Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 21 件
8TOQ
DownloadVisualize
BU of 8toq by Molmil
ACE2-peptide 1 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, CHLORIDE ION, ...
著者Christie, M, Payne, R.J.
登録日2023-08-03
公開日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity.
Acs Chem.Biol., 19, 2024
8TOS
DownloadVisualize
BU of 8tos by Molmil
ACE2-peptide 6 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, CHLORIDE ION, ...
著者Christie, M, Payne, R.
登録日2023-08-03
公開日2024-02-07
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity.
Acs Chem.Biol., 19, 2024
8TOR
DownloadVisualize
BU of 8tor by Molmil
ACE2-peptide 2 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Christie, M, Payne, R.J.
登録日2023-08-03
公開日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity.
Acs Chem.Biol., 19, 2024
8TOT
DownloadVisualize
BU of 8tot by Molmil
ACE2-peptide2 complex crystal form 2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Christie, M, Payne, R.J.
登録日2023-08-03
公開日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity.
Acs Chem.Biol., 19, 2024
5VAS
DownloadVisualize
BU of 5vas by Molmil
Pekin duck egg lysozyme isoform III (DEL-III), orthorhombic form
分子名称: GLYCEROL, Lysozyme, PHOSPHATE ION
著者Christie, M, Christ, D, Langley, D.B.
登録日2017-03-27
公開日2018-04-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural basis of antigen recognition: crystal structure of duck egg lysozyme.
Acta Crystallogr D Struct Biol, 73, 2017
7L4Z
DownloadVisualize
BU of 7l4z by Molmil
Structure of SARS-CoV-2 spike RBD in complex with cyclic peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACE-DTY-LYS-ALA-GLY-VAL-VAL-TYR-GLY-TYR-ASN-ALA-TRP-ILE-ARG-CYS-NH2, Spike protein S1
著者Christie, M, Mackay, J.P, Passioura, T, Payne, R.J.
登録日2020-12-21
公開日2021-06-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.96 Å)
主引用文献Discovery of Cyclic Peptide Ligands to the SARS-CoV-2 Spike Protein Using mRNA Display.
Acs Cent.Sci., 7, 2021
6ARP
DownloadVisualize
BU of 6arp by Molmil
Structure of a mutant Cetuximab Fab fragment
分子名称: Cetuximab mutant Fab heavy chain,Immunoglobulin gamma-1 heavy chain, Cetuximab mutant light chain,Uncharacterized protein, GLYCEROL, ...
著者Christie, M, Christ, D.
登録日2017-08-23
公開日2018-08-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of a mutant Cetuximab Fab fragment
To Be Published
6ARU
DownloadVisualize
BU of 6aru by Molmil
Structure of Cetuximab Fab mutant in complex with EGFR extracellular domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab mutant heavy chain Fab fragment,Immunoglobulin gamma-1 heavy chain, ...
著者Christie, M, Christ, D.
登録日2017-08-23
公開日2018-08-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of Cetuximab Fab mutant in complex with EGFR extracellular domain
To Be Published
6BFT
DownloadVisualize
BU of 6bft by Molmil
Structure of Bevacizumab Fab mutant in complex with VEGF
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Avastin Heavy Chain Fab fragment mutant, Avastin Light Chain Fab fragment mutant, ...
著者Christie, M, Christ, D.
登録日2017-10-27
公開日2018-10-31
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Stable human IgG antibody therapeutics with native framework structure
To Be Published
6BGT
DownloadVisualize
BU of 6bgt by Molmil
Structure of Trastuzumab Fab mutant in complex with Her2 extracellular domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Herceptin heavy chain Fab fragment mutant, Herceptin light chain mutant, ...
著者Christie, M, Christ, D.
登録日2017-10-29
公開日2018-10-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Stable human IgG antibody therapeutics with native framework structure
To Be Published
4CZW
DownloadVisualize
BU of 4czw by Molmil
Structure of the Neurospora crassa Pan2 catalytic unit (protease and nuclease domain)
分子名称: PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN2, ZINC ION
著者Christie, M, Izaurralde, E, Weichenrieder, O.
登録日2014-04-22
公開日2014-06-04
最終更新日2014-07-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay.
Nat.Struct.Mol.Biol., 21, 2014
4BWK
DownloadVisualize
BU of 4bwk by Molmil
Structure of Neurospora crassa PAN3 pseudokinase
分子名称: PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN-3, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Christie, M, Boland, A, Huntzinger, E, Weichenrieder, O, Izaurralde, E.
登録日2013-07-04
公開日2013-08-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of the Pan3 Pseudokinase Reveals the Basis for Interactions with the Pan2 Deadenylase and the Gw182 Proteins
Mol.Cell, 51, 2013
4BWP
DownloadVisualize
BU of 4bwp by Molmil
Structure of Drosophila Melanogaster PAN3 pseudokinase
分子名称: AMP PHOSPHORAMIDATE, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN-3
著者Christie, M, Boland, A, Huntzinger, E, Weichenrieder, O, Izaurralde, E.
登録日2013-07-03
公開日2013-08-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structure of the Pan3 Pseudokinase Reveals the Basis for Interactions with the Pan2 Deadenylase and the Gw182 Proteins
Mol.Cell, 51, 2013
4BWX
DownloadVisualize
BU of 4bwx by Molmil
Structure of Neurospora crassa PAN3 pseudokinase mutant
分子名称: MAGNESIUM ION, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN-3, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Christie, M, Boland, A, Huntzinger, E, Weichenrieder, O, Izaurralde, E.
登録日2013-07-04
公開日2013-08-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure of the Pan3 Pseudokinase Reveals the Basis for Interactions with the Pan2 Deadenylase and the Gw182 Proteins
Mol.Cell, 51, 2013
5DLS
DownloadVisualize
BU of 5dls by Molmil
Identification of Novel, in vivo Active Chk1 Inhibitors Utilizing Structure Guided Drug Design
分子名称: 1-benzyl-N-(5-{5-[3-(dimethylamino)-2,2-dimethylpropoxy]-1H-indol-2-yl}-6-oxo-1,6-dihydropyridin-3-yl)-1H-pyrazole-4-carboxamide, SULFATE ION, Serine/threonine-protein kinase Chk1
著者Massey, A.J, Stokes, S, Browne, H, Foloppe, N, Fiumana, A, Scrace, S, Fallowfield, M, Bedford, S, Webb, P, Baker, L.M, Christie, M, Drysdale, M.J, Wood, M.
登録日2015-09-07
公開日2015-10-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Identification of novel, in vivo active Chk1 inhibitors utilizing structure guided drug design.
Oncotarget, 6, 2015
6MH2
DownloadVisualize
BU of 6mh2 by Molmil
Structure of Herceptin Fab without antigen
分子名称: Herceptin Fab arm heavy chain, Herceptin Fab arm light chain
著者Luthra, A, Langley, D.B, Christie, M, Christ, D.
登録日2018-09-17
公開日2019-05-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Human Antibody Bispecifics through Phage Display Selection.
Biochemistry, 58, 2019
8TOU
DownloadVisualize
BU of 8tou by Molmil
ACE2-peptide 2 complex crystal form 3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Franck, C, Payne, R.J, Christie, M.
登録日2023-08-04
公開日2024-02-07
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity.
Acs Chem.Biol., 19, 2024
7RUQ
DownloadVisualize
BU of 7ruq by Molmil
Structure of the human GIGYF1-TNRC6C complex
分子名称: GRB10-interacting GYF protein 1, Trinucleotide repeat-containing gene 6C protein
著者Sobti, M, Mead, B.J, Igreja, C, Stewart, A.G, Christie, M.
登録日2021-08-18
公開日2022-08-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Molecular basis for GIGYF-TNRC6 complex assembly.
Rna, 29, 2023
7RUP
DownloadVisualize
BU of 7rup by Molmil
Structure of the human GIGYF2-TNRC6A complex
分子名称: GRB10-interacting GYF protein 2, SULFATE ION, Trinucleotide repeat-containing gene 6A protein
著者Sobti, M, Mead, B.J, Igreja, C, Stewart, A.G, Christie, M.
登録日2021-08-18
公開日2022-08-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Molecular basis for GIGYF-TNRC6 complex assembly.
Rna, 29, 2023
4OIH
DownloadVisualize
BU of 4oih by Molmil
Importin Alpha in Complex with the Bipartite NLS of Prp20
分子名称: Guanine nucleotide exchange factor SRM1, Importin subunit alpha-1
著者Roman, N, Christie, M, Swarbrick, C.M.D, Kobe, B, Forwood, J.K.
登録日2014-01-19
公開日2014-02-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Characterisation of the Nuclear Import Receptor Importin Alpha in Complex with the Bipartite NLS of Prp20
Plos One, 8, 2013
5UMZ
DownloadVisualize
BU of 5umz by Molmil
Structure of TNRC6A NLS in complex with importin-alpha
分子名称: GLYCEROL, Importin subunit alpha-1, TNRC6A
著者Chaston, J, Stewart, A.G, Christie, M.
登録日2017-01-30
公開日2017-12-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural characterisation of TNRC6A nuclear localisation signal in complex with importin-alpha.
PLoS ONE, 12, 2017

224004

件を2024-08-21に公開中

PDB statisticsPDBj update infoContact PDBjnumon