1U32

Crystal structure of a Protein Phosphatase-1: Calcineurin Hybrid Bound to Okadaic Acid

Summary for 1U32

Entry DOI	10.2210/pdb1u32/pdb
Descriptor	Serine/threonine protein phosphatase PP1-gamma catalytic subunit, MANGANESE (II) ION, OKADAIC ACID, ... (5 entities in total)
Functional Keywords	hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P36873
Total number of polymer chains	1
Total formula weight	34921.19
Authors	Maynes, J.T.,Perreault, K.R.,Cherney, M.M.,Luu, H.A.,James, M.N.G.,Holmes, C.F.B. (deposition date: 2004-07-20, release date: 2004-08-17, Last modification date: 2023-10-25)
Primary citation	Maynes, J.T.,Perreault, K.R.,Cherney, M.M.,Luu, H.A.,James, M.N.G.,Holmes, C.F.B. Crystal Structure and Mutagenesis of a Protein Phosphatase-1:Calcineurin Hybrid Elucidate the Role of the {beta}12-{beta}13 Loop in Inhibitor Binding J.Biol.Chem., 279:43198-43206, 2004 Cited by PubMed: 15280359 DOI: 10.1074/jbc.M407184200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation