2Z59
| Complex Structures of Mouse Rpn13 (22-130aa) and ubiquitin | 分子名称: | Protein ADRM1, Ubiquitin | 著者 | Chen, X, Schreiner, P, Groll, M, Walters, K.J. | 登録日 | 2007-07-01 | 公開日 | 2008-05-20 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction. Nature, 453, 2008
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6MUN
| Structure of hRpn10 bound to UBQLN2 UBL | 分子名称: | 26S proteasome non-ATPase regulatory subunit 4, Ubiquilin-2 | 著者 | Chen, X, Walters, K.J. | 登録日 | 2018-10-23 | 公開日 | 2019-09-04 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of hRpn10 Bound to UBQLN2 UBL Illustrates Basis for Complementarity between Shuttle Factors and Substrates at the Proteasome. J.Mol.Biol., 431, 2019
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5IRS
| crystal structure of the proteasomal Rpn13 PRU-domain | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Proteasomal ubiquitin receptor ADRM1 | 著者 | Chen, X, Shi, K, Walters, K, Aihara, H. | 登録日 | 2016-03-14 | 公開日 | 2016-07-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.796 Å) | 主引用文献 | Structures of Rpn1 T1:Rad23 and hRpn13:hPLIC2 Reveal Distinct Binding Mechanisms between Substrate Receptors and Shuttle Factors of the Proteasome. Structure, 24, 2016
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6OER
| Cryo-EM structure of mouse RAG1/2 NFC complex (DNA2) | 分子名称: | CALCIUM ION, DNA (46-MER), DNA (57-MER), ... | 著者 | Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. | 登録日 | 2019-03-27 | 公開日 | 2020-01-29 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | 主引用文献 | Cutting antiparallel DNA strands in a single active site. Nat.Struct.Mol.Biol., 27, 2020
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2H6O
| Epstein Barr Virus Major Envelope Glycoprotein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Major outer envelope glycoprotein gp350, ... | 著者 | Chen, X.S. | 登録日 | 2006-05-31 | 公開日 | 2006-10-31 | 最終更新日 | 2021-02-03 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structure of the Epstein-Barr virus major envelope glycoprotein Nat.Struct.Mol.Biol., 13, 2006
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8JAI
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7F3M
| Crystal structure of FGFR4 kinase domain with PRN1371 | 分子名称: | 6-[2,6-bis(chloranyl)-3,5-dimethoxy-phenyl]-2-(methylamino)-8-[3-(4-prop-2-enoylpiperazin-1-yl)propyl]pyrido[2,3-d]pyrimidin-7-one, Fibroblast growth factor receptor 4, SULFATE ION | 著者 | Chen, X.J, Qu, L.Z, Dai, S.Y, Wei, H.D, Chen, Y.H. | 登録日 | 2021-06-16 | 公開日 | 2022-01-12 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.289 Å) | 主引用文献 | Structural insights into the potency and selectivity of covalent pan-FGFR inhibitors Commun Chem, 5, 2022
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6KUZ
| E.coli beta-galactosidase (E537Q) in complex with fluorescent probe KSL01 | 分子名称: | 3-(1,3-benzothiazol-2-yl)-2-[[4-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]methoxy]-5-methyl-benzaldehyde, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | 著者 | Chen, X, Hu, Y.L, Li, X.K, Guo, Y, Li, J. | 登録日 | 2019-09-03 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | 主引用文献 | First-generation species-selective chemical probes for fluorescence imaging of human senescence-associated beta-galactosidase. Chem Sci, 11, 2020
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7X9E
| Crystal structure of the 76E1 Fab in complex with a SARS-CoV-2 spike peptide | 分子名称: | 76E1 Fab Heavy Chain, 76E1 Fab Light Chain, Spike peptide | 著者 | Chen, X, Zhang, T, Ding, J, Sun, X, Sun, B. | 登録日 | 2022-03-15 | 公開日 | 2022-05-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2. Nat Microbiol, 7, 2022
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6IHG
| N terminal domain of Mycobacterium avium complex Lon protease | 分子名称: | Lon protease | 著者 | Chen, X.Y, Zhang, S.J, Bi, F.K, Guo, C.Y, Yao, H.W, Lin, D.H. | 登録日 | 2018-09-29 | 公開日 | 2019-08-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.397 Å) | 主引用文献 | Crystal structure of the N domain of Lon protease from Mycobacterium avium complex. Protein Sci., 28, 2019
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2KQZ
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2KR0
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7CK9
| Crystal structure of Doxorubicin loaded human ferritin heavy chain | 分子名称: | CHLORIDE ION, Ferritin heavy chain, GLYCEROL, ... | 著者 | Chen, X, Jiang, B, Yan, X, Fan, K. | 登録日 | 2020-07-16 | 公開日 | 2021-05-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.602 Å) | 主引用文献 | A natural drug entry channel in the ferritin nanocage. Nano Today, 35, 2020
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7WCL
| Crystal structure of FGFR1 kinase domain with Pemigatinib | 分子名称: | 11-[2,6-bis(fluoranyl)-3,5-dimethoxy-phenyl]-13-ethyl-4-(morpholin-4-ylmethyl)-5,7,11,13-tetrazatricyclo[7.4.0.0^{2,6}]trideca-1(9),2(6),3,7-tetraen-12-one, Fibroblast growth factor receptor 1, SULFATE ION | 著者 | Chen, X.J, Lin, Q.M, Jiang, L.Y, Qu, L.Z, Chen, Y.H. | 登録日 | 2021-12-20 | 公開日 | 2022-09-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.495 Å) | 主引用文献 | Characterization of the cholangiocarcinoma drug pemigatinib against FGFR gatekeeper mutants. Commun Chem, 5, 2022
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6LBG
| Structure of OR51B2 bound FEM1C | 分子名称: | Protein fem-1 homolog C,Peptide from Olfactory receptor 51B2, SULFATE ION | 著者 | Chen, X, Liao, S, Xu, C. | 登録日 | 2019-11-14 | 公開日 | 2020-10-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
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8U5H
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5XFS
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5YQG
| The structure of 14-3-3 and pNumb peptide | 分子名称: | 14-3-3 protein eta, Peptide from Protein numb homolog | 著者 | Chen, X, Liu, Z, Wen, W. | 登録日 | 2017-11-06 | 公開日 | 2018-02-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural determinants controlling 14-3-3 recruitment to the endocytic adaptor Numb and dissociation of the Numb/alpha-adaptin complex. J. Biol. Chem., 293, 2018
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7DWS
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2OZ4
| Structural Plasticity in IgSF Domain 4 of ICAM-1 Mediates Cell Surface Dimerization | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB FRAGMENT LIGHT CHAIN, ... | 著者 | Chen, X, Kim, T.D, Carman, C.V, Mi, L, Song, G, Springer, T.A. | 登録日 | 2007-02-23 | 公開日 | 2007-10-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural plasticity in Ig superfamily domain 4 of ICAM-1 mediates cell surface dimerization. Proc.Natl.Acad.Sci.Usa, 104, 2007
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1EKA
| NMR AND MOLECULAR MODELING REVEAL THAT DIFFERENT HYDROGEN BONDING PATTERNS ARE POSSIBLE FOR GU PAIRS: ONE HYDROGEN BOND FOR EACH GU PAIR IN R(GGCGUGCC)2 AND TWO FOR EACH GU PAIR IN R(GAGUGCUC)2 | 分子名称: | RNA (5'-R(*GP*AP*GP*UP*GP*CP*UP*C)-3') | 著者 | Chen, X, McDowell, J.A, Kierzek, R, Krugh, T.R, Turner, D.H. | 登録日 | 2000-03-07 | 公開日 | 2000-11-13 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Nuclear magnetic resonance spectroscopy and molecular modeling reveal that different hydrogen bonding patterns are possible for G.U pairs: one hydrogen bond for each G.U pair in r(GGCGUGCC)(2) and two for each G.U pair in r(GAGUGCUC)(2). Biochemistry, 39, 2000
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1EKD
| NMR AND MOLECULAR MODELING REVEAL THAT DIFFERENT HYDROGEN BONDING PATTERNS ARE POSSIBLE FOR GU PAIRS: ONE HYDROGEN BOND FOR EACH GU PAIR IN R(GGCGUGCC)2 AND TWO FOR EACH GU PAIR IN R(GAGUGCUC)2 | 分子名称: | RNA (5'-R(*GP*GP*CP*GP*UP*GP*CP*C)-3') | 著者 | Chen, X, McDowell, J.A, Kierzek, R, Krugh, T.R, Turner, D.H. | 登録日 | 2000-03-07 | 公開日 | 2000-11-13 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Nuclear magnetic resonance spectroscopy and molecular modeling reveal that different hydrogen bonding patterns are possible for G.U pairs: one hydrogen bond for each G.U pair in r(GGCGUGCC)(2) and two for each G.U pair in r(GAGUGCUC)(2). Biochemistry, 39, 2000
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2N3V
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2N3T
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2N3W
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