6WEM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wem by Molmil](/molmil-images/mine/6wem) | Crimson 0.9 | Descriptor: | mCrimson 0.9 | Authors: | Ataie, N, Tran Tang, C, Sens, A, Lin, M.Z, Chu, J, Ng, H.L. | Deposit date: | 2020-04-02 | Release date: | 2021-04-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Crimson 0.9 To Be Published
|
|
4OQW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4oqw by Molmil](/molmil-images/mine/4oqw) | Crystal structure of mCardinal far-red fluorescent protein | Descriptor: | Fluorescent protein FP480 | Authors: | Burg, J.S, Chu, J, Lam, A.J, Lin, M.Z, Garcia, K.C. | Deposit date: | 2014-02-10 | Release date: | 2014-03-12 | Last modified: | 2014-05-14 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Non-invasive intravital imaging of cellular differentiation with a bright red-excitable fluorescent protein. Nat.Methods, 11, 2014
|
|
7RHA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rha by Molmil](/molmil-images/mine/7rha) | A new fluorescent protein darkmRuby at pH 5.0 | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, SULFATE ION, ... | Authors: | Huang, M, Ng, H.L, Zhang, S, Deng, M, Chu, J. | Deposit date: | 2021-07-16 | Release date: | 2022-07-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of a new fluorescent protein darkmRuby at pH 5.0 To Be Published
|
|
7RHB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rhb by Molmil](/molmil-images/mine/7rhb) | |
7RHD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rhd by Molmil](/molmil-images/mine/7rhd) | darkmRuby M94T/F96Y mutant at pH 7.5 | Descriptor: | 1,2-ETHANEDIOL, darkmRuby M94T/F96Y mutant | Authors: | Huang, M, Ng, H.L, Zhang, S, Deng, M, Chu, J. | Deposit date: | 2021-07-16 | Release date: | 2022-07-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A Long-range Interaction Affects Brightness and pH Stability of a Dark Fluorescent Protein To Be Published
|
|
7RHC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rhc by Molmil](/molmil-images/mine/7rhc) | A new fluorescent protein darkmRuby at pH 9.0 | Descriptor: | 1,2-ETHANEDIOL, darkmRuby | Authors: | Huang, M, Ng, H.L, Zhang, S, Deng, M, Chu, J. | Deposit date: | 2021-07-16 | Release date: | 2022-07-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A Long-range Interaction Affects Brightness and pH Stability of a Dark Fluorescent Protein To Be Published
|
|
6M63
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m63 by Molmil](/molmil-images/mine/6m63) | Crystal structure of a cAMP sensor G-Flamp1. | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Chimera of Cyclic nucleotide-gated potassium channel mll3241 and Yellow fluorescent protein | Authors: | Zhou, Z, Chen, S, Wang, L, Chu, J. | Deposit date: | 2020-03-12 | Release date: | 2021-09-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | A high-performance genetically encoded fluorescent indicator for in vivo cAMP imaging. Nat Commun, 13, 2022
|
|
6C68
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6c68 by Molmil](/molmil-images/mine/6c68) | MHC-independent t cell receptor A11 | Descriptor: | T-cell receptor alpha chain, T-cell receptor beta chain | Authors: | Lu, J, Van Laethem, F, Saba, I, Chu, J, Bhattacharya, A, Love, N.C, Tikhonova, A, Radaev, S, Sun, X, Ko, A, Arnon, T, Shifrut, E, Friedman, N, Weng, N, Singer, A, Sun, P.D. | Deposit date: | 2018-01-18 | Release date: | 2019-01-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Structure of MHC-Independent TCRs and Their Recognition of Native Antigen CD155. J Immunol., 204, 2020
|
|
8A0C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8a0c by Molmil](/molmil-images/mine/8a0c) | Capsular polysaccharide synthesis multienzyme in complex with CMP | Descriptor: | Bcs3, CYTIDINE-5'-MONOPHOSPHATE, GLYCEROL, ... | Authors: | Cifuente, J.O, Schulze, J, Bethe, A, Di Domenico, V, Litschko, C, Budde, I, Eidenberger, L, Thiesler, H, Ramon-Roth, I, Berger, M, Claus, H, DAngelo, C, Marina, A, Gerardy-Schahn, R, Schubert, M, Guerin, M.E, Fiebig, T. | Deposit date: | 2022-05-27 | Release date: | 2023-04-26 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A multi-enzyme machine polymerizes the Haemophilus influenzae type b capsule. Nat.Chem.Biol., 19, 2023
|
|
8A0M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8a0m by Molmil](/molmil-images/mine/8a0m) | Capsular polysaccharide synthesis multienzyme in complex with capsular polymer fragment | Descriptor: | Bcs3, MAGNESIUM ION, beta-D-ribosyl-(1->1)-D-ribitol-5-phosphate | Authors: | Cifuente, J.O, Schulze, J, Bethe, A, Di Domenico, V, Litschko, C, Budde, I, Eidenberger, L, Thiesler, H, Ramon-Roth, I, Berger, M, Claus, H, DAngelo, C, Marina, A, Gerardy-Schahn, R, Schubert, M, Guerin, M.E, Fiebig, T. | Deposit date: | 2022-05-29 | Release date: | 2023-04-26 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | A multi-enzyme machine polymerizes the Haemophilus influenzae type b capsule. Nat.Chem.Biol., 19, 2023
|
|
3EXF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3exf by Molmil](/molmil-images/mine/3exf) | Crystal structure of the pyruvate dehydrogenase (E1p) component of human pyruvate dehydrogenase complex | Descriptor: | MAGNESIUM ION, POTASSIUM ION, Pyruvate dehydrogenase E1 component subunit alpha, ... | Authors: | Kato, M, Wynn, R.M, Chuang, J.L, Tso, S.-C, Machius, M, Li, J, Chuang, D.T. | Deposit date: | 2008-10-16 | Release date: | 2008-11-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.998 Å) | Cite: | Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation: role of disordered phosphorylation loops. Structure, 16, 2008
|
|
3EXG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3exg by Molmil](/molmil-images/mine/3exg) | Crystal structure of the pyruvate dehydrogenase (E1p) component of human pyruvate dehydrogenase complex | Descriptor: | POTASSIUM ION, Pyruvate dehydrogenase E1 component subunit alpha, somatic form, ... | Authors: | Kato, M, Wynn, R.M, Chuang, J.L, Tso, S.-C, Machius, M, Li, J, Chuang, D.T. | Deposit date: | 2008-10-16 | Release date: | 2008-11-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.011 Å) | Cite: | Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation: role of disordered phosphorylation loops. Structure, 16, 2008
|
|
2II4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ii4 by Molmil](/molmil-images/mine/2ii4) | Crystal structure of a cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), Coenzyme A-bound form | Descriptor: | CHLORIDE ION, COENZYME A, Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex | Authors: | Kato, M, Wynn, R.M, Chuang, J.L, Brautigam, C.A, Custorio, M, Chuang, D.T. | Deposit date: | 2006-09-27 | Release date: | 2006-12-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain alpha-ketoacid dehydrogenase complex. Embo J., 25, 2006
|
|
2II3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ii3 by Molmil](/molmil-images/mine/2ii3) | Crystal structure of a cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), Oxidized Coenzyme A-bound form | Descriptor: | ACETATE ION, CHLORIDE ION, Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, ... | Authors: | Kato, M, Wynn, R.M, Chuang, J.L, Brautigam, C.A, Custorio, M, Chuang, D.T. | Deposit date: | 2006-09-27 | Release date: | 2006-12-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain alpha-ketoacid dehydrogenase complex. Embo J., 25, 2006
|
|
8QZP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8qzp by Molmil](/molmil-images/mine/8qzp) | Structure of the non-mitochondrial citrate synthase from Ananas comosus | Descriptor: | Citrate synthase | Authors: | Lo, Y.K, Bohn, S, Sendker, F.L, Schuller, J.M, Hochberg, G. | Deposit date: | 2023-10-28 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (4.15 Å) | Cite: | Frequent transitions in self-assembly across the evolution of a central metabolic enzyme. Biorxiv, 2024
|
|
8A6T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8a6t by Molmil](/molmil-images/mine/8a6t) | Cryo-EM structure of the electron bifurcating Fe-Fe hydrogenase HydABC complex from Thermoanaerobacter kivui in the reduced state | Descriptor: | 2 IRON/2 SULFUR/5 CARBONYL/2 WATER INORGANIC CLUSTER, Electron bifurcating hydrogenase subunit HydA1, Electron bifurcating hydrogenase subunit HydB, ... | Authors: | Kumar, A, Saura, P, Gamiz-Hernandez, A.P, Kaila, V.R.I, Mueller, V, Schuller, J.M. | Deposit date: | 2022-06-19 | Release date: | 2023-02-15 | Last modified: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular Basis of the Electron Bifurcation Mechanism in the [FeFe]-Hydrogenase Complex HydABC. J.Am.Chem.Soc., 145, 2023
|
|
8A5E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8a5e by Molmil](/molmil-images/mine/8a5e) | Cryo-EM structure of the electron bifurcating Fe-Fe hydrogenase HydABC complex from Acetobacterium woodii in the reduced state | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2 IRON/2 SULFUR/5 CARBONYL/2 WATER INORGANIC CLUSTER, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Kumar, A, Saura, P, Gamiz-Hernandez, A.P, Kaila, V.R.I, Mueller, V, Schuller, J.M. | Deposit date: | 2022-06-14 | Release date: | 2023-02-22 | Last modified: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Molecular Basis of the Electron Bifurcation Mechanism in the [FeFe]-Hydrogenase Complex HydABC. J.Am.Chem.Soc., 145, 2023
|
|
1TJ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tj1 by Molmil](/molmil-images/mine/1tj1) | Crystal structure of E. coli PutA proline dehydrogenase domain (residues 86-669) complexed with L-lactate | Descriptor: | (2S)-2-HYDROXYPROPANOIC ACID, Bifunctional putA protein, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Tanner, J.J, Zhang, M, White, T.A, Schuermann, J.P, Baban, B.A, Becker, D.F. | Deposit date: | 2004-06-03 | Release date: | 2004-10-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of the Escherichia coli PutA proline dehydrogenase domain in complex with competitive inhibitors Biochemistry, 43, 2004
|
|
1TJ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tj0 by Molmil](/molmil-images/mine/1tj0) | Crystal structure of E. coli PutA proline dehydrogenase domain (residues 86-669) co-crystallized with L-lactate | Descriptor: | (2S)-2-HYDROXYPROPANOIC ACID, Bifunctional putA protein, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Tanner, J.J, Zhang, M, White, T.A, Schuermann, J.P, Baban, B.A, Becker, D.F. | Deposit date: | 2004-06-02 | Release date: | 2004-10-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structures of the Escherichia coli PutA proline dehydrogenase domain in complex with competitive inhibitors Biochemistry, 43, 2004
|
|
1TIW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tiw by Molmil](/molmil-images/mine/1tiw) | Crystal structure of E. coli PutA proline dehydrogenase domain (residues 86-669) complexed with L-Tetrahydro-2-furoic acid | Descriptor: | Bifunctional putA protein, FLAVIN-ADENINE DINUCLEOTIDE, TETRAHYDROFURAN-2-CARBOXYLIC ACID | Authors: | Tanner, J.J, Zhang, M, White, T.A, Schuermann, J.P, Baban, B.A, Becker, D.F. | Deposit date: | 2004-06-02 | Release date: | 2004-10-26 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of the Escherichia coli PutA proline dehydrogenase domain in complex with competitive inhibitors Biochemistry, 43, 2004
|
|
5DED
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ded by Molmil](/molmil-images/mine/5ded) | Crystal structure of the small alarmone synthethase 1 from Bacillus subtilis bound to its product pppGpp | Descriptor: | GTP pyrophosphokinase YjbM, MAGNESIUM ION, guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate) | Authors: | Steinchen, W, Schuhmacher, J.S, Altegoer, F, Bange, G. | Deposit date: | 2015-08-25 | Release date: | 2015-10-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.942 Å) | Cite: | Catalytic mechanism and allosteric regulation of an oligomeric (p)ppGpp synthetase by an alarmone. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
1SZ7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1sz7 by Molmil](/molmil-images/mine/1sz7) | Crystal structure of Human Bet3 | Descriptor: | PALMITIC ACID, Trafficking protein particle complex subunit 3 | Authors: | Turnbull, A.P, Prinz, B, Holz, C, Behlke, J, Schultchen, J, Delbrueck, H, Niesen, F.H, Lang, C, Heinemann, U. | Deposit date: | 2004-04-05 | Release date: | 2005-01-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structure of palmitoylated BET3: insights into TRAPP complex assembly and membrane localization Embo J., 24, 2005
|
|
5DEC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5dec by Molmil](/molmil-images/mine/5dec) | |
7TD0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7td0 by Molmil](/molmil-images/mine/7td0) | Lysophosphatidic acid receptor 1-Gi complex bound to LPA | Descriptor: | (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Liu, S, Paknejad, N, Zhu, L, Kihara, Y, Ray, D, Chun, J, Liu, W, Hite, R.K, Huang, X.Y. | Deposit date: | 2021-12-30 | Release date: | 2022-02-09 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (2.83 Å) | Cite: | Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate. Nat Commun, 13, 2022
|
|
7TD2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7td2 by Molmil](/molmil-images/mine/7td2) | Lysophosphatidic acid receptor 1-Gi complex bound to LPA, state a | Descriptor: | (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Liu, S, Paknejad, N, Zhu, L, Kihara, Y, Ray, D, Chun, J, Liu, W, Hite, R.K, Huang, X.Y. | Deposit date: | 2021-12-30 | Release date: | 2022-02-09 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate. Nat Commun, 13, 2022
|
|