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PDB: 207 件

6UT3
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X-ray structure of Thermococcus gammatolerans McrB AAA+ domain hexamer in P21 symmetry
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase subunit of restriction endonuclease, MAGNESIUM ION
著者Niu, Y, Hosford, C.J, Chappie, J.S.
登録日2019-10-29
公開日2020-10-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural asymmetry governs the assembly and GTPase activity of McrBC restriction complexes.
Nat Commun, 11, 2020
6UT4
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Cryo-EM structure of the asymmetric AAA+ domain hexamer from Thermococcus gammatolerans McrB
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase subunit of restriction endonuclease, MAGNESIUM ION
著者Niu, Y, Suzuki, H, Hosford, C.J, Chappie, J.S, Walz, T.
登録日2019-10-29
公開日2020-10-21
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural asymmetry governs the assembly and GTPase activity of McrBC restriction complexes.
Nat Commun, 11, 2020
6UT7
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Fitted model for the tetradecameric assembly of Thermococcus gammatolerans McrB AAA+ hexamers with bound McrC
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase subunit of restriction endonuclease, GUANOSINE-5'-DIPHOSPHATE, ...
著者Niu, Y, Suzuki, H, Hosford, C.J, Chappie, J.S, Walz, T.
登録日2019-10-29
公開日2020-10-21
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.26 Å)
主引用文献Structural asymmetry governs the assembly and GTPase activity of McrBC restriction complexes.
Nat Commun, 11, 2020
6UT5
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Cryo-EM structure of the Thermococcus gammatolerans McrBC complex
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase subunit of restriction endonuclease, GUANOSINE-5'-DIPHOSPHATE, ...
著者Niu, Y, Suzuki, H, Hosford, C.J, Chappie, J.S, Walz, T.
登録日2019-10-29
公開日2020-10-21
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.44 Å)
主引用文献Structural asymmetry governs the assembly and GTPase activity of McrBC restriction complexes.
Nat Commun, 11, 2020
6UT8
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Refined half-complex from tetradecameric assembly of Thermococcus gammatolerans McrB AAA+ hexamers with bound McrC
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase subunit of restriction endonuclease, GUANOSINE-5'-DIPHOSPHATE, ...
著者Niu, Y, Suzuki, H, Hosford, C.J, Chappie, J.S, Walz, T.
登録日2019-10-29
公開日2020-10-21
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Structural asymmetry governs the assembly and GTPase activity of McrBC restriction complexes.
Nat Commun, 11, 2020
6VJF
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The P-Loop K to A mutation of C. therm Vps1 GTPase-BSE
分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Putative sorting protein Vps1
著者Tornabene, B.A, Varlakhanova, N.V, Chappie, J.S, Ford, M.G.J.
登録日2020-01-15
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.472 Å)
主引用文献Structural and functional characterization of the dominant negative P-loop lysine mutation in the dynamin superfamily protein Vps1.
Protein Sci., 29, 2020
1XMA
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Structure of a transcriptional regulator from Clostridium thermocellum Cth-833
分子名称: MERCURY (II) ION, Predicted transcriptional regulator, UNKNOWN ATOM OR ION
著者Yang, H, Chen, L, Lee, D, Habel, J, Nguyen, J, Chang, S.-H, Kataeva, I, Xu, H, Chang, J, Zhao, M, Horanyi, P, Florence, Q, Zhou, W, Tempel, W, Lin, D, Praissman, J, Zhang, H, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Ljungdahl, L, Liu, Z.-J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-10-01
公開日2004-12-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Structure of a transcriptional regulator from Clostridium thermocellum Cth-833
To be published
1XRG
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Conserved hypothetical protein from Clostridium thermocellum Cth-2968
分子名称: Putative translation initiation inhibitor, yjgF family, UNKNOWN ATOM OR ION
著者Zhao, M, Chang, J, Habel, J, Kataeva, I, Xu, H, Chen, L, Lee, D, Nguyen, J, Chang, S.-H, Horanyi, P, Florence, Q, Zhou, W, Tempel, W, Lin, D, Zhang, H, Arendall III, W.B, Ljundahl, L, Liu, Z.-J, Rose, J, Richardson, J.S, Richardson, D.C, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-10-14
公開日2004-12-14
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Conserved hypothetical protein from Clostridium thermocellum Cth-2968
To be published
1XG7
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Conserved hypothetical protein Pfu-877259-001 from Pyrococcus furiosus
分子名称: hypothetical protein
著者Chang, J, Zhao, M, Horanyi, P, Xu, H, Yang, H, Liu, Z.-J, Chen, L, Zhou, W, Habel, J, Tempel, W, Lee, D, Lin, D, Chang, S.-H, Eneh, J.C, Hopkins, R.C, Jenney Jr, F.E, Lee, H.-S, Li, T, Poole II, F.L, Shah, C, Sugar, F.J, Chen, C.-Y, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Rose, J.P, Adams, M.W.W, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-09-16
公開日2004-11-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Conserved hypothetical protein Pfu-877259-001 from Pyrococcus furiosus
To be published
5N88
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Crystal structure of antibody bound to viral protein
分子名称: PC4 and SFRS1-interacting protein, VH59 antibody
著者Bao, L, Hannon, C, Cruz-Migoni, A, Ptchelkine, D, Sun, M.-y, Derveni, M, Bunjobpol, W, Chambers, J.S, Simmons, A, Phillips, S.E.V, Rabbitts, T.H.
登録日2017-02-23
公開日2017-12-20
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Intracellular immunization against HIV infection with an intracellular antibody that mimics HIV integrase binding to the cellular LEDGF protein.
Sci Rep, 7, 2017
1ZGH
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Methionyl-tRNA formyltransferase from Clostridium thermocellum
分子名称: Methionyl-tRNA formyltransferase, UNKNOWN ATOM OR ION
著者Yang, H, Kataeva, I, Xu, H, Zhao, M, Chang, J, Liu, Z, Chen, L, Tempel, W, Habel, J, Zhou, W, Lee, D, Lin, D, Chang, S, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Rose, J.P, Wang, B, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2005-04-21
公開日2005-05-03
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Methionyl-tRNA formyltransferase from Clostridium thermocellum
To be published
5K5N
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Crystal structure of GSK-3beta complexed with PF-04802367, a highly selective brain-penetrant kinase inhibitor
分子名称: 5-(3-chloranyl-4-methoxy-phenyl)-~{N}-[3-(1,2,4-triazol-1-yl)propyl]-1,3-oxazole-4-carboxamide, Glycogen synthase kinase-3 beta, SULFATE ION
著者Kurumbail, R.G, Chang, J.S.
登録日2016-05-23
公開日2016-09-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging.
Angew.Chem.Int.Ed.Engl., 55, 2016
7XZR
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Crystal structure of TNIK-AMPPNP-thiopeptide TP15 complex
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION, ...
著者Hamada, K, Vinogradov, A.A, Zhang, Y, Chang, J.S, Nishimura, H, Goto, Y, Onaka, H, Suga, H, Ogata, K, Sengoku, T.
登録日2022-06-03
公開日2022-10-26
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献De Novo Discovery of Thiopeptide Pseudo-natural Products Acting as Potent and Selective TNIK Kinase Inhibitors.
J.Am.Chem.Soc., 144, 2022
7XZQ
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Crystal structure of TNIK-thiopeptide TP1 complex
分子名称: 1,4-BUTANEDIOL, TRAF2 and NCK-interacting protein kinase, thiopeptide TP1
著者Hamada, K, Vinogradov, A.A, Zhang, Y, Chang, J.S, Nishimura, H, Goto, Y, Onaka, H, Suga, H, Ogata, K, Sengoku, T.
登録日2022-06-03
公開日2022-10-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献De Novo Discovery of Thiopeptide Pseudo-natural Products Acting as Potent and Selective TNIK Kinase Inhibitors.
J.Am.Chem.Soc., 144, 2022
6C30
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Mycobacterium smegmatis RimJ (apo form)
分子名称: CHLORIDE ION, GLYCEROL, GNAT family acetyltransferase
著者Favrot, L, Hegde, S.S, Blanchard, J.S.
登録日2018-01-09
公開日2019-01-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.397 Å)
主引用文献Structural Characterization of Mycobacterium smegmatis RimJ, an N-acetyltransferase protein
To Be Published
1XE1
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Hypothetical Protein From Pyrococcus Furiosus Pfu-880080-001
分子名称: SULFATE ION, hypothetical protein PF0907
著者Chang, J.C, Zhao, M, Zhou, W, Liu, Z.J, Tempel, W, Arendall III, W.B, Chen, L, Lee, D, Habel, J.E, Rose, J.P, Richardson, J.S, Richardson, D.C, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-09-08
公開日2004-09-21
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Hypothetical Protein From Pyrococcus Furiosus Pfu-880080-001
To be published
1XHO
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Chorismate mutase from Clostridium thermocellum Cth-682
分子名称: Chorismate mutase, UNKNOWN ATOM OR ION
著者Xu, H, Chen, L, Lee, D, Habel, J.E, Nguyen, J, Chang, S.-H, Kataeva, I, Chang, J, Zhao, M, Yang, H, Horanyi, P, Florence, Q, Tempel, W, Zhou, W, Lin, D, Zhang, H, Praissman, J, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Ljungdahl, L, Liu, Z.-J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-09-20
公開日2004-11-23
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Away from the edge II: in-house Se-SAS phasing with chromium radiation.
Acta Crystallogr.,Sect.D, 61, 2005
1YEM
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Conserved hypothetical protein Pfu-838710-001 from Pyrococcus furiosus
分子名称: Conserved hypothetical protein Pfu-838710-001, PLATINUM (II) ION, UNKNOWN ATOM OR ION
著者Yang, H, Chang, J, Shah, A, Ng, J.D, Liu, Z.-J, Chen, L, Lee, D, Tempel, W, Praissman, J.L, Lin, D, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Jenney Jr, F.E, Adams, M.W.W, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-12-28
公開日2005-01-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Conserved hypothetical protein Pfu-838710-001 from Pyrococcus furiosus
To be published
1XX7
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Conserved hypothetical protein from Pyrococcus furiosus Pfu-403030-001
分子名称: NICKEL (II) ION, UNKNOWN ATOM OR ION, oxetanocin-like protein
著者Chen, L, Tempel, W, Habel, J, Zhou, W, Nguyen, D, Chang, S.-H, Lee, D, Kelley, L.-L.C, Dillard, B.D, Liu, Z.-J, Bridger, S, Eneh, J.C, Hopkins, R.C, Jenney Jr, F.E, Lee, H.-S, Li, T, Poole II, F.L, Shah, C, Sugar, F.J, Adams, M.W.W, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-11-04
公開日2004-12-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.261 Å)
主引用文献Conserved hypothetical protein from Pyrococcus furiosus Pfu-403030-001
To be published
6C32
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Mycobacterium smegmatis RimJ with AcCoA
分子名称: ACETYL COENZYME *A, Acetyltransferase, GNAT family protein
著者Favrot, L, Hegde, S.S, Blanchard, J.S.
登録日2018-01-09
公開日2019-01-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.898 Å)
主引用文献Structural Characterization of Mycobacterium smegmatis RimJ, an N-acetyltransferase protein
To Be Published
6C5D
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N-terminal domain of Helicobacter pylori LlaJI.R1
分子名称: LlaJI.R1
著者Hosford, C.J, Chappie, J.S.
登録日2018-01-16
公開日2018-06-27
最終更新日2018-08-08
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献The crystal structure of theHelicobacter pyloriLlaJI.R1 N-terminal domain provides a model for site-specific DNA binding.
J. Biol. Chem., 293, 2018
1XI3
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Thiamine phosphate pyrophosphorylase from Pyrococcus furiosus Pfu-1255191-001
分子名称: NICKEL (II) ION, SULFATE ION, Thiamine phosphate pyrophosphorylase, ...
著者Zhou, W, Chen, L, Tempel, W, Liu, Z.-J, Habel, J, Lee, D, Lin, D, Chang, S.-H, Dillard, B.D, Eneh, J.C, Hopkins, R.C, Jenney Jr, F.E, Kelley, L.-L.C, Lee, H.-S, Li, T, Poole II, F.L, Shah, C, Sugar, F.J, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Rose, J.P, Adams, M.W.W, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-09-21
公開日2004-09-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Thiamine phosphate pyrophosphorylase from Pyrococcus furiosus Pfu-1255191-001
To be published
1XI9
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Alanine aminotransferase from Pyrococcus furiosus Pfu-1397077-001
分子名称: PYRIDOXAL-5'-PHOSPHATE, putative transaminase
著者Zhou, W, Tempel, W, Shah, A, Chen, L, Liu, Z.-J, Lee, D, