Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004175 | molecular_function | endopeptidase activity |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007586 | biological_process | digestion |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0097180 | cellular_component | serine protease inhibitor complex |
| A | 0097655 | molecular_function | serpin family protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 301 |
| Chain | Residue |
| A | GLU70 |
| A | ASN72 |
| A | VAL75 |
| A | GLU80 |
| A | HOH408 |
| A | HOH505 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 302 |
| Chain | Residue |
| A | PHE181 |
| A | GLN210 |
| A | LYS230 |
| A | HOH433 |
| A | HOH557 |
| A | CYS128 |
| A | ALA129 |
| A | ILE162 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue GOL A 303 |
| Chain | Residue |
| A | ASN34 |
| A | TYR39 |
| A | HIS40 |
| A | ARG66 |
| A | ILE73 |
| A | ASN74 |
| A | SER164 |
| A | SER166 |
| A | SER167 |
| A | SO4305 |
| A | HOH478 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 304 |
| Chain | Residue |
| A | GLN135 |
| A | CYS136 |
| A | LYS159 |
| A | VAL200 |
| A | CYS201 |
| A | SER202 |
| A | GLY203 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 305 |
| Chain | Residue |
| A | ARG66 |
| A | SER166 |
| A | SER167 |
| A | SER170 |
| A | GOL303 |
| A | HOH403 |
| A | HOH424 |
| A | HOH530 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 306 |
| Chain | Residue |
| A | ALA129 |
| A | SER130 |
| A | THR134 |
| A | SER202 |
| A | HOH405 |
| A | HOH415 |
| A | HOH432 |
| A | HOH600 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 307 |
| Chain | Residue |
| A | LYS169 |
| A | PRO173 |
| A | GLY174 |
| A | GLN240 |
| A | HOH466 |
| A | HOH560 |
| A | HOH562 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | binding site for residue GOL I 101 |
| Chain | Residue |
| A | HIS57 |
| A | TYR59 |
| A | LYS60 |
| I | SER6 |
| I | PRO8 |
| I | ILE10 |
| I | HOH201 |
| I | HOH205 |
| I | HOH208 |
| I | HOH209 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 220 |
| Details | Domain: {"description":"Peptidase S1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00274","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 13 |
| Details | Peptide: {"description":"Trypsin inhibitor 1","featureId":"PRO_0000042673"} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Site: {"description":"Reactive bond","evidences":[{"source":"UniProtKB","id":"P81705","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Cyclopeptide (Gly-Asp)"} |
