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PDB: 16 件
4AD6
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BU of 4ad6 by Molmil
Synthesis and SAR of guanine based analogues for HPPK inhibitors
分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 7-(2-HYDROXYETHYL)-8-MERCAPTOGUANINE
著者Chhabra, S, Peat, T.S, Swarbrick, J.
登録日2011-12-22
公開日2013-01-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Exploring the Chemical Space Around 8-Mercaptoguanine as a Route to New Inhibitors of the Folate Biosynthesis Enzyme Hppk.
Plos One, 8, 2013
5U0W
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BU of 5u0w by Molmil
E. coli dihydropteroate synthase complexed with 9-methylguanine
分子名称: 9-METHYLGUANINE, ACETIC ACID, Dihydropteroate synthase
著者Chhabra, S, Dennis, M.L, Peat, T.S, Swarbrick, J.D.
登録日2016-11-27
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.968 Å)
主引用文献8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase.
Chemistry, 24, 2018
2MCR
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BU of 2mcr by Molmil
Solution structure of ShK-like immunomodulatory peptide from Brugia malayi (filarial worm)
分子名称: Probable zinc metalloproteinase, putative
著者Chhabra, S, Swarbrick, J.D, Pennington, M.W, Chang, S.C, Norton, R.S.
登録日2013-08-22
公開日2014-07-02
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases.
Faseb J., 28, 2014
2MD0
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BU of 2md0 by Molmil
Solution structure of ShK-like immunomodulatory peptide from Ancylostoma caninum (hookworm)
分子名称: AcK1
著者Chhabra, S, Swarbrick, J.D, Mohanty, B, Chang, S.C, Chandy, G.K, Pennington, M.W, Norton, R.S.
登録日2013-08-28
公開日2014-07-02
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases.
Faseb J., 28, 2014
2MTU
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BU of 2mtu by Molmil
Non-reducible analogues of alpha-conotoxin RgIA: [3,12]-trans dicarba RgIA
分子名称: Dicarba Analogues of alpha-Conotoxin RgIA
著者Chhabra, S, Robinson, S.D, Norton, R.S.
登録日2014-09-01
公開日2014-11-26
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Dicarba Analogues of alpha-Conotoxin RgIA. Structure, Stability, and Activity at Potential Pain Targets.
J.Med.Chem., 57, 2014
2MTO
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BU of 2mto by Molmil
Non-reducible analogues of alpha-conotoxin RgIA: [2,8]-cis dicarba RgIA
分子名称: Alpha-conotoxin RgIA
著者Chhabra, S, Robinson, S, Norton, R.
登録日2014-08-26
公開日2014-11-26
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Dicarba Analogues of alpha-Conotoxin RgIA. Structure, Stability, and Activity at Potential Pain Targets.
J.Med.Chem., 57, 2014
2MTT
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BU of 2mtt by Molmil
Non-reducible analogues of alpha-conotoxin RgIA: [3,12]-cis dicarba RgIA
分子名称: Dicarba Analogues of alpha-Conotoxin RgIA
著者Chhabra, S, Robinson, S.D, Norton, R.S.
登録日2014-08-31
公開日2014-11-26
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Dicarba Analogues of alpha-Conotoxin RgIA. Structure, Stability, and Activity at Potential Pain Targets.
J.Med.Chem., 57, 2014
3MMW
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BU of 3mmw by Molmil
Crystal structure of endoglucanase Cel5A from the hyperthermophilic Thermotoga maritima
分子名称: CADMIUM ION, Endoglucanase
著者Pereira, J.H, Chen, Z, McAndrew, R.P, Sapra, R, Chhabra, S.R, Sale, K.L.
登録日2010-04-20
公開日2010-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Biochemical characterization and crystal structure of endoglucanase Cel5A from the hyperthermophilic Thermotoga maritima.
