7QQD
 
 | | Nuclear factor one X - NFIX in P21 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NFI binding site (forward), NFI binding site (reverse), ... | | 著者 | Lapi, M, Chaves-Sanjuan, A, Gourlay, L.J, Tiberi, M, Polentarutti, M, Demitri, N, Bais, G, Nardini, M. | | 登録日 | 2022-01-07 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Nuclear factor one X - NFIX in P41212
To Be Published
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5FYX
 | | Crystal structure of Drosophila NCS-1 bound to penothiazine FD16 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, FREQUENIN 2, ... | | 著者 | Martinez-Gonzalez, L, Chaves-Sanjuan, A, Infantes, L, Sanchez-Barrena, M.J. | | 登録日 | 2016-03-10 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Interference of the complex between NCS-1 and Ric8a with phenothiazines regulates synaptic function and is an approach for fragile X syndrome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5NWJ
 | | 14-3-3c in complex with CPP7 | | 分子名称: | 14-3-3-like protein C, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Saponaro, A, Porro, A, Chaves-Sanjuan, A, Nardini, M, Thiel, G, Moroni, A. | | 登録日 | 2017-05-06 | | 公開日 | 2017-11-22 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins.
Plant Cell, 29, 2017
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5NWI
 | | 14-3-3c in complex with CPP | | 分子名称: | 14-3-3 c-1 protein, ACETATE ION, Potassium channel KAT1 | | 著者 | Saponaro, A, Porro, A, Chaves-Sanjuan, A, Nardini, M, Thiel, G, Moroni, A. | | 登録日 | 2017-05-06 | | 公開日 | 2017-11-22 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins.
Plant Cell, 29, 2017
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5NWK
 | | 14-3-3c in complex with CPP and fusicoccin | | 分子名称: | 14-3-3 c-1 protein, FUSICOCCIN, PHOSPHOSERINE, ... | | 著者 | Saponaro, A, Porro, A, Chaves-Sanjuan, A, Nardini, M, Thiel, G, Moroni, A. | | 登録日 | 2017-05-06 | | 公開日 | 2017-11-22 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins.
Plant Cell, 29, 2017
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5G49
 | | Crystal structure of the Arabodopsis thaliana histone-fold dimer L1L NF-YC3 | | 分子名称: | ACETATE ION, CALCIUM ION, NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT B-6, ... | | 著者 | Gnesutta, N, Saad, D, Chaves-Sanjuan, A, Mantovani, R, Nardini, M. | | 登録日 | 2016-05-06 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure of the Arabidopsis thaliana L1L/NF-YC3 Histone-fold Dimer Reveals Specificities of the LEC1 Family of NF-Y Subunits in Plants.
Mol Plant, 10, 2017
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8A11
 | | Cryo-EM structure of the Human SHMT1-RNA complex | | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, Serine hydroxymethyltransferase, cytosolic | | 著者 | Spizzichino, S, Marabelli, C, Bharadwaj, A, Jakobi, A.J, Chaves-Sanjuan, A, Giardina, G, Bolognesi, M, Cutruzzola, F. | | 登録日 | 2022-05-30 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | | 主引用文献 | Structure-based mechanism of riboregulation of the metabolic enzyme SHMT1.
Mol.Cell, 2024
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7ZH7
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9FAA
 | | Cryo-EM structure of cardiac collagen-associated amyloid AL59 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Monoclonal immunoglobulin light chains (LC) | | 著者 | Schulte, T, Speranzini, V, Chaves-Sanjuan, A, Milazzo, M, Ricagno, S. | | 登録日 | 2024-05-10 | | 公開日 | 2024-07-17 | | 最終更新日 | 2024-08-14 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis.
Nat Commun, 15, 2024
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7ZIR
 | | Cryo-EM structure of hnRNPDL amyloid fibrils | | 分子名称: | Heterogeneous nuclear ribonucleoprotein D-like | | 著者 | Garcia-Pardo, J, Chaves-Sanjuan, A, Bartolome-Nafria, A, Gil-Garcia, M, Visentin, C, Bolognesi, M, Ricagno, S, Ventura, S. | | 登録日 | 2022-04-08 | | 公開日 | 2022-12-28 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Cryo-EM structure of hnRNPDL-2 fibrils, a functional amyloid associated with limb-girdle muscular dystrophy D3.
Nat Commun, 14, 2023
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9FGU
 | | SARS-CoV-2 (B.1.1.529/Omicron variant) Spike protein in complex with the single chain fragment scFv76-77 (focused refinement) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, scFv76-77 single chain fragment | | 著者 | Berlinguer, M, Chaves-Sanjuan, A, Milazzo, F.M, Minenkova, O, De Santis, R, Bolognesi, M. | | 登録日 | 2024-05-25 | | 公開日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structure of scFv76-77 in complex with SARS-CoV-2 Omicron Spike protein
To Be Published
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9FGT
 | | SARS-CoV-2 (B.1.1.529/Omicron variant) Spike protein in complex with the single chain fragment scFv76 (focused refinement) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Single chain fragment scFv76, Spike glycoprotein,Fibritin | | 著者 | Berlinguer, M, Chaves-Sanjuan, A, Milazzo, F.M, Minenkova, O, De Santis, R, Bolognesi, M. | | 登録日 | 2024-05-25 | | 公開日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure of scFv76 in complex with SARS-CoV-2 Omicron Spike protein
To Be Published
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9FGS
 | | SARS-CoV-2 (wuhan variant) Spike protein in complex with the single chain fragment scFv41N (focused refinement) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Single Chain fragment scFv41N, Spike glycoprotein,Fibritin | | 著者 | Berlinguer, M, Chaves-Sanjuan, A, Milazzo, F.M, Minenkova, O, De Santis, R, Bolognesi, M. | | 登録日 | 2024-05-25 | | 公開日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structure of scFv41N in complex with SARS-CoV-2 Spike protein
To Be Published
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9FGR
 | | SARS-CoV-2 (wuhan variant) Spike protein in complex with the single chain fragment scFv76-77 (focused refinement) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, scFv76-77 single chain fragment | | 著者 | Berlinguer, M, Chaves-Sanjuan, A, Milazzo, F.M, Minenkova, O, De Santis, R, Bolognesi, M. | | 登録日 | 2024-05-25 | | 公開日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structure of scFv76-77 in complex with SARS-CoV-2 Spike protein
To Be Published
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9FAC
 | | Additional cryo-EM structure of cardiac amyloid AL59 - mixed polymorph | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Monoclonal immunoglobulin light chains (LC) | | 著者 | Schulte, T, Speranzini, V, Chaves-Sanjuan, A, Milazzo, M, Ricagno, S. | | 登録日 | 2024-05-10 | | 公開日 | 2024-08-14 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis.
To be published
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9FAB
 | | Additional cryo-EM structure of cardiac amyloid AL59 - bent polymorph | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Monoclonal immunoglobulin light chains (LC) | | 著者 | Schulte, T, Speranzini, V, Chaves-Sanjuan, A, Milazzo, M, Ricagno, S. | | 登録日 | 2024-05-10 | | 公開日 | 2024-08-14 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Additional cryo-EM structure of cardiac amyloid AL59 - bent polymorph
To be published
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4BY5
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4BY4
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4D28
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6RJD
 | | Cryo-EM structure of St1Cas9-sgRNA-tDNA59-ntPAM complex. | | 分子名称: | Streptococcus Thermophilus 1 Cas9, ntPAM, sgRNA (78-MER), ... | | 著者 | Goulet, A, Chaves-Sanjuan, A, Cambillau, C. | | 登録日 | 2019-04-26 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6.
Mol.Cell, 76, 2019
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6RJ9
 | | Cryo-EM structure of St1Cas9-sgRNA-tDNA20-AcrIIA6 monomeric assembly. | | 分子名称: | AcrIIA6, CRISPR-associated endonuclease Cas9 1, sgRNA, ... | | 著者 | Goulet, A, Chaves-Sanjuan, A, Cambillau, C. | | 登録日 | 2019-04-26 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6.
Mol.Cell, 76, 2019
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6RJG
 | | Cryo-EM structure of St1Cas9-sgRNA-AcrIIA6-tDNA59-ntPAM complex. | | 分子名称: | AcrIIA6, Cas 9, ntPAM, ... | | 著者 | Goulet, A, Chaves-Sanjuan, A, Cambillau, C. | | 登録日 | 2019-04-26 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6.
Mol.Cell, 76, 2019
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6RJA
 | | Cryo-EM structure of St1Cas9-sgRNA-tDNA20-AcrIIA6 dimeric assembly. | | 分子名称: | AcrIIA6, CRISPR-associated endonuclease Cas9 1, RNA (78-MER), ... | | 著者 | Goulet, A, Cambillau, C, Chaves-Sanjuan, A. | | 登録日 | 2019-04-26 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6.
Mol.Cell, 76, 2019
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