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PDB: 281 件

4KDP
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TcaR-ssDNA complex crystal structure reveals the novel ssDNA binding mechanism of the MarR family proteins
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (5'-D(*CP*GP*CP*AP*GP*CP*GP*CP*GP*CP*AP*GP*CP*CP*CP*TP*A)-3'), ...
著者Chang, Y.M, Chen, C.K.-M, Wang, A.H.-J.
登録日2013-04-25
公開日2014-03-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献TcaR-ssDNA complex crystal structure reveals new DNA binding mechanism of the MarR family proteins.
Nucleic Acids Res., 42, 2014
6AG5
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BU of 6ag5 by Molmil
Crystal structure of Ard1 N-terminal acetyltransferase E88H/H127E mutant from Sulfolobus solfataricus
分子名称: ACETYL COENZYME *A, CALCIUM ION, N-alpha-acetyltransferase
著者Chang, Y.Y, Hsu, C.H.
登録日2018-08-09
公開日2019-08-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Adaptation of thermophilic acetyltransferase to a water-mediated catalytic mechanism.
Chem.Commun.(Camb.), 56, 2020
7UDL
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BU of 7udl by Molmil
Crystal structure of designed helical repeat protein RPB_PLP1_R6 bound to PLPx6 peptide
分子名称: 1,2-ETHANEDIOL, 6xPLP Peptide, Designed helical repeat protein (DHR) RPB_PLP1_R6
著者Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C.
登録日2022-03-20
公開日2023-03-22
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
3QXY
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BU of 3qxy by Molmil
Human SETD6 in complex with RelA Lys310
分子名称: 1,2-ETHANEDIOL, N-lysine methyltransferase SETD6, S-ADENOSYLMETHIONINE, ...
著者Chang, Y, Levy, D, Horton, J.R, Peng, J, Zhang, X, Gozani, O, Cheng, X.
登録日2011-03-02
公開日2011-05-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling.
Nucleic Acids Res., 39, 2011
4GN1
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BU of 4gn1 by Molmil
Crystal Structure of the RA and PH domains of Lamellipodin
分子名称: MALONATE ION, Ras-associated and pleckstrin homology domains-containing protein 1
著者Chang, Y.C.E, Wu, J.
登録日2012-08-16
公開日2012-11-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of Lamellipodin implicates diverse functions in actin polymerization and Ras signaling.
Protein Cell, 4, 2013
3RC0
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BU of 3rc0 by Molmil
Human SETD6 in complex with RelA Lys310 peptide
分子名称: 1,2-ETHANEDIOL, N-lysine methyltransferase SETD6, S-ADENOSYLMETHIONINE, ...
著者Chang, Y, Levy, D, Horton, J.R, Peng, J, Zhang, X, Gozani, O, Cheng, X.
登録日2011-03-30
公開日2011-05-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling.
Nucleic Acids Res., 39, 2011
4GMV
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BU of 4gmv by Molmil
Crystal Structure of the coiled-coil, RA and PH domains of Lamellipodin
分子名称: Ras-associated and pleckstrin homology domains-containing protein 1
著者Chang, Y.C.E, Wu, J.
登録日2012-08-16
公開日2012-11-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.403 Å)
主引用文献Crystal structure of Lamellipodin implicates diverse functions in actin polymerization and Ras signaling.
Protein Cell, 4, 2013
6E31
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BU of 6e31 by Molmil
Crystal structure of RIAM in an autoinhibited configuration.
分子名称: Rap1-interacting adapter molecule
著者Chang, Y.C, Su, W, Zhang, H, Huang, Q, Philips, M.R, Wu, J.
登録日2018-07-12
公開日2019-02-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis for autoinhibition of RIAM regulated by FAK in integrin activation.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
3SWC
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BU of 3swc by Molmil
GLP (G9a-like protein) SET domain in complex with Dnmt3aK44me2 peptide
分子名称: DNA (cytosine-5)-methyltransferase 3A, Histone-lysine N-methyltransferase EHMT1, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Chang, Y, Horton, J.R, Zhang, X, Cheng, X.
登録日2011-07-13
公開日2011-11-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.332 Å)
主引用文献MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
Nat Commun, 2, 2011
4GDF
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BU of 4gdf by Molmil
A Crystal Structure of SV40 Large T Antigen
分子名称: DNA (32-MER), Large T antigen, ZINC ION
著者Chang, Y.P, Xu, M, Chen, X.S.
登録日2012-07-31
公開日2013-04-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanism of Origin DNA Recognition and Assembly of an Initiator-Helicase Complex by SV40 Large Tumor Antigen.
Cell Rep, 3, 2013
3SW9
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BU of 3sw9 by Molmil
GLP (G9a-like protein) SET domain in complex with Dnmt3aK44me0 peptide
分子名称: DNA (cytosine-5)-methyltransferase 3A, Histone-lysine N-methyltransferase EHMT1, SINEFUNGIN, ...
著者Chang, Y, Horton, J.R, Zhang, X, Cheng, X.
登録日2011-07-13
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
Nat Commun, 2, 2011
3FPD
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BU of 3fpd by Molmil
G9a-like protein lysine methyltransferase inhibition by BIX-01294
