4WLJ
High resolution crystal structure of human kynurenine aminotransferase-I in complex with aminooxyacetate
Summary for 4WLJ
Entry DOI | 10.2210/pdb4wlj/pdb |
Related | 4WLH |
Descriptor | Kynurenine--oxoglutarate transaminase 1, 4'-DEOXY-4'-ACETYLYAMINO-PYRIDOXAL-5'-PHOSPHATE (3 entities in total) |
Functional Keywords | lysine modification, transaminase, aminotransferase, alpha beta protein ligand, aoaa, deoxy aminopyridoxal phosphate, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: Q16773 |
Total number of polymer chains | 2 |
Total formula weight | 96500.17 |
Authors | Nadvi, N.A.,Salam, N.K.,Park, J.,Akladios, F.N.,Kapoor, V.,Collyer, C.A.,Gorrell, M.D.,Church, W.B. (deposition date: 2014-10-07, release date: 2014-12-03, Last modification date: 2023-09-27) |
Primary citation | Nadvi, N.A.,Salam, N.K.,Park, J.,Akladios, F.N.,Kapoor, V.,Collyer, C.A.,Gorrell, M.D.,Church, W.B. High resolution crystal structures of human kynurenine aminotransferase-I bound to PLP cofactor, and in complex with aminooxyacetate. Protein Sci., 26:727-736, 2017 Cited by PubMed: 28097769DOI: 10.1002/pro.3119 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.54 Å) |
Structure validation
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