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PDB: 124 件

2IFW
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Crystal structure of scytalido-glutamic peptidase with a transition state analog inhibitor
分子名称: ACETIC ACID, GLYCEROL, Heptapeptide, ...
著者Pillai, B, Cherney, M.M, Hiraga, K, Takada, K, Oda, K, James, M.N.
登録日2006-09-21
公開日2006-10-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of scytalidoglutamic peptidase with its first potent inhibitor provides insights into substrate specificity and catalysis.
J.Mol.Biol., 365, 2007
3FHZ
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Crystal structure of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator and co-repressor, L-arginine
分子名称: 5'-D(*TP*GP*TP*TP*GP*CP*AP*TP*AP*AP*CP*GP*AP*TP*GP*CP*AP*AP*AP*A)-3', 5'-D(*TP*TP*TP*TP*GP*CP*AP*TP*CP*GP*TP*TP*AP*TP*GP*CP*AP*AP*CP*A)-3', ACETATE ION, ...
著者Cherney, L.T, Cherney, M.M, Garen, C.R, James, M.N.G, TB Structural Genomics Consortium (TBSGC)
登録日2008-12-10
公開日2009-03-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.27 Å)
主引用文献The structure of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator and Co-repressor, L-arginine.
J.Mol.Biol., 388, 2009
3EKM
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Crystal structure of diaminopimelate epimerase form arabidopsis thaliana in complex with irreversible inhibitor DL-AziDAP
分子名称: (2R,6S)-2,6-DIAMINO-2-METHYLHEPTANEDIOIC ACID, Diaminopimelate epimerase, chloroplastic
著者Pillai, B, Moorthie, V.A, Cherney, M.M, van Belkum, M.J, Vederas, J.C, James, M.N.G.
登録日2008-09-19
公開日2009-02-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of diaminopimelate epimerase from Arabidopsis thaliana, an amino acid racemase critical for L-lysine biosynthesis.
J.Mol.Biol., 385, 2009
3EI5
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Crystal structure of LL-diaminopimelate aminotransferase from Arabidopsis thaliana complexed with PLP-Glu: an external aldimine mimic
分子名称: GLYCEROL, LL-diaminopimelate aminotransferase, N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-glutamic acid, ...
著者Watanabe, N, Clay, M.D, van Belkum, M.J, Cherney, M.M, Vederas, J.C, James, M.N.G.
登録日2008-09-15
公開日2008-10-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Mechanism of substrate recognition and PLP-induced conformational changes in LL-diaminopimelate aminotransferase from Arabidopsis thaliana.
J.Mol.Biol., 384, 2008
3EIA
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Crystal structure of K270Q variant of LL-diaminopimelate aminotransferase from Arabidopsis thaliana complexed with L-Glu: External aldimine form
分子名称: (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-glutamic acid, LL-diaminopimelate aminotransferase, SULFATE ION
著者Watanabe, N, Clay, M.D, van Belkum, M.J, Cherney, M.M, Vederas, J.C, James, M.N.G.
登録日2008-09-15
公開日2008-10-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Mechanism of substrate recognition and PLP-induced conformational changes in LL-diaminopimelate aminotransferase from Arabidopsis thaliana.
J.Mol.Biol., 384, 2008
3EI7
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Crystal structure of apo-LL-diaminopimelate aminotransferase from Arabidopsis thaliana (no PLP)
分子名称: LL-diaminopimelate aminotransferase, SULFATE ION
著者Watanabe, N, Clay, M.D, van Belkum, M.J, Cherney, M.M, Vederas, J.C, James, M.N.G.
登録日2008-09-15
公開日2008-10-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Mechanism of substrate recognition and PLP-induced conformational changes in LL-diaminopimelate aminotransferase from Arabidopsis thaliana.
J.Mol.Biol., 384, 2008
2P2G
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Crystal Structure of Ornithine Carbamoyltransferase from Mycobacterium Tuberculosis (Rv1656): Orthorhombic Form
分子名称: Ornithine carbamoyltransferase, SULFATE ION
著者Sankaranarayanan, R, Cherney, M.M, Cherney, L.T, Garen, C, Moradian, F, James, M.N.G, TB Structural Genomics Consortium (TBSGC)
登録日2007-03-07
公開日2007-07-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The crystal structures of ornithine carbamoyltransferase from Mycobacterium tuberculosis and its ternary complex with carbamoyl phosphate and L-norvaline reveal the enzyme's catalytic mechanism.
J.Mol.Biol., 375, 2008
2NQT
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Crystal structure of N-Acetyl-gamma-Glutamyl-Phosphate Reductase (Rv1652) from Mycobacterium tuberculosis at 1.58 A resolution
分子名称: N-acetyl-gamma-glutamyl-phosphate reductase
著者Cherney, L.T, Cherney, M.M, Garen, C.R, Moraidin, F, James, M.N.G, TB Structural Genomics Consortium (TBSGC)
登録日2006-10-31
公開日2006-11-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Crystal Structure of N-acetyl-gamma-glutamyl-phosphate Reductase from Mycobacterium tuberculosis in Complex with NADP(+).
