N.K, Park, J, Akladios, F.N, Kapoor, V, Collyer, C.A, Gorrell, M.D, Church, W.B. | Deposit date: | 2014-10-07 | Release date: | 2014-12-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | High resolution crystal structures of human kynurenine aminotransferase-I bound to PLP cofactor, and in complex with aminooxyacetate. Protein Sci., 26, 2017
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4WP0
| Crystal structure of human kynurenine aminotransferase-I with a C-terminal V5-hexahistidine tag | Descriptor: | Kynurenine--oxoglutarate transaminase 1 | Authors: | Nadvi, N.A, Salam, N.K, Park, J, Akladios, F.N, Kapoor, V, Collyer, C.A, Gorrell, M.D, Church, W.B. | Deposit date: | 2014-10-17 | Release date: | 2014-11-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of human kynurenine aminotransferase-I in a novel space group To be published
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4WLH
| High resolution crystal structure of human kynurenine aminotransferase-I bound to PLP cofactor | Descriptor: | Kynurenine--oxoglutarate transaminase 1 | Authors: | Nadvi, N.A, Salam, N.K, Park, J, Akladios, F.N, Kapoor, V, Collyer, C.A, Gorrell, M.D, Church, W.B. | Deposit date: | 2014-10-07 | Release date: | 2014-12-03 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | High resolution crystal structures of human kynurenine aminotransferase-I bound to PLP cofactor, and in complex with aminooxyacetate. Protein Sci., 26, 2017
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2WOQ
| Porphobilinogen Synthase (HemB) in Complex with 5-acetamido-4- oxohexanoic acid (Alaremycin 2) | Descriptor: | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ALAREMYCIN 2, ... | Authors: | Heinemann, I.U, Schulz, C, Schubert, W.-D, Heinz, D.W, Wang, Y.-G, Kobayashi, Y, Awa, Y, Wachi, M, Jahn, D, Jahn, M. | Deposit date: | 2009-07-27 | Release date: | 2009-10-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure of the heme biosynthetic Pseudomonas aeruginosa porphobilinogen synthase in complex with the antibiotic alaremycin. Antimicrob. Agents Chemother., 54, 2010
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