6N8D
 
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3IAA
 | | Crystal Structure of CalG2, Calicheamicin Glycosyltransferase, TDP bound form | | 分子名称: | CalG2, THYMIDINE-5'-DIPHOSPHATE | | 著者 | Chang, A, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N. | | 登録日 | 2009-07-13 | | 公開日 | 2010-06-02 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.505 Å) | | 主引用文献 | Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3IA7
 | | Crystal Structure of CalG4, the Calicheamicin Glycosyltransferase | | 分子名称: | CALCIUM ION, CHLORIDE ION, CalG4 | | 著者 | Chang, A, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N. | | 登録日 | 2009-07-13 | | 公開日 | 2010-06-02 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3OTG
 | | Crystal Structure of CalG1, Calicheamicin Glycostyltransferase, TDP bound form | | 分子名称: | CHLORIDE ION, CalG1, THYMIDINE-5'-DIPHOSPHATE | | 著者 | Chang, A, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2010-09-11 | | 公開日 | 2010-12-15 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3OTI
 | | Crystal Structure of CalG3, Calicheamicin Glycostyltransferase, TDP and calicheamicin T0 bound form | | 分子名称: | CHLORIDE ION, CalG3, Calicheamicin T0, ... | | 著者 | Chang, A, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2010-09-11 | | 公開日 | 2010-12-15 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.597 Å) | | 主引用文献 | Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3OTH
 | | Crystal Structure of CalG1, Calicheamicin Glycostyltransferase, TDP and calicheamicin alpha3I bound form | | 分子名称: | CalG1, Calicheamicin alpha3I, THYMIDINE-5'-DIPHOSPHATE | | 著者 | Chang, A, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2010-09-11 | | 公開日 | 2010-12-15 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | | 主引用文献 | Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3PKP
 | | Q83S Variant of S. Enterica RmlA with dATP | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Glucose-1-phosphate thymidylyltransferase, MAGNESIUM ION | | 著者 | Chang, A, Moretti, R, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2010-11-11 | | 公開日 | 2011-01-12 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Expanding the Nucleotide and Sugar 1-Phosphate Promiscuity of Nucleotidyltransferase RmlA via Directed Evolution.
J.Biol.Chem., 286, 2011
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3PKQ
 | | Q83D Variant of S. Enterica RmlA with dGTP | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, Glucose-1-phosphate thymidylyltransferase, ... | | 著者 | Chang, A, Moretti, R, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2010-11-11 | | 公開日 | 2011-01-12 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Expanding the Nucleotide and Sugar 1-Phosphate Promiscuity of Nucleotidyltransferase RmlA via Directed Evolution.
J.Biol.Chem., 286, 2011
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5ALC
 | | Ticagrelor antidote candidate Fab 72 in complex with ticagrelor | | 分子名称: | ANTI-TICAGRELOR FAB 72, HEAVY CHAIN, LIGHT CHAIN, ... | | 著者 | Buchanan, A, Newton, P, Pehrsson, S, Inghardt, T, Antonsson, T, Svensson, P, Sjogren, T, Oster, L, Janefeldt, A, Sandinge, A, Keyes, F, Austin, M, Spooner, J, Penney, M, Howells, G, Vaughan, T, Nylander, S. | | 登録日 | 2015-03-07 | | 公開日 | 2015-04-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and Functional Characterisation of a Specific Antidote for Ticagrelor.
Blood, 125, 2015
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5ALB
 | | Ticagrelor antidote candidate MEDI2452 in complex with ticagrelor | | 分子名称: | MEDI2452 HEAVY CHAIN, MEDI2452 LIGHT CHAIN, Ticagrelor | | 著者 | Buchanan, A, Newton, P, Pehrsson, S, Inghardt, T, Antonsson, T, Svensson, P, Sjogren, T, Oster, L, Janefeldt, A, Sandinge, A, Keyes, F, Austin, M, Spooner, J, Penney, M, Howells, G, Vaughan, T, Nylander, S. | | 登録日 | 2015-03-07 | | 公開日 | 2015-04-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Structural and Functional Characterisation of a Specific Antidote for Ticagrelor.
Blood, 125, 2015
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5DPT
 | | Crystal structure of PLEKHM1 LIR-fused human GABARAPL1_2-117 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Pleckstrin homology domain-containing family M member 1, Gamma-aminobutyric acid receptor-associated protein-like 1,Gamma-aminobutyric acid receptor-associated protein-like 1 | | 著者 | Ravichandran, A.C, Suzuki, H, Dobson, R.C.J. | | 登録日 | 2015-09-14 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural and functional analysis of the GABARAP interaction motif (GIM).
EMBO Rep., 18, 2017
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1Q09
 | | Crystal structure of the Zn(II) form of E. coli ZntR, a zinc-sensing transcriptional regulator (space group I4122) | | 分子名称: | SULFATE ION, ZINC ION, Zn(II)-responsive regulator of zntA | | 著者 | Changela, A, Chen, K, Xue, Y, Holschen, J, Outten, C.E, O'Halloran, T.V, Mondragon, A. | | 登録日 | 2003-07-15 | | 公開日 | 2003-09-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR
Science, 301, 2003
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1Q06
 | | Crystal structure of the Ag(I) form of E. coli CueR, a copper efflux regulator | | 分子名称: | SILVER ION, Transcriptional regulator cueR | | 著者 | Changela, A, Chen, K, Xue, Y, Holschen, J, Outten, C.E, O'Halloran, T.V, Mondragon, A. | | 登録日 | 2003-07-15 | | 公開日 | 2003-09-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR
Science, 301, 2003
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3RSC
 | | Crystal Structure of CalG2, Calicheamicin Glycosyltransferase, TDP and calicheamicin T0 bound form | | 分子名称: | CalG2, Calicheamicin T0, PHOSPHATE ION, ... | | 著者 | Chang, A, Helmich, K.E, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2011-05-02 | | 公開日 | 2011-08-10 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.
Proc.Natl.Acad.Sci.USA, 108, 2011
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1Q0A
 | | Crystal structure of the Zn(II) form of E. coli ZntR, a zinc-sensing transcriptional regulator (space group C222) | | 分子名称: | SULFATE ION, ZINC ION, Zn(II)-responsive regulator of zntA | | 著者 | Changela, A, Chen, K, Xue, Y, Holschen, J, Outten, C.E, O'Halloran, T.V, Mondragon, A. | | 登録日 | 2003-07-15 | | 公開日 | 2003-09-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR
Science, 301, 2003
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1Q08
 | | Crystal structure of the Zn(II) form of E. coli ZntR, a zinc-sensing transcriptional regulator, at 1.9 A resolution (space group P212121) | | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, ZINC ION, ... | | 著者 | Changela, A, Chen, K, Xue, Y, Holschen, J, Outten, C.E, O'Halloran, T.V, Mondragon, A. | | 登録日 | 2003-07-15 | | 公開日 | 2003-09-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR
Science, 301, 2003
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3TOS
 | | Crystal Structure of CalS11, Calicheamicin Methyltransferase | | 分子名称: | 1,2-ETHANEDIOL, CalS11, GLUTAMIC ACID, ... | | 著者 | Chang, A, Aceti, D.J, Beebe, E.T, Makino, S.-I, Wrobel, R.L, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2011-09-06 | | 公開日 | 2011-10-05 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal Structure of CalS11, Calicheamicin methyltransferase
To be Published
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1Q05
 | | Crystal structure of the Cu(I) form of E. coli CueR, a copper efflux regulator | | 分子名称: | COPPER (I) ION, Transcriptional regulator cueR | | 著者 | Changela, A, Chen, K, Xue, Y, Holschen, J, Outten, C.E, O'Halloran, T.V, Mondragon, A. | | 登録日 | 2003-07-15 | | 公開日 | 2003-09-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR
Science, 301, 2003
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5DPS
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3TSR
 | | X-ray structure of mouse ribonuclease inhibitor complexed with mouse ribonuclease 1 | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Ribonuclease inhibitor, ... | | 著者 | Chang, A, Lomax, J.E, Bingman, C.A, Raines, R.T, Phillips Jr, G.N. | | 登録日 | 2011-09-13 | | 公開日 | 2012-09-19 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1999 Å) | | 主引用文献 | Functional evolution of ribonuclease inhibitor: insights from birds and reptiles.
J.Mol.Biol., 426, 2014
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1Q07
 | | Crystal structure of the Au(I) form of E. coli CueR, a copper efflux regulator | | 分子名称: | GOLD ION, Transcriptional regulator cueR | | 著者 | Changela, A, Chen, K, Xue, Y, Holschen, J, Outten, C.E, O'Halloran, T.V, Mondragon, A. | | 登録日 | 2003-07-15 | | 公開日 | 2003-09-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR
Science, 301, 2003
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5DPR
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7YC6
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5DPW
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6B8M
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