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PDB: 426 件
5H64
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Cryo-EM structure of mTORC1
分子名称: Regulatory-associated protein of mTOR, Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8
著者Yang, H, Wang, J, Liu, M, Chen, X, Huang, M, Tan, D, Dong, M, Wong, C.C.L, Wang, J, Xu, Y, Wang, H.
登録日2016-11-10
公開日2017-01-25
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献4.4 angstrom Resolution Cryo-EM structure of human mTOR Complex 1
Protein Cell, 7, 2016
5IHZ
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BU of 5ihz by Molmil
Crystal structure of anti-gliadin 1002-1E01 Fab fragment
分子名称: 1E01 Fab fragment heavy chain, 1E01 Fab fragment light chain
著者Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M.
登録日2016-03-01
公開日2017-03-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
JCI Insight, 2, 2017
5IG7
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BU of 5ig7 by Molmil
Crystal structure of anti-gliadin 1002-1E01 Fab fragment in complex of peptide PLQPQQPFP
分子名称: 1E01 Fab fragment heavy chain, 1E01 Fab fragment light chain, SULFATE ION, ...
著者Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M.
登録日2016-02-27
公開日2017-03-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
JCI Insight, 2, 2017
5IK3
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BU of 5ik3 by Molmil
Crystal structure of anti-gliadin 1002-1E03 Fab fragment
分子名称: 1E03 Fab fragment heavy chain, 1E03 Fab fragment light chain, SULFATE ION
著者Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M.
登録日2016-03-03
公開日2017-03-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
JCI Insight, 2, 2017
5IJK
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BU of 5ijk by Molmil
Crystal structure of anti-gliadin 1002-1E03 Fab fragment in complex of peptide PLQPEQPFP
分子名称: 1E03 Fab fragment heavy chain, 1E03 Fab fragment light chain, SULFATE ION, ...
著者Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M.
登録日2016-03-02
公開日2017-03-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
JCI Insight, 2, 2017
5IFJ
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BU of 5ifj by Molmil
Crystal structure of anti-gliadin 1002-1E01 Fab fragment in complex of peptide PLQPEQPFP
分子名称: 1E01 Fab fragment heavy chain, 1E01 Fab fragment light chain, SULFATE ION, ...
著者Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M.
登録日2016-02-26
公開日2017-03-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
JCI Insight, 2, 2017
4IAN
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BU of 4ian by Molmil
Crystal Structure of apo Human PRPF4B kinase domain
分子名称: SULFATE ION, Serine/threonine-protein kinase PRP4 homolog
著者Mechin, I, Haas, K, Chen, X, Zhang, Y, McLean, L.
登録日2012-12-06
公開日2013-08-28
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches.
J.Biol.Chem., 288, 2013
4IFC
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BU of 4ifc by Molmil
Crystal Structure of ADP-bound Human PRPF4B kinase domain
分子名称: ADENOSINE-5'-DIPHOSPHATE, SULFATE ION, Serine/threonine-protein kinase PRP4 homolog
著者Mechin, I, Haas, K, Chen, X, Zhang, Y, McLean, L.
登録日2012-12-14
公開日2013-08-28
最終更新日2013-11-06
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches.
J.Biol.Chem., 288, 2013
4IJP
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BU of 4ijp by Molmil
Crystal Structure of Human PRPF4B kinase domain in complex with 4-{5-[(2-Chloro-pyridin-4-ylmethyl)-carbamoyl]-thiophen-2-yl}-benzo[b]thiophene-2-carboxylic acid amine
分子名称: 4-(5-{[(2-chloropyridin-4-yl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide, SULFATE ION, Serine/threonine-protein kinase PRP4 homolog
著者Mechin, I, Haas, K, Chen, X, Zhang, Y, McLean, L.
登録日2012-12-22
公開日2013-08-28
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches.
J.Biol.Chem., 288, 2013
4ICK
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BU of 4ick by Molmil
Crystal structure of human AP4A hydrolase E58A mutant
分子名称: Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical], GLYCEROL, MAGNESIUM ION, ...
著者Ge, H, Chen, X.
登録日2012-12-10
公開日2013-12-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of wild-type and mutant human Ap4A hydrolase.
Biochem.Biophys.Res.Commun., 432, 2013
4IJX
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BU of 4ijx by Molmil
Crystal structure of human Ap4A hydrolase E58A mutant complexed with DPO
分子名称: Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical], DIPHOSPHATE, GLYCEROL, ...
著者Ge, H, Chen, X.
登録日2012-12-24
公開日2013-03-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of wild-type and mutant human Ap4A hydrolase.
Biochem.Biophys.Res.Commun., 432, 2013
4IIR
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BU of 4iir by Molmil
Crystal Structure of AMPPNP-bound Human PRPF4B kinase domain
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION, ...
著者Mechin, I, Haas, K, Chen, X, Zhang, Y, McLean, L.
登録日2012-12-20
公開日2013-08-28
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches.
J.Biol.Chem., 288, 2013
7ET0
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BU of 7et0 by Molmil
Crystal structure of the complex formed by Wolbachia cytoplasmic incompatibility factors CinA and CinB from wPip
分子名称: Bacteria factor A, Bacteria factor B
著者Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T.
登録日2021-05-12
公開日2021-11-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors.
Proc.Natl.Acad.Sci.USA, 118, 2021
7ESX
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BU of 7esx by Molmil
Crystal structure of Wolbachia cytoplasmic incompatibility factor CidA from wPip
分子名称: Bacteria factor 1
著者Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T.
登録日2021-05-12
公開日2021-11-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors.
