2MX8
 
 | | NMR structure of N-terminal domain from A. ventricosus minor ampullate spidroin (MiSp) at pH 7.2 | | 分子名称: | Minor ampullate spidroin | | 著者 | Otikovs, M, Jaudzems, K, Chen, G, Nordling, K, Rising, A, Johansson, J. | | 登録日 | 2014-12-17 | | 公開日 | 2015-08-19 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Diversified Structural Basis of a Conserved Molecular Mechanism for pH-Dependent Dimerization in Spider Silk N-Terminal Domains.
Chembiochem, 16, 2015
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6PKC
 | | Inhibition of Human Menin by VTP-50469 | | 分子名称: | 5-fluoro-2-({4-[7-({trans-4-[(methylsulfonyl)amino]cyclohexyl}methyl)-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl}oxy)-N,N-di(propan-2-yl)benzamide, Menin,Menin | | 著者 | McKeever, B.M, Chen, G, Van Orton, R. | | 登録日 | 2019-06-29 | | 公開日 | 2019-12-18 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia.
Cancer Cell, 36, 2019
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7CUK
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7VFX
 | | The structure of Formyl Peptide Receptor 1 in complex with Gi and peptide agonist fMIFL | | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Wang, X.K, Chen, G, Liao, Q.W, Du, Y, Hu, H.L, Ye, D.Q. | | 登録日 | 2021-09-14 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis for recognition of N-formyl peptides as pathogen-associated molecular patterns.
Nat Commun, 13, 2022
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7E7N
 | | Crystal structure of RSL mutant-R17A/R108A/R199A in complex with R3F | | 分子名称: | 2-[2-[2-[4-[[(2R,3S,4R,5S,6S)-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxymethyl]-1,2,3-triazol-1-yl]ethoxy]ethoxy]ethyl 2-[3,6-bis(diethylamino)-9H-xanthen-9-yl]benzoate, Fucose-binding lectin protein,Fucose-binding lectin protein,Fucose-binding lectin protein, GLYCEROL | | 著者 | Li, L, Chen, G.S. | | 登録日 | 2021-02-26 | | 公開日 | 2021-04-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal structure of RSL mutant in complex with suger Ligand
To Be Published
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7E7W
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7E7V
 | | Crystal structure of RSL mutant in complex with sugar Ligand | | 分子名称: | 2-[2-[2-[4-[[(2R,3S,4R,5S,6S)-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxymethyl]-1,2,3-triazol-1-yl]ethoxy]ethoxy]ethyl 2-[3,6-bis(diethylamino)-9H-xanthen-9-yl]benzoate, Fucose-binding lectin protein,Fucose-binding lectin protein,Fucose-binding lectin protein, GLYCEROL | | 著者 | Li, L, Chen, G.S. | | 登録日 | 2021-02-28 | | 公開日 | 2021-04-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Crystal structure of RSL mutant in complex with Ligand
To Be Published
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7E7T
 | | Crystal structure of RSL mutant in complex with sugar Ligand | | 分子名称: | 2-[2-[4-[[(2R,3S,4R,5S,6S)-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxymethyl]-1,2,3-triazol-1-yl]ethoxy]ethyl 2-[3,6-bis(diethylamino)-9H-xanthen-9-yl]benzoate, Fucose-binding lectin protein,Fucose-binding lectin protein,Fucose-binding lectin protein | | 著者 | Li, L, Chen, G.S. | | 登録日 | 2021-02-27 | | 公開日 | 2021-04-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Crystal structure of RSL mutant-R17A/R108A/R199A in complex with R2F
To Be Published
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7E7U
 | | Crystal structure of RSL mutant in complex with sugar Ligand | | 分子名称: | 2-[2-[4-[[(2R,3S,4R,5S,6S)-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxymethyl]-1,2,3-triazol-1-yl]ethoxy]ethyl 2-[3,6-bis(diethylamino)-9H-xanthen-9-yl]benzoate, Fucose-binding lectin protein,Fucose-binding lectin protein,Fucose-binding lectin protein, GLYCEROL | | 著者 | Li, L, Chen, G.S. | | 登録日 | 2021-02-27 | | 公開日 | 2021-04-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of RSL mutant in complex with Ligand
To Be Published
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7E7R
 | | Crystal structure of RSL mutant in complex with Ligand | | 分子名称: | 2-[2-[4-[[(2R,3S,4R,5S,6S)-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxymethyl]-1,2,3-triazol-1-yl]ethoxy]ethyl 2-[3,6-bis(diethylamino)-9H-xanthen-9-yl]benzoate, Fucose-binding lectin protein,Fucose-binding lectin protein,Fucose-binding lectin protein | | 著者 | Li, L, Chen, G.S. | | 登録日 | 2021-02-27 | | 公開日 | 2021-04-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Crystal structure of RSL mutant-R17A/R108A/R199A in complex with R3F
To Be Published
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6L5Z
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6LK0
 | | Crystal structure of human wild type TRIP13 | | 分子名称: | Pachytene checkpoint protein 2 homolog | | 著者 | Wang, Y, Huang, J, Li, B, Xue, H, Tricot, G, Hu, L, Xu, Z, Sun, X, Chang, S, Gao, L, Tao, Y, Xu, H, Xie, Y, Xiao, W, Yu, D, Kong, Y, Chen, G, Sun, X, Lian, F, Zhang, N, Wu, X, Mao, Z, Zhan, F, Zhu, W, Shi, J. | | 登録日 | 2019-12-17 | | 公開日 | 2020-01-22 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression.
