8TOQ
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![BU of 8toq by Molmil](/molmil-images/mine/8toq) | ACE2-peptide 1 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, CHLORIDE ION, ... | 著者 | Christie, M, Payne, R.J. | 登録日 | 2023-08-03 | 公開日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity. Acs Chem.Biol., 19, 2024
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8TOS
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![BU of 8tos by Molmil](/molmil-images/mine/8tos) | ACE2-peptide 6 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, CHLORIDE ION, ... | 著者 | Christie, M, Payne, R. | 登録日 | 2023-08-03 | 公開日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity. Acs Chem.Biol., 19, 2024
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8TOR
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![BU of 8tor by Molmil](/molmil-images/mine/8tor) | ACE2-peptide 2 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Christie, M, Payne, R.J. | 登録日 | 2023-08-03 | 公開日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity. Acs Chem.Biol., 19, 2024
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8TOT
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![BU of 8tot by Molmil](/molmil-images/mine/8tot) | ACE2-peptide2 complex crystal form 2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Christie, M, Payne, R.J. | 登録日 | 2023-08-03 | 公開日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity. Acs Chem.Biol., 19, 2024
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5VAS
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![BU of 5vas by Molmil](/molmil-images/mine/5vas) | Pekin duck egg lysozyme isoform III (DEL-III), orthorhombic form | 分子名称: | GLYCEROL, Lysozyme, PHOSPHATE ION | 著者 | Christie, M, Christ, D, Langley, D.B. | 登録日 | 2017-03-27 | 公開日 | 2018-04-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural basis of antigen recognition: crystal structure of duck egg lysozyme. Acta Crystallogr D Struct Biol, 73, 2017
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7L4Z
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![BU of 7l4z by Molmil](/molmil-images/mine/7l4z) | Structure of SARS-CoV-2 spike RBD in complex with cyclic peptide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACE-DTY-LYS-ALA-GLY-VAL-VAL-TYR-GLY-TYR-ASN-ALA-TRP-ILE-ARG-CYS-NH2, Spike protein S1 | 著者 | Christie, M, Mackay, J.P, Passioura, T, Payne, R.J. | 登録日 | 2020-12-21 | 公開日 | 2021-06-30 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.96 Å) | 主引用文献 | Discovery of Cyclic Peptide Ligands to the SARS-CoV-2 Spike Protein Using mRNA Display. Acs Cent.Sci., 7, 2021
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6ARP
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![BU of 6arp by Molmil](/molmil-images/mine/6arp) | Structure of a mutant Cetuximab Fab fragment | 分子名称: | Cetuximab mutant Fab heavy chain,Immunoglobulin gamma-1 heavy chain, Cetuximab mutant light chain,Uncharacterized protein, GLYCEROL, ... | 著者 | Christie, M, Christ, D. | 登録日 | 2017-08-23 | 公開日 | 2018-08-29 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of a mutant Cetuximab Fab fragment To Be Published
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6ARU
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![BU of 6aru by Molmil](/molmil-images/mine/6aru) | Structure of Cetuximab Fab mutant in complex with EGFR extracellular domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab mutant heavy chain Fab fragment,Immunoglobulin gamma-1 heavy chain, ... | 著者 | Christie, M, Christ, D. | 登録日 | 2017-08-23 | 公開日 | 2018-08-29 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of Cetuximab Fab mutant in complex with EGFR extracellular domain To Be Published
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6BFT
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![BU of 6bft by Molmil](/molmil-images/mine/6bft) | |
6BGT
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![BU of 6bgt by Molmil](/molmil-images/mine/6bgt) | |
4CZW
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![BU of 4czw by Molmil](/molmil-images/mine/4czw) | |
4BWK
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![BU of 4bwk by Molmil](/molmil-images/mine/4bwk) | Structure of Neurospora crassa PAN3 pseudokinase | 分子名称: | PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN-3, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | 著者 | Christie, M, Boland, A, Huntzinger, E, Weichenrieder, O, Izaurralde, E. | 登録日 | 2013-07-04 | 公開日 | 2013-08-21 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structure of the Pan3 Pseudokinase Reveals the Basis for Interactions with the Pan2 Deadenylase and the Gw182 Proteins Mol.Cell, 51, 2013
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4BWP
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![BU of 4bwp by Molmil](/molmil-images/mine/4bwp) | Structure of Drosophila Melanogaster PAN3 pseudokinase | 分子名称: | AMP PHOSPHORAMIDATE, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN-3 | 著者 | Christie, M, Boland, A, Huntzinger, E, Weichenrieder, O, Izaurralde, E. | 登録日 | 2013-07-03 | 公開日 | 2013-08-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structure of the Pan3 Pseudokinase Reveals the Basis for Interactions with the Pan2 Deadenylase and the Gw182 Proteins Mol.Cell, 51, 2013
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4BWX
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![BU of 4bwx by Molmil](/molmil-images/mine/4bwx) | Structure of Neurospora crassa PAN3 pseudokinase mutant | 分子名称: | MAGNESIUM ION, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN-3, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | 著者 | Christie, M, Boland, A, Huntzinger, E, Weichenrieder, O, Izaurralde, E. | 登録日 | 2013-07-04 | 公開日 | 2013-08-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structure of the Pan3 Pseudokinase Reveals the Basis for Interactions with the Pan2 Deadenylase and the Gw182 Proteins Mol.Cell, 51, 2013
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5DLS
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![BU of 5dls by Molmil](/molmil-images/mine/5dls) | Identification of Novel, in vivo Active Chk1 Inhibitors Utilizing Structure Guided Drug Design | 分子名称: | 1-benzyl-N-(5-{5-[3-(dimethylamino)-2,2-dimethylpropoxy]-1H-indol-2-yl}-6-oxo-1,6-dihydropyridin-3-yl)-1H-pyrazole-4-carboxamide, SULFATE ION, Serine/threonine-protein kinase Chk1 | 著者 | Massey, A.J, Stokes, S, Browne, H, Foloppe, N, Fiumana, A, Scrace, S, Fallowfield, M, Bedford, S, Webb, P, Baker, L.M, Christie, M, Drysdale, M.J, Wood, M. | 登録日 | 2015-09-07 | 公開日 | 2015-10-14 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Identification of novel, in vivo active Chk1 inhibitors utilizing structure guided drug design. Oncotarget, 6, 2015
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6MH2
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![BU of 6mh2 by Molmil](/molmil-images/mine/6mh2) | Structure of Herceptin Fab without antigen | 分子名称: | Herceptin Fab arm heavy chain, Herceptin Fab arm light chain | 著者 | Luthra, A, Langley, D.B, Christie, M, Christ, D. | 登録日 | 2018-09-17 | 公開日 | 2019-05-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Human Antibody Bispecifics through Phage Display Selection. Biochemistry, 58, 2019
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8TOU
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![BU of 8tou by Molmil](/molmil-images/mine/8tou) | ACE2-peptide 2 complex crystal form 3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Franck, C, Payne, R.J, Christie, M. | 登録日 | 2023-08-04 | 公開日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity. Acs Chem.Biol., 19, 2024
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7RUQ
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![BU of 7ruq by Molmil](/molmil-images/mine/7ruq) | Structure of the human GIGYF1-TNRC6C complex | 分子名称: | GRB10-interacting GYF protein 1, Trinucleotide repeat-containing gene 6C protein | 著者 | Sobti, M, Mead, B.J, Igreja, C, Stewart, A.G, Christie, M. | 登録日 | 2021-08-18 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Molecular basis for GIGYF-TNRC6 complex assembly. Rna, 29, 2023
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7RUP
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![BU of 7rup by Molmil](/molmil-images/mine/7rup) | Structure of the human GIGYF2-TNRC6A complex | 分子名称: | GRB10-interacting GYF protein 2, SULFATE ION, Trinucleotide repeat-containing gene 6A protein | 著者 | Sobti, M, Mead, B.J, Igreja, C, Stewart, A.G, Christie, M. | 登録日 | 2021-08-18 | 公開日 | 2022-08-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | 主引用文献 | Molecular basis for GIGYF-TNRC6 complex assembly. Rna, 29, 2023
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4OIH
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![BU of 4oih by Molmil](/molmil-images/mine/4oih) | Importin Alpha in Complex with the Bipartite NLS of Prp20 | 分子名称: | Guanine nucleotide exchange factor SRM1, Importin subunit alpha-1 | 著者 | Roman, N, Christie, M, Swarbrick, C.M.D, Kobe, B, Forwood, J.K. | 登録日 | 2014-01-19 | 公開日 | 2014-02-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Characterisation of the Nuclear Import Receptor Importin Alpha in Complex with the Bipartite NLS of Prp20 Plos One, 8, 2013
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5UMZ
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![BU of 5umz by Molmil](/molmil-images/mine/5umz) | |