Proc.Natl.Acad.Sci.USA, 118, 2021
7ESZ
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BU of 7esz by Molmil
Crystal structure of the complex formed by Wolbachia cytoplasmic incompatibility factors CinA and CinB with Mn2+ from wPip
分子名称: BACTERIA FACTOR A, BACTERIA FACTOR B, MANGANESE (II) ION
著者Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T.
登録日2021-05-12
公開日2021-11-10
実験手法X-RAY DIFFRACTION (2.476 Å)
主引用文献Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors.
Proc.Natl.Acad.Sci.USA, 118, 2021
7ESY
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BU of 7esy by Molmil
Crystal structure of the complex formed by Wolbachia cytoplasmic incompatibility factors CidA and CidBND1-ND2 from wPip
分子名称: Bacteria factor 1, CALCIUM ION, ULP_PROTEASE domain-containing protein
著者Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T.
登録日2021-05-12
公開日2021-11-10
実験手法X-RAY DIFFRACTION (2.297 Å)
主引用文献Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors.
Proc.Natl.Acad.Sci.USA, 118, 2021
4KNB
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BU of 4knb by Molmil
C-Met in complex with OSI ligand
分子名称: 7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine, GAMMA-BUTYROLACTONE, Hepatocyte growth factor receptor
著者Wang, J, Steinig, A.G, Li, A.H, Chen, X, Dong, H, Ferraro, C, Jin, M, Kadalbajoo, M, Kleinberg, A, Stolz, K.M, Tavares-Greco, P.A, Wang, T, Albertella, M.R, Peng, Y, Crew, L, Kahler, J.
登録日2013-05-09
公開日2014-04-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Novel 6-aminofuro[3,2-c]pyridines as potent, orally efficacious inhibitors of cMET and RON kinases.
Bioorg.Med.Chem.Lett., 23, 2013
6L03
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BU of 6l03 by Molmil
structure of PTP-MEG2 and MUNC18-1-pY145 peptide complex
分子名称: Tyrosine-protein phosphatase non-receptor type 9, stxbp1-pY145 peptide
著者Xu, Y.F, Chen, X, Yu, X, Sun, J.P.
登録日2019-09-25
公開日2020-09-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.084 Å)
主引用文献PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates.
Embo Rep., 22, 2021
6KZQ
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BU of 6kzq by Molmil
structure of PTP-MEG2 and NSF-pY83 peptide complex
分子名称: NSF-pY83 peptide, Tyrosine-protein phosphatase non-receptor type 9
著者Xu, Y.F, Chen, X, Yu, X, Sun, J.P.
登録日2019-09-25
公開日2020-09-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates.
Embo Rep., 22, 2021
4NKJ
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BU of 4nkj by Molmil
Structure of influenza B virus hemagglutinin at membrane fusion pH
分子名称: Hemagglutinin HA2
著者Ni, F, Chen, X, Shen, J, Wang, Q.
登録日2013-11-12
公開日2014-04-02
実験手法X-RAY DIFFRACTION (2.4535 Å)
主引用文献Structural insights into the membrane fusion mechanism mediated by influenza virus hemagglutinin.
Biochemistry, 53, 2014
6L6H
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BU of 6l6h by Molmil
Crystal structure of Lpg0189
分子名称: ACETATE ION, GLYCEROL, Uncharacterized protein Lpg0189
著者Ge, H, Chen, X.
登録日2019-10-29
公開日2019-11-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.403 Å)
主引用文献Crystal structure of a hypothetical T2SS effector Lpg0189 from Legionella pneumophila reveals a novel protein fold.
Biochem.Biophys.Res.Commun., 521, 2020
6L6G
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BU of 6l6g by Molmil
Crystal structure of SeMet_Lpg0189
分子名称: GLYCEROL, Uncharacterized protein Lpg0189
著者Ge, H, Chen, X.
登録日2019-10-29
公開日2019-11-27
最終更新日2020-01-15
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Crystal structure of a hypothetical T2SS effector Lpg0189 from Legionella pneumophila reveals a novel protein fold.
Biochem.Biophys.Res.Commun., 521, 2020
5Z9X
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BU of 5z9x by Molmil
Arabidopsis SMALL RNA DEGRADING NUCLEASE 1 in complex with an RNA substrate
分子名称: MAGNESIUM ION, RNA (5'-R(P*GP*CP*CP*CP*AP*UP*UP*AP*G)-3'), SULFATE ION, ...
著者Chen, J, Liu, L, You, C, Gu, J, Ruan, W, Zhang, L, Gan, J, Cao, C, Huang, Y, Chen, X, Ma, J.
登録日2018-02-05
公開日2018-06-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1.
Nat Commun, 9, 2018
5Z9Z
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BU of 5z9z by Molmil
The C-terminal RRM domain of Arabidopsis SMALL RNA DEGRADING NUCLEASE 1 (E329A/E330A/E332A)
分子名称: CITRATE ANION, Small RNA degrading nuclease 1
著者Chen, J, Liu, L, You, C, Gu, J, Ruan, W, Zhang, L, Cao, C, Gan, J, Huang, Y, Chen, X, Ma, J.
登録日2018-02-05
公開日2018-06-27
最終更新日2018-10-03
実験手法X-RAY DIFFRACTION (2.049 Å)
主引用文献Structural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1.
Nat Commun, 9, 2018
5ZQZ
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BU of 5zqz by Molmil
Structure of human mitochondrial trifunctional protein, tetramer
分子名称: Trifunctional enzyme subunit alpha, mitochondrial, Trifunctional enzyme subunit beta
著者Liang, K, Li, N, Dai, J, Wang, X, Liu, P, Chen, X, Wang, C, Gao, N, Xiao, J.
登録日2018-04-20
公開日2018-06-20
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM structure of human mitochondrial trifunctional protein
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

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