6IV2

Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae with a mutation Y211A

Summary for 6IV2

Entry DOI	10.2210/pdb6iv2/pdb
Related	4wd8
Descriptor	Bestrophin homolog, ZINC ION (3 entities in total)
Functional Keywords	bestrophin-1, homolog, mutation, klebsiella pneumoniae, membrane protein
Biological source	Klebsiella pneumoniae IS53
Total number of polymer chains	5
Total formula weight	169045.26
Authors	Kittredge, A.,Chen, S.,Yang, T. (deposition date: 2018-12-02, release date: 2019-11-13, Last modification date: 2022-06-08)
Primary citation	Ji, C.,Kittredge, A.,Hopiavuori, A.,Ward, N.,Chen, S.,Fukuda, Y.,Zhang, Y.,Yang, T. Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations. Commun Biol, 2:240-240, 2019 Cited by PubMed: 31263784 DOI: 10.1038/s42003-019-0433-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.62 Å)

Structure validation