1UMI
 
 | | Structural basis of sugar-recognizing ubiquitin ligase | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, F-box only protein 2 | | Authors: | Mizushima, T, Hirao, T, Yoshida, Y, Lee, S.J, Chiba, T, Iwai, K, Yamaguchi, Y, Kato, K, Tsukihara, T, Tanaka, K. | | Deposit date: | 2003-10-01 | | Release date: | 2004-04-06 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis of sugar-recognizing ubiquitin ligase.
Nat.Struct.Mol.Biol., 11, 2004
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1UMH
 | | Structural basis of sugar-recognizing ubiquitin ligase | | Descriptor: | F-box only protein 2, NICKEL (II) ION | | Authors: | Mizushima, T, Hirao, T, Yoshida, Y, Lee, S.J, Chiba, T, Iwai, K, Yamaguchi, Y, Kato, K, Tsukihara, T, Tanaka, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-10-01 | | Release date: | 2004-04-06 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis of sugar-recognizing ubiquitin ligase
NAT.STRUCT.MOL.BIOL., 11, 2004
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6LUB
 | | Crystal Structure of EGFR(L858R/T790M/C797S) in complex with CH7233163 | | Descriptor: | Epidermal growth factor receptor, N-[2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-yl]-7-(4-methylpiperazin-1-yl)-5-propan-2-yl-9-[2,2,2-tris(fluoranyl)ethoxy]pyrido[4,3-b]indol-3-amine | | Authors: | Kawauchi, H, Fukami, T.A, Sato, S, Endo, M, Torizawa, T, Kashima, K, Chiba, T, Sakamoto, H. | | Deposit date: | 2020-01-27 | | Release date: | 2020-10-07 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.315 Å) | | Cite: | CH7233163 Overcomes Osimertinib-Resistant EGFR-Del19/T790M/C797S Mutation.
Mol.Cancer Ther., 19, 2020
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6LUD
 | | Crystal Structure of EGFR(L858R/T790M/C797S) in complex with Osimertinib | | Descriptor: | Epidermal growth factor receptor, N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide | | Authors: | Kawauchi, H, Fukami, T.A, Sato, S, Endo, M, Torizawa, T, Kashima, K, Chiba, T, Sakamoto, H. | | Deposit date: | 2020-01-27 | | Release date: | 2020-10-07 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | CH7233163 Overcomes Osimertinib-Resistant EGFR-Del19/T790M/C797S Mutation.
Mol.Cancer Ther., 19, 2020
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6KX0
 | | Crystal structure of SN-101 mAb non-liganded form | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Fab Fragment-SN-101-Heavy chain, Fab Fragment-SN-101-Light chain | | Authors: | Wakui, H, Tanaka, Y, Kato, K, Ose, T, Matsumoto, I, Min, Y, Tachibana, T, Nishimura, S.-I. | | Deposit date: | 2019-09-09 | | Release date: | 2020-07-29 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.404 Å) | | Cite: | A straightforward approach to antibodies recognising cancer specific glycopeptidic neoepitopes
Chem Sci, 11, 2020
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6KX1
 | | Crystal structure of SN-101 mAb in complex with MUC1 glycopeptide | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, Fab Fragment-SN-101-Heavy chain, Fab Fragment-SN-101-Light chain, ... | | Authors: | Wakui, H, Tanaka, Y, Kato, K, Ose, T, Matsumoto, I, Min, Y, Tachibana, T, Nishimura, S.-I. | | Deposit date: | 2019-09-09 | | Release date: | 2020-07-29 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.773 Å) | | Cite: | A straightforward approach to antibodies recognising cancer specific glycopeptidic neoepitopes
Chem Sci, 11, 2020
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