J.Mol.Biol., 367, 2007
3LAP
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The Structure of the Intermediate Complex of the Arginine Repressor from Mycobacterium tuberculosis Bound to its DNA Operator and L-canavanine.
分子名称: 5'-D(*TP*TP*GP*CP*AP*TP*AP*AP*CP*GP*AP*TP*GP*CP*AP*A)-3', 5'-D(*TP*TP*GP*CP*AP*TP*CP*GP*TP*TP*AP*TP*GP*CP*AP*A)-3', Arginine repressor, ...
著者Cherney, L.T, Cherney, M.M, Garen, C.R, James, M.N.G, TB Structural Genomics Consortium (TBSGC)
登録日2010-01-06
公開日2010-05-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献crystal structure of the intermediate complex of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator reveals detailed mechanism of arginine repression.
J.Mol.Biol., 399, 2010
3LAJ
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The Structure of the Intermediate Complex of the Arginine Repressor from Mycobacterium tuberculosis Bound to its DNA Operator and L-arginine.
分子名称: 5'-D(*TP*TP*GP*CP*AP*TP*AP*AP*CP*GP*AP*TP*GP*CP*AP*A)-3', 5'-D(*TP*TP*GP*CP*AP*TP*CP*GP*TP*TP*AP*TP*GP*CP*AP*A)-3', ARGININE, ...
著者Cherney, L.T, Cherney, M.M, Garen, C.R, James, M.N.G, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2010-01-06
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.306 Å)
主引用文献crystal structure of the intermediate complex of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator reveals detailed mechanism of arginine repression.
J.Mol.Biol., 399, 2010
3MBI
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BU of 3mbi by Molmil
Crystal structure of the phosphoribosylpyrophosphate (PRPP) synthetase from Thermoplasma volcanium in complex with ADP-Mg2+ and ribose 5-phosphate
分子名称: 5-O-phosphono-alpha-D-ribofuranose, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Cherney, L.T, Cherney, M.M, Garen, C.R, James, M.N.G.
登録日2010-03-25
公開日2011-04-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structures of Thermoplasma volcanium phosphoribosyl pyrophosphate synthetase bound to ribose-5-phosphate and ATP analogs.
J.Mol.Biol., 413, 2011
3AAX
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BU of 3aax by Molmil
Crystal structure of probable thiosulfate sulfurtransferase cysa3 (RV3117) from Mycobacterium tuberculosis: monoclinic FORM
分子名称: Putative thiosulfate sulfurtransferase
著者Sankaranarayanan, R, Witholt, S.J, Cherney, M.M, Garen, C.R, Cherney, L.T, James, M.N.G, TB Structural Genomics Consortium (TBSGC)
登録日2009-11-28
公開日2009-12-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of probable thiosulfate sulfurtransferase CysA3 (Rv3117) from Mycobacterium tuberculosis
To be Published
4WL1
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Structure of WzzE Polysaccharide Co-polymerase
分子名称: Lipopolysaccharide biosynthesis protein WzzE
著者Kalynych, S, Cherney, M, Cygler, M.
登録日2014-10-05
公開日2014-10-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (5.989 Å)
主引用文献Quaternary structure of WzzB and WzzE polysaccharide copolymerases.
Protein Sci., 24, 2015
3AAY
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Crystal structure of probable thiosulfate sulfurtransferase CYSA3 (RV3117) from Mycobacterium tuberculosis: orthorhombic form
分子名称: GLYCEROL, Putative thiosulfate sulfurtransferase, SULFATE ION
著者Sankaranarayanan, R, Witholt, S.J, Cherney, M.M, Garen, C.R, Cherney, L.T, James, M.N.G, TB Structural Genomics Consortium (TBSGC)
登録日2009-11-28
公開日2009-12-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure of probable thiosulfate sulfurtransferase CysA3 (Rv3117) from Mycobacterium tuberculosis
To be Published
3BUE
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Crystal structure of the C-terminal domain hexamer of ArgR from Mycobacterium tuberculosis
分子名称: Arginine repressor ArgR
著者Cherney, L.T, Cherney, M.M, Garen, C.R, Lu, G.J, James, M.N.G, TB Structural Genomics Consortium (TBSGC)
登録日2008-01-02
公開日2008-01-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of the C-terminal domain of the arginine repressor protein from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 64, 2008
2ZFZ
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Crystal structure of the C-terminal domain hexamer of ArgR from Mycobacterium tuberculosis in complex with arginine
分子名称: ARGININE, Arginine repressor, GUANIDINE
著者Cherney, L.T, Cherney, M.M, Garen, C.R, Lu, G.J, James, M.N.G, TB Structural Genomics Consortium (TBSGC)
登録日2008-01-16
公開日2008-02-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of the C-terminal domain of the arginine repressor protein from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 64, 2008
4MU6
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BU of 4mu6 by Molmil
Crystal Structure of the N-terminal domain of Effector Protein LegC3 from Legionella pneumophila
分子名称: Kinectin 1 (Kinesin receptor)
著者Yao, D, Cherney, M, Cygler, M.
登録日2013-09-20
公開日2013-12-11
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.082 Å)
主引用文献Structure of the N-terminal domain of the effector protein LegC3 from Legionella pneumophila.
Acta Crystallogr.,Sect.D, 70, 2014
3CAG
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Crystal structure of the oligomerization domain hexamer of the arginine repressor protein from Mycobacterium tuberculosis in complex with 9 arginines.
分子名称: ARGININE, Arginine repressor
著者Cherney, L.T, Cherney, M.M, Garen, C.R, Lu, G.J, James, M.N.G, TB Structural Genomics Consortium (TBSGC)
登録日2008-02-19
公開日2008-03-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the C-terminal domain of the arginine repressor protein from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 64, 2008
1XXO
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BU of 1xxo by Molmil
X-ray crystal structure of mycobacterium tuberculosis pyridoxine 5'-phosphate oxidase at 1.8 a resolution
分子名称: hypothetical protein Rv1155
著者Biswal, B.K, Cherney, M.M, Wang, M, Garen, C, James, M.N.G, TB Structural Genomics Consortium (TBSGC)
登録日2004-11-07
公開日2004-11-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray crystal structure of mycobacterium tuberculosis pyridoxine 5'-phosphate oxidase at 1.8 a resolution
To be Published
1AVF
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ACTIVATION INTERMEDIATE 2 OF HUMAN GASTRICSIN FROM HUMAN STOMACH
分子名称: GASTRICSIN, SODIUM ION
著者Khan, A.R, Cherney, M.M, Tarasova, N.I, James, M.N.G.
登録日1997-09-16
公開日1998-02-25
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural characterization of activation 'intermediate 2' on the pathway to human gastricsin.
Nat.Struct.Biol., 4, 1997
1U32
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Crystal structure of a Protein Phosphatase-1: Calcineurin Hybrid Bound to Okadaic Acid
分子名称: BETA-MERCAPTOETHANOL, MANGANESE (II) ION, OKADAIC ACID, ...
著者Maynes, J.T, Perreault, K.R, Cherney, M.M, Luu, H.A, James, M.N.G, Holmes, C.F.B.
登録日2004-07-20
公開日2004-08-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure and Mutagenesis of a Protein Phosphatase-1:Calcineurin Hybrid Elucidate the Role of the {beta}12-{beta}13 Loop in Inhibitor Binding
J.Biol.Chem., 279, 2004
5JMD
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Heparinase III-BT4657 gene product, Methylated Lysines
分子名称: Heparinase III protein, MAGNESIUM ION
著者Ulaganathan, T.S, Shi, R, Yao, D, Garron, M.-L, Cherney, M, Cygler, M.
登録日2016-04-28
公開日2016-05-25
最終更新日2018-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Conformational flexibility of PL12 family heparinases: structure and substrate specificity of heparinase III from Bacteroides thetaiotaomicron (BT4657).
Glycobiology, 27, 2017
5JMF
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Heparinase III-BT4657 gene product
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Heparinase III protein, ...
著者Ulaganathan, T.S, Shi, R, Yao, D, Garron, M.-L, Cherney, M, Cygler, M.
登録日2016-04-28
公開日2016-05-25
最終更新日2018-01-17
実験手法X-RAY DIFFRACTION (1.854 Å)
主引用文献Conformational flexibility of PL12 family heparinases: structure and substrate specificity of heparinase III from Bacteroides thetaiotaomicron (BT4657).
Glycobiology, 27, 2017
3IT4
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The Crystal Structure of Ornithine Acetyltransferase from Mycobacterium tuberculosis (Rv1653) at 1.7 A
分子名称: ACETATE ION, Arginine biosynthesis bifunctional protein argJ alpha chain, Arginine biosynthesis bifunctional protein argJ beta chain, ...
著者Sankaranarayanan, R, Cherney, M.M, Garen, C, Garen, G, Yuan, M, James, M.N, TB Structural Genomics Consortium (TBSGC)
登録日2009-08-27
公開日2010-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The molecular structure of ornithine acetyltransferase from Mycobacterium tuberculosis bound to ornithine, a competitive inhibitor.
J.Mol.Biol., 397, 2010
3IT6
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The Crystal Structure of Ornithine Acetyltransferase complexed with Ornithine from Mycobacterium tuberculosis (Rv1653) at 2.4 A
分子名称: Arginine biosynthesis bifunctional protein argJ alpha chain, Arginine biosynthesis bifunctional protein argJ beta chain, L-ornithine
著者Sankaranarayanan, R, Cherney, M.M, Garen, C, Garen, G, Yuan, M, James, M.N, TB Structural Genomics Consortium (TBSGC)
登録日2009-08-27
公開日2010-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The molecular structure of ornithine acetyltransferase from Mycobacterium tuberculosis bound to ornithine, a competitive inhibitor.
J.Mol.Biol., 397, 2010

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