6WYA
| RTX (Reverse Transcription Xenopolymerase) in complex with a DNA duplex and dAMPNPP | Descriptor: | 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | Authors: | Choi, W.S, He, P, Pothukuchy, A, Gollihar, J, Ellington, A.D, Yang, W. | Deposit date: | 2020-05-12 | Release date: | 2020-08-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | How a B family DNA polymerase has been evolved to copy RNA. Proc.Natl.Acad.Sci.USA, 117, 2020
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6WYB
| RTX (Reverse Transcription Xenopolymerase) in complex with an RNA/DNA hybrid | Descriptor: | 1,2-ETHANEDIOL, 3,3',3''-phosphanetriyltripropanoic acid, DNA polymerase, ... | Authors: | Choi, W.S, He, P, Pothukuchy, A, Gollihar, J, Ellington, A.D, Yang, W. | Deposit date: | 2020-05-12 | Release date: | 2020-08-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | How a B family DNA polymerase has been evolved to copy RNA. Proc.Natl.Acad.Sci.USA, 117, 2020
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7LBX
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7LBW
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8G17
| CryoEM structure of wild-type GAPDH | Descriptor: | Glyceraldehyde-3-phosphate dehydrogenase | Authors: | Choi, W.Y, Wu, H, Cheng, Y.F. | Deposit date: | 2023-02-01 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (1.98 Å) | Cite: | Efficient tagging of endogenous proteins in human cell lines for structural studies by single-particle cryo-EM. Proc.Natl.Acad.Sci.USA, 120, 2023
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8G13
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8G12
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8G15
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8G16
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8G14
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7KQN
| Ternary complex of TERT (telomerase reverse transcriptase) with RNA template, DNA primer, an incoming dGTP and a downstream hybrid duplex | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | Authors: | Choi, W.S, Weng, P.J, Yang, W. | Deposit date: | 2020-11-17 | Release date: | 2022-03-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Flexibility of telomerase in binding the RNA template and DNA telomeric repeat. Proc.Natl.Acad.Sci.USA, 119, 2022
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7KQM
| Binary complex of TERT (telomerase reverse transcriptase) with RNA/telomeric DNA hybrid | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*TP*TP*CP*TP*TP*TP*GP*TP*GP*CP*AP*CP*CP*TP*G)-3'), ... | Authors: | Choi, W.S, Weng, P.J, Yang, W. | Deposit date: | 2020-11-17 | Release date: | 2022-03-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Flexibility of telomerase in binding the RNA template and DNA telomeric repeat. Proc.Natl.Acad.Sci.USA, 119, 2022
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7KYQ
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7KYS
| Crystal structure of human BCCIP beta (Native2) | Descriptor: | 1,2-ETHANEDIOL, BRCA2 and CDKN1A-interacting protein, DI(HYDROXYETHYL)ETHER | Authors: | Choi, W.S, Liu, B, Shen, Z, Yang, W. | Deposit date: | 2020-12-08 | Release date: | 2021-06-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of human BCCIP and implications for binding and modification of partner proteins. Protein Sci., 30, 2021
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2XXN
| Structure of the vIRF4-HAUSP TRAF domain complex | Descriptor: | K10, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 | Authors: | Choi, W.C, Hwang, J, Kim, M.H. | Deposit date: | 2010-11-11 | Release date: | 2011-11-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Bilateral Inhibition of Hausp Deubiquitinase by a Viral Interferon Regulatory Factor Protein Nat.Struct.Mol.Biol., 18, 2011
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3NIL
| The structure of UBR box (RDAA) | Descriptor: | ACETATE ION, E3 ubiquitin-protein ligase UBR1, Peptide RDAA, ... | Authors: | Choi, W.S, Jeong, B.-C, Lee, M.-R, Song, H.K. | Deposit date: | 2010-06-16 | Release date: | 2010-09-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases Nat.Struct.Mol.Biol., 17, 2010
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3NIS
| The structure of UBR box (native2) | Descriptor: | ACETATE ION, E3 ubiquitin-protein ligase UBR1, ZINC ION | Authors: | Choi, W.S, Jeong, B.-C, Lee, M.-R, Song, H.K. | Deposit date: | 2010-06-16 | Release date: | 2010-09-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases Nat.Struct.Mol.Biol., 17, 2010
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4CAK
| Three-dimensional reconstruction of intact human integrin alphaIIbbeta3 in a phospholipid bilayer nanodisc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin alpha-IIb, ... | Authors: | Choi, W.S, Rice, W.J, Stokes, D.L, Coller, B.S. | Deposit date: | 2013-10-08 | Release date: | 2013-10-30 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (20.5 Å) | Cite: | Three-Dimensional Reconstruction of Intact Human Integrin Alphaiibbeta3; New Implications for Activation-Dependent Ligand Binding. Blood, 122, 2013
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3E57
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3NIH
| The structure of UBR box (RIAAA) | Descriptor: | E3 ubiquitin-protein ligase UBR1, Peptide RIAAA, ZINC ION | Authors: | Choi, W.S, Jeong, B.-C, Lee, M.-R, Song, H.K. | Deposit date: | 2010-06-16 | Release date: | 2010-09-15 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases Nat.Struct.Mol.Biol., 17, 2010
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3NIK
| The structure of UBR box (REAA) | Descriptor: | E3 ubiquitin-protein ligase UBR1, Peptide REAA, ZINC ION | Authors: | Choi, W.S, Jeong, B.-C, Lee, M.-R, Song, H.K. | Deposit date: | 2010-06-16 | Release date: | 2010-09-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases Nat.Struct.Mol.Biol., 17, 2010
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3NII
| The structure of UBR box (KIAA) | Descriptor: | E3 ubiquitin-protein ligase UBR1, Peptide KIAA, ZINC ION | Authors: | Choi, W.S, Jeong, B.-C, Lee, M.-R, Song, H.K. | Deposit date: | 2010-06-16 | Release date: | 2010-09-15 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases Nat.Struct.Mol.Biol., 17, 2010
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3NIJ
| The structure of UBR box (HIAA) | Descriptor: | E3 ubiquitin-protein ligase UBR1, Peptide HIAA, ZINC ION | Authors: | Choi, W.S, Jeong, B.-C, Lee, M.-R, Song, H.K. | Deposit date: | 2010-06-16 | Release date: | 2010-09-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases Nat.Struct.Mol.Biol., 17, 2010
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3NIM
| The structure of UBR box (RRAA) | Descriptor: | E3 ubiquitin-protein ligase UBR1, Peptide RRAA, ZINC ION | Authors: | Choi, W.S, Jeong, B.-C, Lee, M.-R, Song, H.K. | Deposit date: | 2010-06-16 | Release date: | 2010-09-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases Nat.Struct.Mol.Biol., 17, 2010
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3NIN
| The structure of UBR box (RLGES) | Descriptor: | E3 ubiquitin-protein ligase UBR1, Peptide RLGES, ZINC ION | Authors: | Choi, W.S, Jeong, B.-C, Lee, M.-R, Song, H.K. | Deposit date: | 2010-06-16 | Release date: | 2010-09-15 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases Nat.Struct.Mol.Biol., 17, 2010
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