Cancer Res., 80, 2020
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7EJX
 | | Structure of the GPR88-Gi1 signaling complex bound to a synthetic ligand | | 分子名称: | (1R,2R)-N-[(2S,3S)-2-azanyl-3-methyl-pentyl]-N-[4-(4-propylphenyl)phenyl]-2-pyridin-2-yl-cyclopropane-1-carboxamide, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Xu, J, Chen, G, Liu, Z, Du, Y. | | 登録日 | 2021-04-02 | | 公開日 | 2022-04-13 | | 最終更新日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Activation and allosteric regulation of the orphan GPR88-Gi1 signaling complex.
Nat Commun, 13, 2022
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6KVB
 | | Structure of an intra-locked G-quadruplex | | 分子名称: | DNA (28-mer) | | 著者 | Maity, A, Winnerdy, F.R, Chang, W.D, Chen, G, Phan, A.T. | | 登録日 | 2019-09-03 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Intra-locked G-quadruplex structures formed by irregular DNA G-rich motifs.
Nucleic Acids Res., 48, 2020
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5ZAC
 | | Crystal structure of ConA-R2M | | 分子名称: | 2H-1,2,3-TRIAZOL-4-YLMETHANOL, CALCIUM ION, Concanavalin-A, ... | | 著者 | Gan, J.H, Chen, G.S, Hu, R.T. | | 登録日 | 2018-02-07 | | 公開日 | 2018-05-30 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Competition between Supramolecular Interaction and Protein-Protein Interaction in Protein Crystallization:Effects of Crystallization Method and Small Molecular Bridge
Ind Eng Chem Res, 57, 2018
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5Z5L
 | | Crystal structure of ConA-R5M | | 分子名称: | (1-methyl-1H-1,2,3-triazol-4-yl)methyl alpha-D-mannopyranoside, CALCIUM ION, Concanavalin-A, ... | | 著者 | Hu, R.T, Gan, J.H, Chen, G.S. | | 登録日 | 2018-01-18 | | 公開日 | 2019-04-10 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of ConA-R5M
To Be Published
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7VF1
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7X2E
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7Y89
 | | Structure of the GPR17-Gi complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Ye, F, Chen, G. | | 登録日 | 2022-06-23 | | 公開日 | 2022-10-12 | | 最終更新日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | Cryo-EM structure of G-protein-coupled receptor GPR17 in complex with inhibitory G protein.
MedComm (2020), 3, 2022
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7YFV
 | | Structure of Rpgrip1l CC1 | | 分子名称: | Protein fantom | | 著者 | He, R, Chen, G, Li, Z, Li, J. | | 登録日 | 2022-07-09 | | 公開日 | 2023-05-17 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of the N-terminal coiled-coil domains of the ciliary protein Rpgrip1l.
Iscience, 26, 2023
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7YFU
 | | Structure of Rpgrip1l CC2 | | 分子名称: | Protein fantom | | 著者 | He, R, Chen, G, Li, Z, Li, J. | | 登録日 | 2022-07-09 | | 公開日 | 2023-05-17 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of the N-terminal coiled-coil domains of the ciliary protein Rpgrip1l.
Iscience, 26, 2023
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7WZ4
 | | Structure of an orphan GPCR-G protein signaling complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Xu, J, Chen, G, Liu, Z, Du, Y. | | 登録日 | 2022-02-17 | | 公開日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Activation and allosteric regulation of the orphan GPR88-Gi1 signaling complex.
Nat Commun, 13, 2022
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4GJH
 | | Crystal Structure of the TRAF domain of TRAF5 | | 分子名称: | TNF receptor-associated factor 5 | | 著者 | Zhang, P, Reichardt, A, Liang, H, Wang, Y, Cheng, D, Aliyari, R, Cheng, G, Liu, Y. | | 登録日 | 2012-08-09 | | 公開日 | 2012-11-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.805 Å) | | 主引用文献 | Single Amino Acid Substitutions Confer the Antiviral Activity of the TRAF3 Adaptor Protein onto TRAF5
Sci.Signal., 5, 2012
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5W3K
 | | Crystal structure of Staphylococcus aureus ketol-acid reductoisomerase in complex NADPH, Mg2+ and CPD | | 分子名称: | Ketol-acid reductoisomerase (NADP(+)), MAGNESIUM ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Patel, K.M, Teran, D, Zheng, S, Kandale, A, Schembri, M, McGeary, R.P, Schenk, G, Guddat, L.W. | | 登録日 | 2017-06-08 | | 公開日 | 2017-10-25 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.589 Å) | | 主引用文献 | Crystal Structures of Staphylococcus aureus Ketol-Acid Reductoisomerase in Complex with Two Transition State Analogues that Have Biocidal Activity.
Chemistry, 23, 2017
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6DN4
 | | Cronobacter sakazakii (Enterobacter sakazakii) Metallo-beta-lactamse HARLDQ motif | | 分子名称: | Beta-lactamase | | 著者 | Monteiro Pedroso, M, Waite, D, Natasa, M, McGeary, R, Guddat, L, Hugenholtz, P, Schenk, G. | | 登録日 | 2018-06-06 | | 公開日 | 2019-06-12 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Broad spectrum antibiotic-degrading metallo-beta-lactamases are phylogenetically diverse
Protein Cell, 2020
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