2BWP

5-Aminolevulinate Synthase from Rhodobacter capsulatus in complex with glycine

Summary for 2BWP

Entry DOI	10.2210/pdb2bwp/pdb
Related	2BWN 2BWO
Descriptor	5-AMINOLEVULINATE SYNTHASE, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], ACETIC ACID, ... (4 entities in total)
Functional Keywords	tetrapyrrole biosynthesis, heme biosynthesis, pyridoxal phosphate dependent, transferase, acyltransferase
Biological source	RHODOBACTER CAPSULATUS
Total number of polymer chains	4
Total formula weight	176100.63
Authors	Astner, I.,Schulze, J.O.,Van Den Heuvel, J.J.,Jahn, D.,Schubert, W.-D.,Heinz, D.W. (deposition date: 2005-07-15, release date: 2005-09-27, Last modification date: 2011-07-13)
Primary citation	Astner, I.,Schulze, J.O.,Van Den Heuvel, J.J.,Jahn, D.,Schubert, W.-D.,Heinz, D.W. Crystal Structure of 5-Aminolevulinate Synthase, the First Enzyme of Heme Biosynthesis, and its Link to Xlsa in Humans. Embo J., 24:3166-, 2005 Cited by PubMed: 16121195 DOI: 10.1038/SJ.EMBOJ.7600792 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation