5Z2T
| Crystal structure of DNA-bound DUX4-HD2 | 分子名称: | 5'-D(*TP*TP*CP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*TP*T)-3', 5'-D(P*AP*AP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*GP*T)-3', Double homeobox protein 4 | 著者 | Dong, X, Zhang, W, Wu, H, Huang, J, Zhang, M, Wang, P, Zhang, H, Chen, Z, Chen, S, Meng, G. | 登録日 | 2018-01-04 | 公開日 | 2018-04-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.623 Å) | 主引用文献 | Structural basis of DUX4/IGH-driven transactivation. Leukemia, 32, 2018
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7DAW
| Crystal structure of Mycobacterium tuberculosis phenylalanyl-tRNA synthetase | 分子名称: | Phenylalanine--tRNA ligase alpha subunit, Phenylalanine--tRNA ligase beta subunit, SULFATE ION | 著者 | Xu, M, Zhang, X, Xu, L, Chen, S. | 登録日 | 2020-10-18 | 公開日 | 2021-01-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | 主引用文献 | Re-discovery of PF-3845 as a new chemical scaffold inhibiting phenylalanyl-tRNA synthetase in Mycobacterium tuberculosis . J.Biol.Chem., 2021
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7DB8
| Crystal structure of Mycobacterium tuberculosis phenylalanyl-tRNA synthetase in complex with compound PF-3845 | 分子名称: | N-pyridin-3-yl-4-[[3-[5-(trifluoromethyl)pyridin-2-yl]oxyphenyl]methyl]piperidine-1-carboxamide, Phenylalanine--tRNA ligase alpha subunit, Phenylalanine--tRNA ligase beta subunit, ... | 著者 | Xu, M, Zhang, X, Xu, L, Chen, S. | 登録日 | 2020-10-19 | 公開日 | 2021-01-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Re-discovery of PF-3845 as a new chemical scaffold inhibiting phenylalanyl-tRNA synthetase in Mycobacterium tuberculosis . J.Biol.Chem., 2021
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6IV3
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6IV0
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6IVW
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6IV4
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6IV2
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6J2B
| CTX-M-64 beta-lactamase S130T sulbactam complex | 分子名称: | Beta-lactamase, GLYCEROL, TRANS-ENAMINE INTERMEDIATE OF SULBACTAM | 著者 | Cheng, Q, Chen, S. | 登録日 | 2018-12-31 | 公開日 | 2019-10-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Structural Insight into the Mechanism of Inhibitor Resistance in CTX-M-199, a CTX-M-64 Variant Carrying the S130T Substitution. Acs Infect Dis., 6, 2020
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6J2O
| Crystal structure of CTX-M-64 clavulanic acid complex | 分子名称: | (2E)-3-[(4-hydroxy-2-oxobutyl)amino]prop-2-enal, Beta-lactamase | 著者 | Cheng, Q, Chen, S. | 登録日 | 2019-01-02 | 公開日 | 2019-10-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Insight into the Mechanism of Inhibitor Resistance in CTX-M-199, a CTX-M-64 Variant Carrying the S130T Substitution. Acs Infect Dis., 6, 2020
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6J25
| CTX-M-64 beta-lactamase mutant-S130T | 分子名称: | Beta-lactamase | 著者 | Cheng, Q, Chen, S. | 登録日 | 2018-12-30 | 公開日 | 2019-10-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structural Insight into the Mechanism of Inhibitor Resistance in CTX-M-199, a CTX-M-64 Variant Carrying the S130T Substitution. Acs Infect Dis., 6, 2020
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7X4E
| Structure of 10635-DndE | 分子名称: | DNA sulfur modification protein DndE, GLYCEROL | 著者 | Haiyan, G, Wei, H, Chen, S, Wang, L, Wu, G. | 登録日 | 2022-03-02 | 公開日 | 2022-04-20 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Structural and Functional Analysis of DndE Involved in DNA Phosphorothioation in the Haloalkaliphilic Archaea Natronorubrum bangense JCM10635. Mbio, 13, 2022
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6JLF
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6JV4
| Crystal structure of metallo-beta-lactamase VMB-1 | 分子名称: | CITRIC ACID, VMB-1, ZINC ION | 著者 | Cheng, Q, Chen, S. | 登録日 | 2019-04-15 | 公開日 | 2019-11-27 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Genetic and Biochemical Characterization of VMB-1, a Novel Metallo-beta-Lactamase Encoded by a Conjugative, Broad-Host Range IncC Plasmid from Vibrio spp. Adv Biosyst, 4, 2020
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6ITY
| CTX-M-64 sulbactam complex | 分子名称: | ACRYLIC ACID, Beta-lactamase, TRANS-ENAMINE INTERMEDIATE OF SULBACTAM | 著者 | Cheng, Q, Chen, S. | 登録日 | 2018-11-26 | 公開日 | 2019-10-30 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Structural Insight into the Mechanism of Inhibitor Resistance in CTX-M-199, a CTX-M-64 Variant Carrying the S130T Substitution. Acs Infect Dis., 6, 2020
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6IV1
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6J2K
| CTX-M-64 beta-lactamase S130T clavulanic acid complex | 分子名称: | (2E)-3-[(4-hydroxy-2-oxobutyl)amino]prop-2-enal, Beta-lactamase | 著者 | Cheng, Q, Chen, S. | 登録日 | 2019-01-01 | 公開日 | 2019-10-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Structural Insight into the Mechanism of Inhibitor Resistance in CTX-M-199, a CTX-M-64 Variant Carrying the S130T Substitution. Acs Infect Dis., 6, 2020
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7DRI
| Structure of SspE_CTD_41658 | 分子名称: | DUF1524 domain | 著者 | Haiyan, G, Jinchuan, Z, Chen, S, Wang, L, Wu, G. | 登録日 | 2020-12-28 | 公開日 | 2022-06-29 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE. Nat Commun, 13, 2022
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7DRS
| Structure of SspE_40224 | 分子名称: | SspE protein | 著者 | Haiyan, G, Jinchuan, Z, Chen, S, Wang, L, Wu, G. | 登録日 | 2020-12-29 | 公開日 | 2022-06-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | 主引用文献 | Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE. Nat Commun, 13, 2022
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7DRR
| Structure of SspE-R100A protein | 分子名称: | SspE protein | 著者 | Haiyan, G, Jinchuan, Z, Chen, S, Wang, L, Wu, G. | 登録日 | 2020-12-29 | 公開日 | 2022-06-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.48 Å) | 主引用文献 | Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE. Nat Commun, 13, 2022
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7DK2
| Crystal structure of SARS-CoV-2 Spike RBD in complex with MW07 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MW07 heavy chain, MW07 light chain, ... | 著者 | Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M, Chen, S. | 登録日 | 2020-11-22 | 公開日 | 2021-12-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Architectural versatility of spike neutralization by a SARS-CoV-2 antibody To Be Published
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7EL8
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7ELT
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7ENT
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7ENS
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