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PDB: 87 results

4WB8
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Crystal structure of human cAMP-dependent protein kinase A (catalytic alpha subunit), exon 1 deletion
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Cheung, J, Ginter, C, Cassidy, M, Franklin, M.C, Rudolph, M.J, Hendrickson, W.A.
Deposit date:2014-09-02
Release date:2015-01-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural insights into mis-regulation of protein kinase A in human tumors.
Proc.Natl.Acad.Sci.USA, 112, 2015
4WB7
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Crystal structure of a chimeric fusion of human DnaJ (Hsp40) and cAMP-dependent protein kinase A (catalytic alpha subunit)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha, PKI (5-24), ...
Authors:Cheung, J, Ginter, C, Cassidy, M, Franklin, M.C, Rudolph, M.J, Hendrickson, W.A.
Deposit date:2014-09-02
Release date:2015-01-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into mis-regulation of protein kinase A in human tumors.
Proc.Natl.Acad.Sci.USA, 112, 2015
4WB6
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Crystal structure of a L205R mutant of human cAMP-dependent protein kinase A (catalytic alpha subunit)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PKI (5-24), ...
Authors:Cheung, J, Ginter, C, Cassidy, M, Franklin, M.C, Rudolph, M.J, Hendrickson, W.A.
Deposit date:2014-09-02
Release date:2015-01-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insights into mis-regulation of protein kinase A in human tumors.
Proc.Natl.Acad.Sci.USA, 112, 2015
4WB5
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BU of 4wb5 by Molmil
Crystal structure of human cAMP-dependent protein kinase A (catalytic alpha subunit)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PKI (5-24), ...
Authors:Cheung, J, Ginter, C, Cassidy, M, Franklin, M.C, Rudolph, M.J, Hendrickson, W.A.
Deposit date:2014-09-02
Release date:2015-01-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.641 Å)
Cite:Structural insights into mis-regulation of protein kinase A in human tumors.
Proc.Natl.Acad.Sci.USA, 112, 2015
4EY8
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Crystal structure of recombinant human acetylcholinesterase in complex with fasciculin-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, Fasciculin-2, ...
Authors:Cheung, J, Rudolph, M, Burshteyn, F, Cassidy, M, Gary, E, Love, J, Height, J, Franklin, M.
Deposit date:2012-05-01
Release date:2012-10-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5958 Å)
Cite:Structures of human acetylcholinesterase in complex with pharmacologically important ligands.
J.Med.Chem., 55, 2012
4EY6
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Crystal Structure of Recombinant Human Acetylcholinesterase in Complex with (-)-galantamine
Descriptor: (-)-GALANTHAMINE, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Cheung, J, Rudolph, M, Burshteyn, F, Cassidy, M, Gary, E, Love, J, Height, J, Franklin, M.
Deposit date:2012-05-01
Release date:2012-10-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3983 Å)
Cite:Structures of human acetylcholinesterase in complex with pharmacologically important ligands.
J.Med.Chem., 55, 2012
4EY5
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Crystal Structure of Recombinant Human Acetylcholinesterase in Complex with (-)-huperzine A
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Cheung, J, Rudolph, M, Burshteyn, F, Cassidy, M, Gary, E, Love, J, Height, J, Franklin, M.
Deposit date:2012-05-01
Release date:2012-10-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3012 Å)
Cite:Structures of human acetylcholinesterase in complex with pharmacologically important ligands.
J.Med.Chem., 55, 2012
4EY4
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Crystal Structure of Recombinant Human Acetylcholinesterase in the Apo state
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Cheung, J, Rudolph, M, Burshteyn, F, Cassidy, M, Gary, E, Love, J, Height, J, Franklin, M.
Deposit date:2012-05-01
Release date:2012-10-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.156 Å)
Cite:Structures of human acetylcholinesterase in complex with pharmacologically important ligands.
J.Med.Chem., 55, 2012
4EY7
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Crystal Structure of Recombinant Human Acetylcholinesterase in Complex with Donepezil
Descriptor: 1,2-ETHANEDIOL, 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Cheung, J, Rudolph, M, Burshteyn, F, Cassidy, M, Gary, E, Love, J, Height, J, Franklin, M.
Deposit date:2012-05-01
Release date:2012-10-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3509 Å)
Cite:Structures of human acetylcholinesterase in complex with pharmacologically important ligands.
J.Med.Chem., 55, 2012
3EZI
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BU of 3ezi by Molmil
Crystal Structure of the E. coli Histidine Kinase NarX Sensor Domain without Ligand
Descriptor: ISOPROPYL ALCOHOL, Nitrate/nitrite sensor protein narX
Authors:Cheung, J, Hendrickson, W.A.
Deposit date:2008-10-22
Release date:2008-12-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Analysis of Ligand Stimulation of the Histidine Kinase NarX.
Structure, 17, 2009
3EZH
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Crystal Structure of the E. coli Histidine Kinase NarX Sensor Domain in Complex with Nitrate
Descriptor: NITRATE ION, Nitrate/nitrite sensor protein narX
Authors:Cheung, J, Hendrickson, W.A.
Deposit date:2008-10-22
Release date:2008-12-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Analysis of Ligand Stimulation of the Histidine Kinase NarX.
Structure, 17, 2009
3H7M
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BU of 3h7m by Molmil
Crystal Structure of a Histidine Kinase Sensor Domain with Similarity to Periplasmic Binding Proteins
Descriptor: SODIUM ION, Sensor protein
Authors:Cheung, J, Le-Khac, M, Hendrickson, W.A.
Deposit date:2009-04-27
Release date:2009-06-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of a histidine kinase sensor domain with similarity to periplasmic binding proteins.
Proteins, 77, 2009
5W5A
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BU of 5w5a by Molmil
Crystal structure of Mycobacterium tuberculosis CRP-FNR family transcription factor Cmr (Rv1675c)
Descriptor: CHLORIDE ION, HTH-type transcriptional regulator Cmr, SULFATE ION
Authors:Cheung, J, Cassidy, M, Ginter, C, Ranganathan, S, Pata, D.J, McDonough, K.A.
Deposit date:2017-06-14
Release date:2017-12-13
Last modified:2019-01-09
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Novel structural features drive DNA binding properties of Cmr, a CRP family protein in TB complex mycobacteria.
Nucleic Acids Res., 46, 2018
5W5B
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BU of 5w5b by Molmil
Crystal structure of Mycobacterium tuberculosis CRP-FNR family transcription factor Cmr (Rv1675c), truncated construct
Descriptor: CHLORIDE ION, HTH-type transcriptional regulator Cmr
Authors:Cheung, J, Cassidy, M, Ginter, C, Ranganathan, S, Pata, D.J, McDonough, K.A.
Deposit date:2017-06-14
Release date:2017-12-13
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Novel structural features drive DNA binding properties of Cmr, a CRP family protein in TB complex mycobacteria.
Nucleic Acids Res., 46, 2018
4M0F
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BU of 4m0f by Molmil
Structure of human acetylcholinesterase in complex with territrem B
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Cheung, J, Gary, E.N, Shiomi, K, Rosenberry, T.L.
Deposit date:2013-08-01
Release date:2013-10-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.304 Å)
Cite:Structures of human acetylcholinesterase bound to dihydrotanshinone I and territrem B show peripheral site flexibility.
ACS Med Chem Lett, 4, 2013
4M0E
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BU of 4m0e by Molmil
Structure of human acetylcholinesterase in complex with dihydrotanshinone I
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Cheung, J, Gary, E.N, Shiomi, K, Rosenberry, T.L.
Deposit date:2013-08-01
Release date:2013-10-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of human acetylcholinesterase bound to dihydrotanshinone I and territrem B show peripheral site flexibility.
ACS Med Chem Lett, 4, 2013
6ARY
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BU of 6ary by Molmil
Crystal structure of an insecticide-resistant acetylcholinesterase mutant from the malaria vector Anopheles gambiae in complex with a difluoromethyl ketone inhibitor
Descriptor: (1S)-2,2-difluoro-1-[1-(pentan-3-yl)-1H-pyrazol-4-yl]ethan-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ...
Authors:Cheung, J, Mahmood, A, Kalathur, R, Lixuan, L, Carlier, P.R.
Deposit date:2017-08-23
Release date:2018-01-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.257 Å)
Cite:Structure of the G119S Mutant Acetylcholinesterase of the Malaria Vector Anopheles gambiae Reveals Basis of Insecticide Resistance.
Structure, 26, 2018
6ARX
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BU of 6arx by Molmil
Crystal structure of an insecticide-resistant acetylcholinesterase mutant from the malaria vector Anopheles gambiae in the ligand-free state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, CHLORIDE ION, ...
Authors:Cheung, J, Mahmood, A, Kalathur, R, Lixuan, L, Carlier, P.R.
Deposit date:2017-08-23
Release date:2018-01-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:Structure of the G119S Mutant Acetylcholinesterase of the Malaria Vector Anopheles gambiae Reveals Basis of Insecticide Resistance.
Structure, 26, 2018
3TRK
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BU of 3trk by Molmil
Structure of the Chikungunya virus nsP2 protease
Descriptor: Nonstructural polyprotein, SODIUM ION
Authors:Cheung, J, Franklin, M, Mancia, F, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J.
Deposit date:2011-09-09
Release date:2011-09-28
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.397 Å)
Cite:Structure of the Chikungunya virus nsP2 protease
To be Published
7JO8
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BU of 7jo8 by Molmil
Crystal structure of a Chimeric Antigen Receptor (CAR) scFv domain rearrangement forming a VL-VL dimer
Descriptor: 47G4-CD828Z, MALONATE ION, PENTAETHYLENE GLYCOL, ...
Authors:Cheung, J, Hendrickson, W.A, Kochenderfer, J.N, Youkharibache, P.
Deposit date:2020-08-06
Release date:2021-02-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.399 Å)
Cite:Crystal Structure of a Chimeric Antigen Receptor (CAR) scFv Domain Rearrangement Forming a VL-VL Dimer
Crystals, 13, 2023
3TRJ
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BU of 3trj by Molmil
Structure of a phosphoheptose isomerase from Francisella tularensis
Descriptor: Phosphoheptose isomerase
Authors:Cheung, J, Franklin, M.C, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J.
Deposit date:2011-09-09
Release date:2011-09-21
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Rapid countermeasure discovery against Francisella tularensis based on a metabolic network reconstruction.
Plos One, 8, 2013
3TQW
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Structure of a ABC transporter, periplasmic substrate-binding protein from Coxiella burnetii
Descriptor: METHIONINE, Methionine-binding protein, SULFATE ION
Authors:Cheung, J, Franklin, M.C, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J.
Deposit date:2011-09-09
Release date:2011-09-21
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural genomics for drug design against the pathogen Coxiella burnetii.
Proteins, 83, 2015
3TRC
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BU of 3trc by Molmil
Structure of the GAF domain from a phosphoenolpyruvate-protein phosphotransferase (ptsP) from Coxiella burnetii
Descriptor: PHOSPHATE ION, Phosphoenolpyruvate-protein phosphotransferase, SODIUM ION
Authors:Cheung, J, Franklin, M.C, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J.
Deposit date:2011-09-09
Release date:2011-09-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural genomics for drug design against the pathogen Coxiella burnetii.
Proteins, 83, 2015
3TR2
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Structure of a orotidine 5'-phosphate decarboxylase (pyrF) from Coxiella burnetii
Descriptor: Orotidine 5'-phosphate decarboxylase
Authors:Cheung, J, Franklin, M, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J.
Deposit date:2011-09-09
Release date:2011-09-21
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structural genomics for drug design against the pathogen Coxiella burnetii.
Proteins, 83, 2015
3TRH
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Structure of a phosphoribosylaminoimidazole carboxylase catalytic subunit (purE) from Coxiella burnetii
Descriptor: Phosphoribosylaminoimidazole carboxylase carboxyltransferase subunit
Authors:Cheung, J, Franklin, M.C, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J.
Deposit date:2011-09-09
Release date:2011-09-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.203 Å)
Cite:Structural genomics for drug design against the pathogen Coxiella burnetii.
Proteins, 83, 2015

 

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數據於2024-05-15公開中

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