6IK4
 
 | | A Novel M23 Metalloprotease Pseudoalterin from Deep-sea | | Descriptor: | Elastinolytic metalloprotease, GLYCEROL, ZINC ION | | Authors: | Zhao, H.L, Tang, B.L, Yang, J, Chen, X.L, Zhang, Y.Z. | | Deposit date: | 2018-10-14 | | Release date: | 2019-10-16 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A predator-prey interaction between a marine Pseudoalteromonas sp. and Gram-positive bacteria.
Nat Commun, 11, 2020
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8FVJ
 | | Dimeric form of HIV-1 Vif in complex with human CBF-beta, ELOB, ELOC, and CUL5 | | Descriptor: | Core-binding factor subunit beta, Cullin-5, Elongin-B, ... | | Authors: | Ito, F, Alvarez-Cabrera, A.L, Zhou, Z.H, Chen, X.S. | | Deposit date: | 2023-01-19 | | Release date: | 2023-09-06 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.54 Å) | | Cite: | Structural basis of HIV-1 Vif-mediated E3 ligase targeting of host APOBEC3H.
Nat Commun, 14, 2023
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2H1L
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8HQP
 | | Crystal structure of AbHheG mutant from Acidimicrobiia bacterium | | Descriptor: | AbHheG_m | | Authors: | Zhou, C.H, Chen, X, Han, X, Liu, W.D, Wu, Q.Q, Zhu, D.M, Ma, Y.H. | | Deposit date: | 2022-12-13 | | Release date: | 2023-08-02 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Flipping the Substrate Creates a Highly Selective Halohydrin Dehalogenase for the Synthesis of Chiral 4-Aryl-2-oxazolidinones from Readily Available Epoxides
Acs Catalysis, 13, 2023
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6CXC
 | | 3.9A Cryo-EM structure of murine antibody bound at a novel epitope of respiratory syncytial virus fusion protein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, Envelope glycoprotein chimera, ... | | Authors: | Xie, Q, Wang, Z, Chen, X, Ni, F, Ma, J, Wang, Q. | | Deposit date: | 2018-04-02 | | Release date: | 2019-07-31 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structure basis of neutralization by a novel site II/IV antibody against respiratory syncytial virus fusion protein.
Plos One, 14, 2019
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6BVH
 | | Trypsin complexed with a modified sunflower trypsin inhibitor, SFTI-TCTR(N12,N14) | | Descriptor: | CALCIUM ION, Cationic trypsin, GLYCEROL, ... | | Authors: | Riley, B.T, Chen, X. | | Deposit date: | 2017-12-13 | | Release date: | 2018-12-19 | | Last modified: | 2019-01-30 | | Method: | X-RAY DIFFRACTION (1.927 Å) | | Cite: | Potent, multi-target serine protease inhibition achieved by a simplified beta-sheet motif.
PLoS ONE, 14, 2019
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6CKK
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7YDI
 | | SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2, focused refinement of RBD region | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of R1-32, Light chain of R1-32, ... | | Authors: | Liu, B, Gao, X, Li, Z, Chen, X, He, J, Chen, L, Xiong, X. | | Deposit date: | 2022-07-04 | | Release date: | 2022-08-24 | | Last modified: | 2023-07-26 | | Method: | ELECTRON MICROSCOPY (3.98 Å) | | Cite: | SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope.
Nat Microbiol, 7, 2022
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3G5C
 | | Structural and biochemical studies on the ectodomain of human ADAM22 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADAM 22, CALCIUM ION | | Authors: | Liu, H, Shim, A, Chen, X, He, X. | | Deposit date: | 2009-02-04 | | Release date: | 2009-08-18 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | Structural and biochemical studies on the ectodomain of human ADAM22
J.Biol.Chem., 2009
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3DWQ
 | | Crystal structure of the A-subunit of the AB5 toxin from E. coli with Neu5Gc-2,3Gal-1,3GlcNAc | | Descriptor: | AZIDE ION, N-PROPANOL, N-glycolyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ... | | Authors: | Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. | | Deposit date: | 2008-07-22 | | Release date: | 2008-11-04 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin
Nature, 456, 2008
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2E0H
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1WM7
 | | Solution Structure of BmP01 from the Venom of Scorpion Buthus martensii Karsch, 9 structures | | Descriptor: | Neurotoxin BmP01 | | Authors: | Wu, G, Li, Y, Wei, D, He, F, Jiang, S, Hu, G, Wu, H, Chen, X. | | Deposit date: | 2004-07-05 | | Release date: | 2004-07-27 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of BmP01 from the Venom of Scorpion Buthus martensii Karsch
Biochem.Biophys.Res.Commun., 276, 2000
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2EX1
 | | Crystal structure of mutifunctional sialyltransferase from Pasteurella multocida with CMP bound | | Descriptor: | CYTIDINE-5'-MONOPHOSPHATE, a2,3-sialyltransferase, a2,a6-sialyltransferase | | Authors: | Ni, L, Sun, M, Chen, X, Fisher, A.J. | | Deposit date: | 2005-11-07 | | Release date: | 2006-02-28 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Cytidine 5'-Monophosphate (CMP)-Induced Structural Changes in a Multifunctional Sialyltransferase from Pasteurella multocida
Biochemistry, 45, 2006
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2EX0
 | | Crystal structure of multifunctional sialyltransferase from Pasteurella Multocida | | Descriptor: | a2,3-sialyltransferase, a2,6-sialyltransferase | | Authors: | Ni, L, Sun, M, Chen, X, Fisher, A.J. | | Deposit date: | 2005-11-07 | | Release date: | 2006-02-28 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Cytidine 5'-Monophosphate (CMP)-Induced Structural Changes in a Multifunctional Sialyltransferase from Pasteurella multocida
Biochemistry, 45, 2006
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7FAT
 | | Structure Determination of the RBD-NB1A7 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, nb_1A7 | | Authors: | Geng, Y, Shi, Z.Z, Li, X.Y, Wang, L, Sun, Z.C, Zhang, H.W, Chen, X.C. | | Deposit date: | 2021-07-07 | | Release date: | 2022-05-18 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Structural basis of nanobodies neutralizing SARS-CoV-2 variants
Structure, 30, 2022
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7FAU
 | | Structure Determination of the NB1B11-RBD Complex | | Descriptor: | NB_1B11, Spike protein S1, ZINC ION | | Authors: | Shi, Z.Z, Li, X.X, Wang, L, Sun, Z.C, Zhang, H.W, Chen, X.C, Cui, Q.Q, Qiao, H.R, Lan, Z.Y, Zhang, X. | | Deposit date: | 2021-07-07 | | Release date: | 2022-06-01 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Structural basis of nanobodies neutralizing SARS-CoV-2 variants.
Structure, 30, 2022
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2HDC
 | | STRUCTURE OF TRANSCRIPTION FACTOR GENESIS/DNA COMPLEX | | Descriptor: | DNA (5'-D(P*GP*CP*TP*TP*AP*AP*AP*AP*TP*AP*AP*CP*AP*AP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*TP*TP*GP*TP*TP*AP*TP*TP*TP*TP*AP*AP*GP*C)-3'), PROTEIN (TRANSCRIPTION FACTOR) | | Authors: | Jin, C, Marsden, I, Chen, X, Liao, X. | | Deposit date: | 1999-05-05 | | Release date: | 1999-07-05 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Dynamic DNA contacts observed in the NMR structure of winged helix protein-DNA complex.
J.Mol.Biol., 289, 1999
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8H8Y
 | | Crystal structure of AbHheG from Acidimicrobiia bacterium | | Descriptor: | GLYCEROL, alpha/beta hydrolase | | Authors: | Zhou, C.H, Chen, X, Han, X, Liu, W.D, Wu, Q.Q, Zhu, D.M, Ma, Y.H. | | Deposit date: | 2022-10-24 | | Release date: | 2023-08-02 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Flipping the Substrate Creates a Highly Selective Halohydrin Dehalogenase for the Synthesis of Chiral 4-Aryl-2-oxazolidinones from Readily Available Epoxides
Acs Catalysis, 13, 2023
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3BGW
 | | The Structure Of A DnaB-Like Replicative Helicase And Its Interactions With Primase | | Descriptor: | DNAB-Like Replicative Helicase | | Authors: | Wang, G, Klein, M.G, Tokonzaba, E, Zhang, Y, Holden, L.G, Chen, X.S. | | Deposit date: | 2007-11-27 | | Release date: | 2007-12-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.91 Å) | | Cite: | The structure of a DnaB-family replicative helicase and its interactions with primase.
Nat.Struct.Mol.Biol., 15, 2008
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3DWA
 | | Crystal structure of the B-subunit of the AB5 toxin from E. coli | | Descriptor: | PENTAETHYLENE GLYCOL, Subtilase cytotoxin, subunit B | | Authors: | Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. | | Deposit date: | 2008-07-22 | | Release date: | 2008-11-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.084 Å) | | Cite: | Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin
Nature, 456, 2008
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3DWP
 | | Crystal structure of the B-subunit of the AB5 toxin from E. Coli with Neu5Gc | | Descriptor: | N-glycolyl-alpha-neuraminic acid, PENTAETHYLENE GLYCOL, Subtilase cytotoxin, ... | | Authors: | Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. | | Deposit date: | 2008-07-22 | | Release date: | 2008-11-04 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin
Nature, 456, 2008
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3E1U
 | | The Crystal Structure of the Anti-Viral APOBEC3G Catalytic Domain | | Descriptor: | DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION | | Authors: | Holden, L, Prochnow, C, Chang, Y.P, Bransteitter, R, Chelico, L, Sen, U, Stevens, R.C, Goodman, R.F, Chen, X.S. | | Deposit date: | 2008-08-04 | | Release date: | 2008-10-07 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications.
Nature, 456, 2008
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3IQS
 | | Crystal structure of the anti-viral APOBEC3G catalytic domain | | Descriptor: | DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION | | Authors: | Holden, L.G, Prochnow, C, Chang, Y.P, Bransteitter, R, Chelico, L, Sen, U, Stevens, R.C, Goodman, R.F, Chen, X.S. | | Deposit date: | 2009-08-20 | | Release date: | 2009-11-10 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications.
Nature, 456, 2008
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3BH0
 | | ATPase Domain of G40P | | Descriptor: | DNAB-LIKE REPLICATIVE HELICASE | | Authors: | Wang, G, Klein, M.G, Tokonzaba, E, Zhang, Y, Holden, L.G, Chen, X.S. | | Deposit date: | 2007-11-27 | | Release date: | 2007-12-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | The structure of a DnaB-family replicative helicase and its interactions with primase.
Nat.Struct.Mol.Biol., 15, 2008
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7E6T
 | | Structural insights into the activation of human calcium-sensing receptor | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CYCLOMETHYLTRYPTOPHAN, ... | | Authors: | Geng, Y, Chen, X.C, Wang, L, Cui, Q.Q, Ding, Z.Y, Han, L, Kou, Y.J, Zhang, W.Q, Wang, H.N, Jia, X.M, Dai, M, Shi, Z.Z, Li, Y.Y, Li, X.Y. | | Deposit date: | 2021-02-24 | | Release date: | 2021-09-22 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insights into the activation of human calcium-sensing receptor.
Elife, 10, 2021
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