6BVH
Trypsin complexed with a modified sunflower trypsin inhibitor, SFTI-TCTR(N12,N14)
Summary for 6BVH
Entry DOI | 10.2210/pdb6bvh/pdb |
Descriptor | Cationic trypsin, Trypsin inhibitor 1, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | protease inhibitor complex, sunflower trypsin inhibitor, sfti, hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Bos taurus (Bovine) More |
Total number of polymer chains | 2 |
Total formula weight | 25494.63 |
Authors | Riley, B.T.,Chen, X. (deposition date: 2017-12-13, release date: 2018-12-19, Last modification date: 2019-01-30) |
Primary citation | Chen, X.,Riley, B.T.,de Veer, S.J.,Hoke, D.E.,Van Haeften, J.,Leahy, D.,Swedberg, J.E.,Brattsand, M.,Hartfield, P.J.,Buckle, A.M.,Harris, J.M. Potent, multi-target serine protease inhibition achieved by a simplified beta-sheet motif. PLoS ONE, 14:e0210842-e0210842, 2019 Cited by PubMed: 30668585DOI: 10.1371/journal.pone.0210842 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.927 Å) |
Structure validation
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