7L4Z

Structure of SARS-CoV-2 spike RBD in complex with cyclic peptide

Summary for 7L4Z

• Entry DOI: 10.2210/pdb7l4z/pdb
• Descriptor: Spike protein S1, ACE-DTY-LYS-ALA-GLY-VAL-VAL-TYR-GLY-TYR-ASN-ALA-TRP-ILE-ARG-CYS-NH2, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: covid-19, spike, rbd, cyclic peptide, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 10
• Total formula weight: 140250.00

Authors

Christie, M.,Mackay, J.P.,Passioura, T.,Payne, R.J. (deposition date: 2020-12-21, release date: 2021-06-30, Last modification date: 2023-10-18)

• Primary citation: Norman, A.,Franck, C.,Christie, M.,Hawkins, P.M.E.,Patel, K.,Ashhurst, A.S.,Aggarwal, A.,Low, J.K.K.,Siddiquee, R.,Ashley, C.L.,Steain, M.,Triccas, J.A.,Turville, S.,Mackay, J.P.,Passioura, T.,Payne, R.J.; Discovery of Cyclic Peptide Ligands to the SARS-CoV-2 Spike Protein Using mRNA Display.; Acs Cent.Sci., 7:1001-1008, 2021; PubMed: 34230894; DOI: 10.1021/acscentsci.0c01708

Experimental method

X-RAY DIFFRACTION (3.96 Å)