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PDB: 982 件
1BOO
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PVUII DNA METHYLTRANSFERASE (CYTOSINE-N4-SPECIFIC)
分子名称: PROTEIN (N-4 CYTOSINE-SPECIFIC METHYLTRANSFERASE PVU II), S-ADENOSYL-L-HOMOCYSTEINE
著者Gong, W, O'Gara, M, Blumenthal, R.M, Cheng, X.
登録日1998-07-31
公開日1998-08-12
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of pvu II DNA-(cytosine N4) methyltransferase, an example of domain permutation and protein fold assignment.
Nucleic Acids Res., 25, 1997
1MR3
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Saccharomyces cerevisiae ADP-ribosylation Factor 2 (ScArf2) complexed with GDP-3'P at 1.6A resolution
分子名称: 1,2-ETHANEDIOL, 1,3-PROPANDIOL, ADP-ribosylation factor 2, ...
著者Amor, J.-C, Horton, J.R, Zhu, X, Wang, Y, Sullards, C, Ringe, D, Cheng, X, Kahn, R.A.
登録日2002-09-17
公開日2002-11-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structures of yeast ARF2 and ARL1: distinct roles for the N terminus in the structure and function of ARF family GTPases.
J.Biol.Chem., 276, 2001
1G55
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Structure of human DNMT2, an enigmatic DNA methyltransferase homologue
分子名称: BETA-MERCAPTOETHANOL, DNA CYTOSINE METHYLTRANSFERASE DNMT2, GLYCEROL, ...
著者Dong, A, Yoder, J.A, Zhang, X, Zhou, L, Bestor, T.H, Cheng, X.
登録日2000-10-30
公開日2001-01-17
最終更新日2018-06-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA.
Nucleic Acids Res., 29, 2001
1MVX
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structure of the SET domain histone lysine methyltransferase Clr4
分子名称: CRYPTIC LOCI REGULATOR 4, NICKEL (II) ION, SULFATE ION, ...
著者Min, J.R, Zhang, X, Cheng, X.D, Grewal, S.I.S, Xu, R.-M.
登録日2002-09-26
公開日2002-10-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the SET domain histone lysine methyltransferase Clr4.
Nat.Struct.Biol., 9, 2002
5CG9
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NgTET1 in complex with 5mC DNA in space group P3221
分子名称: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, DNA (5'-D(*TP*GP*TP*CP*AP*GP*(5CM)P*GP*CP*AP*TP*GP*G)-3'), ...
著者Hashimoto, H, Pais, J.E, Dai, N, Zhang, X, Zheng, Y, Cheng, X.
登録日2015-07-09
公開日2015-09-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.693 Å)
主引用文献Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA.
Nucleic Acids Res., 43, 2015
5CG8
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NgTET1 in complex with 5hmC DNA
分子名称: 2-OXOGLUTARIC ACID, DNA (5'-D(*AP*GP*AP*AP*TP*TP*CP*CP*GP*TP*TP*CP*CP*A)-3'), DNA (5'-D(*TP*GP*GP*AP*AP*(5HC)P*GP*GP*AP*AP*TP*TP*CP*T)-3'), ...
著者Hashimoto, H, Pais, J.E, Dai, N, Zhang, X, Zheng, Y, Cheng, X.
登録日2015-07-09
公開日2015-09-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA.
Nucleic Acids Res., 43, 2015
7CZ5
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Cryo-EM structure of the human growth hormone-releasing hormone receptor-Gs protein complex
分子名称: CHOLESTEROL, Growth hormone-releasing hormone receptor,growth hormone-releasing hormone receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zhou, F, Zhang, H, Cong, Z, Zhao, L, Zhou, Q, Mao, C, Cheng, X, Shen, D, Cai, X, Ma, C, Wang, Y, Dai, A, Zhou, Y, Sun, W, Zhao, F, Zhao, S, Jiang, H, Jiang, Y, Yang, D, Xu, H.E, Zhang, Y, Wang, M.
登録日2020-09-07
公開日2020-11-18
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis for activation of the growth hormone-releasing hormone receptor.
Nat Commun, 11, 2020
7C37
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Crystal structure of AofleA from Arthrobotrys oligospora
分子名称: AofleA, BICINE
著者Liu, M, Cheng, X, Wang, J, Zhang, M, Wang, M.
登録日2020-05-11
公開日2020-07-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献Structural insights into the fungi-nematodes interaction mediated by fucose-specific lectin AofleA from Arthrobotrys oligospora.
Int.J.Biol.Macromol., 164, 2020
4JGC
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Human TDG N140A mutant IN A COMPLEX WITH 5-carboxylcytosine (5caC)
分子名称: 4-amino-2-oxo-1,2-dihydropyrimidine-5-carboxylic acid, G/T mismatch-specific thymine DNA glycosylase, oligonucleotide, ...
著者Hashimoto, H, Zhang, X, Cheng, X.
登録日2013-02-28
公開日2013-05-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.582 Å)
主引用文献Activity and crystal structure of human thymine DNA glycosylase mutant N140A with 5-carboxylcytosine DNA at low pH.
Dna Repair, 12, 2013
16VP
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CONSERVED CORE OF THE HERPES SIMPLEX VIRUS TRANSCRIPTIONAL REGULATORY PROTEIN VP16
分子名称: PROTEIN (VP16, VMW65, ATIF), ...
著者Liu, Y, Gong, W, Huang, C.C, Herr, W, Cheng, X.
登録日1999-02-11
公開日1999-07-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the conserved core of the herpes simplex virus transcriptional regulatory protein VP16.
Genes Dev., 13, 1999
1F0O
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PVUII ENDONUCLEASE/COGNATE DNA COMPLEX (GLUTARALDEHYDE-CROSSLINKED CRYSTAL) AT PH 7.5 WITH TWO CALCIUM IONS AT EACH ACTIVE SITE
分子名称: (5'-D(*TP*GP*AP*CP*CP*AP*GP*CP*TP*GP*GP*TP*C-3'), CALCIUM ION, TYPE II RESTRICTION ENZYME PVUII
著者Horton, J.R, Cheng, X.
登録日2000-05-16
公開日2000-11-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献PvuII endonuclease contains two calcium ions in active sites.
J.Mol.Biol., 300, 2000
1PEG
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Structural basis for the product specificity of histone lysine methyltransferases
分子名称: Histone H3, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ...
著者Zhang, X, Yang, Z, Khan, S.I, Horton, J.R, Tamaru, H, Selker, E.U, Cheng, X.
登録日2003-05-21
公開日2003-08-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structural basis for the product specificity of histone lysine methyltransferases
Mol.Cell, 12, 2003
7C3D
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Crystal structure of AofleA from Arthrobotrys oligospora in complex with D-arabinose
分子名称: AofleA, GLYCEROL, alpha-D-arabinopyranose, ...
著者Liu, M, Cheng, X, Wang, J, Zhang, M, Wang, M.
登録日2020-05-12
公開日2020-07-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.596 Å)
主引用文献Structural insights into the fungi-nematodes interaction mediated by fucose-specific lectin AofleA from Arthrobotrys oligospora.
Int.J.Biol.Macromol., 164, 2020
8KC6
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BU of 8kc6 by Molmil
X-ray structure of 3-alpha-(Or 20-beta)-hydroxysteroid dehydrogenase
分子名称: 3-alpha-(Or 20-beta)-hydroxysteroid dehydrogenase
著者Song, S.K, Lv, D.Q, Cheng, X.Y, Ma, Q.Q, Hu, Y.L, Su, Z.D.
登録日2023-08-06
公開日2023-08-30
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献X-ray structure of 3-alpha-(Or 20-beta)-hydroxysteroid dehydrogenase
To Be Published
2PVI
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BU of 2pvi by Molmil
PVUII ENDONUCLEASE COMPLEXED TO AN IODINATED COGNATE DNA
分子名称: DNA (5'-D(*TP*GP*AP*CP*CP*AP*GP*(C38)P*TP*GP*GP*TP*C)-3'), TYPE II RESTRICTION ENZYME PVUII
著者Horton, J, Cheng, X.
登録日1998-11-01
公開日1999-12-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献How is modification of the DNA substrate recognized by the PvuII restriction endonuclease?
J.Biol.Chem., 379, 1998
7C3C
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Crystal structure of AofleA from Arthrobotrys oligospora in complex with D-manose
分子名称: AofleA, GLYCEROL, alpha-D-mannopyranose, ...
著者Liu, M, Cheng, X, Wang, J, Zhang, M, Wang, M.
登録日2020-05-12
公開日2020-07-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.301 Å)
主引用文献Structural insights into the fungi-nematodes interaction mediated by fucose-specific lectin AofleA from Arthrobotrys oligospora.
Int.J.Biol.Macromol., 164, 2020
2ZO1
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Mouse NP95 SRA domain DNA specific complex 2
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*DGP*DTP*DCP*DAP*DGP*(5CM)P*DGP*DCP*DAP*DAP*DTP*DGP*DG)-3'), DNA (5'-D(*DTP*DCP*DCP*DAP*DTP*DGP*DCP*DGP*DCP*DTP*DGP*DAP*DC)-3'), ...
著者Hashimoto, H, Horton, J.R, Cheng, X.
登録日2008-05-05
公開日2008-09-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix
Nature, 455, 2008
2ZO0
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mouse NP95 SRA domain DNA specific complex 1
分子名称: DNA (5'-D(*DGP*DTP*DCP*DAP*DGP*(5CM)P*DGP*DCP*DAP*DAP*DTP*DGP*DG)-3'), DNA (5'-D(*DTP*DCP*DCP*DAP*DTP*DGP*DCP*DGP*DCP*DTP*DGP*DAP*DC)-3'), E3 ubiquitin-protein ligase UHRF1
著者Hashimoto, H, Horton, J.R, Cheng, X.
登録日2008-05-05
公開日2008-09-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix
Nature, 455, 2008
1U2Z
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Crystal structure of histone K79 methyltransferase Dot1p from yeast
分子名称: Histone-lysine N-methyltransferase, H3 lysine-79 specific, S-ADENOSYL-L-HOMOCYSTEINE
著者Sawada, K, Yang, Z, Horton, J.R, Collins, R.E, Zhang, X, Cheng, X.
登録日2004-07-20
公開日2004-09-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase
J.Biol.Chem., 279, 2004
1EYU
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HIGH RESOLUTION STRUCTURE OF THE PVUII ENDONCULEASE/COGNATE DNA COMPLEX AT PH 4.6
分子名称: DNA (5'-D(*TP*GP*AP*CP*CP*AP*GP*CP*TP*GP*GP*TP*C)-3'), TYPE II RESTRICTION ENZYME PVUII
著者Horton, J.R, Cheng, X.
登録日2000-05-09
公開日2000-07-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献PvuII endonuclease contains two calcium ions in active sites.
J.Mol.Biol., 300, 2000
1ORH
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Structure of the Predominant Protein Arginine Methyltransferase PRMT1
分子名称: GLYCEROL, Protein arginine N-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Zhang, X, Cheng, X.
登録日2003-03-13
公開日2003-08-26
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structure of the Predominant Protein Arginine Methyltransferase PRMT1 and Analysis of Its Binding to Substrate Peptides
Structure, 11, 2003
1ORI
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Structure of the predominant protein arginine methyltransferase PRMT1
分子名称: Protein arginine N-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, UNKNOWN LIGAND
著者Zhang, X, Cheng, X.
登録日2003-03-13
公開日2003-05-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the Predominant Protein Arginine Methyltransferase PRMT1 and Analysis of its Binding to Substrate Peptides
Structure, 11, 2003
5X0W
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Molecular mechanism for the binding between Sharpin and HOIP
分子名称: E3 ubiquitin-protein ligase RNF31, Sharpin
著者Liu, J, Li, F, Cheng, X, Pan, L.
登録日2017-01-23
公開日2017-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Insights into SHARPIN-Mediated Activation of HOIP for the Linear Ubiquitin Chain Assembly
Cell Rep, 21, 2017
3PVI
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D34G MUTANT OF PVUII ENDONUCLEASE COMPLEXED WITH COGNATE DNA SHOWS THAT ASP34 IS DIRECTLY INVOLVED IN DNA RECOGNITION AND INDIRECTLY INVOLVED IN CATALYSIS
分子名称: DNA (5'-D(*TP*GP*AP*CP*CP*AP*GP*CP*TP*GP*GP*TP*C)-3'), PROTEIN (PVUII ENDONUCLEASE)
著者Horton, J.R, Cheng, X.
登録日1998-10-09
公開日1998-10-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Asp34 of PvuII endonuclease is directly involved in DNA minor groove recognition and indirectly involved in catalysis.
J.Mol.Biol., 284, 1998
1Q0S
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Binary Structure of T4DAM with AdoHcy
分子名称: DNA adenine methylase, S-ADENOSYL-L-HOMOCYSTEINE
著者Yang, Z, Horton, J.R, Zhou, L, Zhang, X.J, Dong, A, Zhang, X, Schlagman, S.L, Kossykh, V, Hattman, S, Cheng, X.
登録日2003-07-17
公開日2003-09-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the bacteriophage T4 DNA adenine methyltransferase
Nat.Struct.Biol., 10, 2003

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