J.Struct.Biol., 172, 2010
3MMU
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Crystal structure of endoglucanase Cel5A from the hyperthermophilic Thermotoga maritima
分子名称: CADMIUM ION, Endoglucanase, NICKEL (II) ION
著者Pereira, J.H, Chen, Z, McAndrew, R.P, Sapra, R, Chhabra, S.R, Sale, K.L, Simmons, B.A, Adams, P.D.
登録日2010-04-20
公開日2010-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Biochemical characterization and crystal structure of endoglucanase Cel5A from the hyperthermophilic Thermotoga maritima.
J.Struct.Biol., 172, 2010
7KNN
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BU of 7knn by Molmil
Solution structure of the alpha-conotoxin analogue [2-8]-alkyne Vc1.1
分子名称: Alpha-conotoxin Vc1a
著者MacRaild, C.A, Robinson, S.D, Chhabra, S, Norton, R.S.
登録日2020-11-05
公開日2021-09-15
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Alkyne-Bridged alpha-Conotoxin Vc1.1 Potently Reverses Mechanical Allodynia in Neuropathic Pain Models.
J.Med.Chem., 64, 2021
5L34
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BU of 5l34 by Molmil
Calculated solution structure of [D-Trp3]-Contryphan-Vc2
分子名称: [D-Trp3]-Contryphan-Vc2
著者Drane, S.B, Chhabra, S, MacRaild, C.A.
登録日2016-08-03
公開日2017-03-08
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Structure and activity of contryphan-Vc2: Importance of the d-amino acid residue.
Toxicon, 129, 2017
3QBC
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BU of 3qbc by Molmil
Structure and design of a new pterin site inhibitor of S. aureus HPPK
分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 2-amino-8-sulfanyl-1,9-dihydro-6H-purin-6-one
著者Peat, T.S, Chhabra, S, Swarbrick, J.D.
登録日2011-01-12
公開日2012-01-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of S. aureus HPPK and the discovery of a new substrate site inhibitor
Plos One, 7, 2012
3PSN
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BU of 3psn by Molmil
Crystal structure of mouse VPS29 complexed with Mn2+
分子名称: MANGANESE (II) ION, Vacuolar protein sorting-associated protein 29
著者Swarbrick, J, Shaw, D, Chhabra, S, Ghai, R, Valkov, E, Norwood, S, Collins, B.
登録日2010-12-02
公開日2010-12-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Conformational dynamics and biomolecular interactions of VPS29 studied by NMR and X-ray crystallography
To be Published
3PSO
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BU of 3pso by Molmil
Crystal structure of mouse VPS29 complexed with Zn2+
分子名称: Vacuolar protein sorting-associated protein 29, ZINC ION
著者Swarbrick, J, Shaw, D, Chhabra, S, Ghai, R, Valkov, E, Norwood, S, Collins, B.
登録日2010-12-02
公開日2010-12-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Conformational dynamics and biomolecular interactions of VPS29 studied by NMR and X-ray crystallography
To be Published
2N24
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BU of 2n24 by Molmil
Solution NMR structure of Contryphan-Vc1
分子名称: O2_contryphan_Vc1
著者Robinson, S.D, Chhabra, S, Norton, R.S.
登録日2015-04-27
公開日2016-02-03
最終更新日2019-12-25
実験手法SOLUTION NMR
主引用文献A Naturally Occurring Peptide with an Elementary Single Disulfide-Directed beta-Hairpin Fold.
Structure, 24, 2016
2N8H
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BU of 2n8h by Molmil
Structural basis for the inhibition of voltage-gated sodium channels with conotoxin-muOxi-GVIIJ
分子名称: conotoxin-muOxi-GVIIJ
著者Green, B.R, Chhabra, S, Norton, R.S.
登録日2015-10-15
公開日2016-02-03
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural Basis for the Inhibition of Voltage-gated Sodium Channels by Conotoxin mu O-GVIIJ.
J.Biol.Chem., 291, 2016

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件を2024-07-03に公開中

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