3R1K
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![BU of 3r1k by Molmil](/molmil-images/mine/3r1k) | Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis H37Rv in complex with CoA and an acetamide moiety | Descriptor: | ACETAMIDE, COENZYME A, Enhanced intracellular survival protein | Authors: | Biswas, T, Chen, W, Garneau-Tsodikova, S, Tsodikov, O.V. | Deposit date: | 2011-03-10 | Release date: | 2011-06-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Unusual regioversatility of acetyltransferase Eis, a cause of drug resistance in XDR-TB. Proc.Natl.Acad.Sci.USA, 108, 2011
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4OD4
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![BU of 4od4 by Molmil](/molmil-images/mine/4od4) | |
5ZRX
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![BU of 5zrx by Molmil](/molmil-images/mine/5zrx) | Crystal Structure of EphA2/SHIP2 Complex | Descriptor: | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2,Ephrin type-A receptor 2 | Authors: | Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M. | Deposit date: | 2018-04-25 | Release date: | 2018-05-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions. Elife, 7, 2018
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5ZRY
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![BU of 5zry by Molmil](/molmil-images/mine/5zry) | Crystal Structure of EphA6/Odin Complex | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Ankyrin repeat and SAM domain-containing protein 1A,Ephrin type-A receptor 6, ... | Authors: | Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M. | Deposit date: | 2018-04-25 | Release date: | 2018-05-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions. Elife, 7, 2018
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6IZK
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![BU of 6izk by Molmil](/molmil-images/mine/6izk) | Structural characterization of mutated NreA protein in nitrate binding site from Staphylococcus aureus | Descriptor: | CHLORIDE ION, IMIDAZOLE, L(+)-TARTARIC ACID, ... | Authors: | Sangare, L, Chen, W, Wang, C, Chen, X, Wu, M, Zhang, X, Zang, J. | Deposit date: | 2018-12-19 | Release date: | 2020-01-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Structural characterization of mutated NreA protein in nitrate binding site from Staphylococcus aureus To Be Published
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8HUD
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![BU of 8hud by Molmil](/molmil-images/mine/8hud) | Cryo-EM structure of the EvCas9-sgRNA-target DNA ternary complex | Descriptor: | CRISPR-associated endonuclease Cas9, Non-target DNA strand, Target DNA strand, ... | Authors: | Tang, N, Wu, Z, Gao, Y, Chen, W, Su, M, Wang, Z, Ji, Q. | Deposit date: | 2022-12-23 | Release date: | 2023-12-27 | Last modified: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.43 Å) | Cite: | Molecular Basis and Genome Editing Applications of a Compact Eubacterium ventriosum CRISPR-Cas9 System. Acs Synth Biol, 13, 2024
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8IDE
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![BU of 8ide by Molmil](/molmil-images/mine/8ide) | Structure of an ancient TsaD-TsaC-SUA5-TcdA modular enzyme (TsaN) | Descriptor: | MANGANESE (II) ION, N(6)-L-threonylcarbamoyladenine synthase | Authors: | Zhang, Z.L, Jin, M.Q, Yu, Z.J, Chen, W, Wang, X.L, Lei, D.S, Zhang, W.H. | Deposit date: | 2023-02-13 | Release date: | 2023-07-26 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Structure-function analysis of an ancient TsaD-TsaC-SUA5-TcdA modular enzyme reveals a prototype of tRNA t6A and ct6A synthetases. Nucleic Acids Res., 51, 2023
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5YCO
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![BU of 5yco by Molmil](/molmil-images/mine/5yco) | Complex structure of PCNA with UHRF2 | Descriptor: | E3 ubiquitin-protein ligase UHRF2, GLYCEROL, Proliferating cell nuclear antigen, ... | Authors: | Wu, M, Chen, W, Hang, T, Wang, C, Zhang, X, Zang, J. | Deposit date: | 2017-09-07 | Release date: | 2017-11-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.199 Å) | Cite: | Structure insights into the molecular mechanism of the interaction between UHRF2 and PCNA. Biochem. Biophys. Res. Commun., 494, 2017
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8JA5
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![BU of 8ja5 by Molmil](/molmil-images/mine/8ja5) | Crystal structure of Nipah Virus attachment (G) glycoprotein in complex with neutralizing antibody 14F8 | Descriptor: | 14F8 antibody heavy chain, 14F8 antibody light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Li, Y.H, Huang, X.Y, Xu, J.J, Chen, W. | Deposit date: | 2023-05-05 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Crystal structure of Nipah Virus attachment (G) glycoprotein in complex with neutralizing antibody 14F8 To Be Published
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8JR5
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8JR3
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![BU of 8jr3 by Molmil](/molmil-images/mine/8jr3) | Crystal structure of Hendra Virus attachment(G) glycoprotein mutant S586N in complex with neutralizing antibody 14F8 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Li, Y.H, Huang, X.Y, Xu, J.J, Chen, W. | Deposit date: | 2023-06-16 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (3.22 Å) | Cite: | Crystal structure of Hendra Virus attachment
(G) glycoprotein mutant S586N in complex with neutralizing antibody 14F8 To Be Published
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7V6F
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![BU of 7v6f by Molmil](/molmil-images/mine/7v6f) | Structure of Candida albicans Fructose-1,6-bisphosphate aldolase complexed with G3P | Descriptor: | Fructose-bisphosphate aldolase, GLYCERALDEHYDE-3-PHOSPHATE, ZINC ION | Authors: | Hongxuan, C, Huang, Y, Han, C, Chen, W, Ren, Y, Wan, J. | Deposit date: | 2021-08-20 | Release date: | 2022-02-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | Structure-Guided Discovery of the Novel Covalent Allosteric Site and Covalent Inhibitors of Fructose-1,6-Bisphosphate Aldolase to Overcome the Azole Resistance of Candidiasis. J.Med.Chem., 65, 2022
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8JOV
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![BU of 8jov by Molmil](/molmil-images/mine/8jov) | Portal-tail complex of phage GP4 | Descriptor: | Portal protein, Putative tail fiber protein, Virion associated protein, ... | Authors: | Liu, H, Chen, W. | Deposit date: | 2023-06-08 | Release date: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Asymmetric Structure of Podophage GP4 Reveals a Novel Architecture of Three Types of Tail Fibers. J.Mol.Biol., 435, 2023
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8JOU
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![BU of 8jou by Molmil](/molmil-images/mine/8jou) | Fiber I and fiber-tail-adaptor of phage GP4 | Descriptor: | Virion-associated phage protein, rope protein of phage GP4 | Authors: | Liu, H, Chen, W. | Deposit date: | 2023-06-08 | Release date: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Asymmetric Structure of Podophage GP4 Reveals a Novel Architecture of Three Types of Tail Fibers. J.Mol.Biol., 435, 2023
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6SAZ
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![BU of 6saz by Molmil](/molmil-images/mine/6saz) | Cleaved human fetuin-b in complex with crayfish astacin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Astacin, ... | Authors: | Gomis-Ruth, F.X, Guevara, T, Cuppari, A, Korschgen, H, Schmitz, C, Kuske, M, Yiallouros, I, Floehr, J, Jahnen-Dechent, W, Stocker, W. | Deposit date: | 2019-07-18 | Release date: | 2019-10-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The C-terminal region of human plasma fetuin-B is dispensable for the raised-elephant-trunk mechanism of inhibition of astacin metallopeptidases. Sci Rep, 9, 2019
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5NJT
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![BU of 5njt by Molmil](/molmil-images/mine/5njt) | Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S dimerization. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Beckert, B, Abdelshahid, M, Schaefer, H, Steinchen, W, Arenz, S, Berninghausen, O, Beckmann, R, Bange, G, Turgay, K, Wilson, D.N. | Deposit date: | 2017-03-29 | Release date: | 2017-06-14 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S dimerization. EMBO J., 36, 2017
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7EN6
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![BU of 7en6 by Molmil](/molmil-images/mine/7en6) | The crystal structure of Escherichia coli MurR in apo form | Descriptor: | HTH-type transcriptional regulator MurR, PHOSPHATE ION | Authors: | Zhang, Y, Chen, W, Ji, Q. | Deposit date: | 2021-04-16 | Release date: | 2022-04-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.276 Å) | Cite: | Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli. Nucleic Acids Res., 50, 2022
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7EN5
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![BU of 7en5 by Molmil](/molmil-images/mine/7en5) | The crystal structure of Escherichia coli MurR in complex with N-acetylglucosamine-6-phosphate | Descriptor: | 2-METHOXYETHANOL, 2-acetamido-2-deoxy-6-O-phosphono-beta-D-glucopyranose, GLYCEROL, ... | Authors: | Zhang, Y, Chen, W, Ji, Q. | Deposit date: | 2021-04-16 | Release date: | 2022-04-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli. Nucleic Acids Res., 50, 2022
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7EN7
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![BU of 7en7 by Molmil](/molmil-images/mine/7en7) | The crystal structure of Escherichia coli MurR in complex with N-acetylmuramic-acid-6-phosphate | Descriptor: | (2R)-2-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-bis(oxidanyl)-6-(phosphonooxymethyl)oxan-4-yl]oxypropanoic acid, HTH-type transcriptional regulator MurR | Authors: | Zhang, Y, Chen, W, Ji, Q. | Deposit date: | 2021-04-16 | Release date: | 2022-04-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli. Nucleic Acids Res., 50, 2022
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8X5L
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![BU of 8x5l by Molmil](/molmil-images/mine/8x5l) | The Crystal Structure of PRKACA from Biortus. | Descriptor: | (2S)-2-(4-chlorophenyl)-2-hydroxy-2-[4-(1H-pyrazol-4-yl)phenyl]ethanaminium, SODIUM ION, cAMP-dependent protein kinase catalytic subunit alpha | Authors: | Wang, F, Cheng, W, Lv, Z, Lin, D, Pan, W. | Deposit date: | 2023-11-17 | Release date: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The Crystal Structure of PRKACA from Biortus. To Be Published
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8ZGD
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![BU of 8zgd by Molmil](/molmil-images/mine/8zgd) | The Crystal Structure of the NLRP1_LRR domain from Biortus. | Descriptor: | GLYCEROL, NACHT, LRR and PYD domains-containing protein 1, ... | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Pan, W. | Deposit date: | 2024-05-09 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The Crystal Structure of the NLRP1_LRR domain from Biortus. To Be Published
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8YVV
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![BU of 8yvv by Molmil](/molmil-images/mine/8yvv) | The Crystal Structure of BTK from Biortus | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Wang, F, Cheng, W, Yuan, Z, Lin, D, Pan, W. | Deposit date: | 2024-03-29 | Release date: | 2024-07-03 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The Crystal Structure of BTK from Biortus. To Be Published
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8WSW
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![BU of 8wsw by Molmil](/molmil-images/mine/8wsw) | The Crystal Structure of LIMK2a from Biortus | Descriptor: | 1,2-ETHANEDIOL, LIM domain kinase 2, ~{N}-[5-[2-[2,6-bis(chloranyl)phenyl]-5-[bis(fluoranyl)methyl]pyrazol-3-yl]-1,3-thiazol-2-yl]-2-methyl-propanamide | Authors: | Wang, F, Cheng, W, Yuan, Z, Lin, D, Pan, W. | Deposit date: | 2023-10-17 | Release date: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Crystal Structure of LIMK2a from Biortus. To Be Published
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8XFY
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![BU of 8xfy by Molmil](/molmil-images/mine/8xfy) | The Crystal Structure of RSK2 from Biortus. | Descriptor: | 2,6-bis(fluoranyl)-4-[4-(4-morpholin-4-ylphenyl)pyridin-3-yl]phenol, Ribosomal protein S6 kinase alpha-3 | Authors: | Wang, F, Cheng, W, Lv, Z, Lin, D, Pan, W. | Deposit date: | 2023-12-14 | Release date: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The Crystal Structure of RSK2 from Biortus. To Be Published
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8ZKD
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![BU of 8zkd by Molmil](/molmil-images/mine/8zkd) | The Crystal Structure of the RON from Biortus. | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, Macrophage-stimulating protein receptor beta chain, ... | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Pan, W. | Deposit date: | 2024-05-16 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The Crystal Structure of the RON from Biortus. To Be Published
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