3EKM

Crystal structure of diaminopimelate epimerase form arabidopsis thaliana in complex with irreversible inhibitor DL-AziDAP

Summary for 3EKM

• Entry DOI: 10.2210/pdb3ekm/pdb
• Related: 3EJX
• Descriptor: Diaminopimelate epimerase, chloroplastic, (2R,6S)-2,6-DIAMINO-2-METHYLHEPTANEDIOIC ACID (3 entities in total)
• Functional Keywords: diaminopimelate epimerase, arabidopsis, plp-independent amino acid racemase, aziridino-diaminopimelate, catalytic mechanism, isomerase
• Biological source: Arabidopsis thaliana (Mouse-ear cress)
• Cellular location: Plastid, chloroplast (Potential): Q9LFG2
• Total number of polymer chains: 6
• Total formula weight: 207066.31

Authors

Pillai, B.,Moorthie, V.A.,Cherney, M.M.,van Belkum, M.J.,Vederas, J.C.,James, M.N.G. (deposition date: 2008-09-19, release date: 2009-02-17, Last modification date: 2023-08-30)

• Primary citation: Pillai, B.,Moorthie, V.A.,van Belkum, M.J.,Marcus, S.L.,Cherney, M.M.,Diaper, C.M.,Vederas, J.C.,James, M.N.; Crystal structure of diaminopimelate epimerase from Arabidopsis thaliana, an amino acid racemase critical for L-lysine biosynthesis.; J.Mol.Biol., 385:580-594, 2009; PubMed: 19013471; DOI: 10.1016/j.jmb.2008.10.072

Experimental method

X-RAY DIFFRACTION (2.3 Å)