分子名称: Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine, ...
著者Chang, Y, Zhang, X, Horton, J.R, Cheng, X.
登録日2009-01-05
公開日2009-02-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294.
Nat.Struct.Mol.Biol., 16, 2009
3SVM
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BU of 3svm by Molmil
Human MPP8 - human DNMT3AK47me2 peptide
分子名称: DNA (cytosine-5)-methyltransferase 3A, M-phase phosphoprotein 8
著者Chang, Y, Horton, J.R, Zhang, X, Cheng, X.
登録日2011-07-12
公開日2011-11-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
Nat Commun, 2, 2011
5ZLC
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BU of 5zlc by Molmil
Binary complex of human DNA Polymerase Mu with MndGTP
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, ...
著者Chang, Y.K, Wu, W.J, Tsai, M.D.
登録日2018-03-27
公開日2019-05-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
4EM2
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BU of 4em2 by Molmil
seleno-methionine staphylococcus aureus MarR in complex with salicylate
分子名称: 2-HYDROXYBENZOIC ACID, SULFATE ION, Uncharacterized HTH-type transcriptional regulator SAR2349
著者Chang, Y.M, Ko, T.-P, Chen, C.K.-M, Wang, A.H.-J.
登録日2012-04-11
公開日2013-04-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Staphylococcus aureus MarR complexes
To be Published
6AK5
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BU of 6ak5 by Molmil
Binary Complex of Human DNA Polymerase Mu with MnGTP
分子名称: DNA-directed DNA/RNA polymerase mu, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
著者Chang, Y.K, Wu, W.J, Tsai, M.D.
登録日2018-08-30
公開日2019-05-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6AEC
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BU of 6aec by Molmil
Binary complex of human DNA Polymerase Mu with MnATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, ...
著者Chang, Y.K, Wu, W.J, Tsai, M.D.
登録日2018-08-04
公開日2019-05-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6AK9
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BU of 6ak9 by Molmil
Pre-catalytic Ternary Complex of Human DNA Polymerase Mu with Templating Cytosine and Incoming Ca-8oxodGTP
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
著者Chang, Y.K, Wu, W.J, Tsai, M.D.
登録日2018-08-30
公開日2019-05-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6AK8
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BU of 6ak8 by Molmil
Pre-catalytic Ternary Complex of Human DNA Polymerase Mu with Templating Adenine and Incoming Ca-8oxodGTP
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
著者Chang, Y.K, Wu, W.J, Tsai, M.D.
登録日2018-08-30
公開日2019-05-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
4EM1
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BU of 4em1 by Molmil
staphylococcus aureus MarR native
分子名称: Uncharacterized HTH-type transcriptional regulator SAR2349
著者Chang, Y.M, Chen, C.K.-M, Wang, A.H.-J.
登録日2012-04-11
公開日2013-04-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Staphylococcus aureus MarR native
To be Published
6AKH
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BU of 6akh by Molmil
Pre-catalytic Ternary Complex of Human DNA Polymerase Mu with Templating Adenine and Incoming Mn-dUMPNPP
分子名称: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Chang, Y.K, Wu, W.J, Tsai, M.D.
登録日2018-08-31
公開日2019-05-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6AEH
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BU of 6aeh by Molmil
Binary complex of human DNA Polymerase Mu with MnUTP
分子名称: DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, SULFATE ION, ...
著者Chang, Y.K, Wu, W.J, Tsai, M.D.
登録日2018-08-04
公開日2019-05-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6AK6
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BU of 6ak6 by Molmil
Binary Complex of Human DNA Polymerase Mu with MnCTP
分子名称: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, ...
著者Chang, Y.K, Wu, W.J, Tsai, M.D.
登録日2018-08-30
公開日2019-05-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
5C88
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BU of 5c88 by Molmil
Crystal structure of Ard1 N-terminal acetyltransferase from Sulfolobus solfataricus in monoclinic form
分子名称: COENZYME A, Uncharacterized N-acetyltransferase SSO0209
著者Chang, Y.Y, Hsu, C.H.
登録日2015-06-25
公開日2016-01-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Multiple Conformations of the Loop Region Confers Heat-Resistance on SsArd1, a Thermophilic NatA.
Chembiochem, 17, 2016
4EM0
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BU of 4em0 by Molmil
staphylococcus aureus MarR in complex with salicylate and kanamycin
分子名称: 2-HYDROXYBENZOIC ACID, KANAMYCIN A, Uncharacterized HTH-type transcriptional regulator SAR2349
著者Chang, Y.M, Chen, C.K.-M, Wang, A.H.-J.
登録日2012-04-11
公開日2013-04-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Staphylococcus aureus MarR complexes
To be Published

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件を2024-10-30に公開中

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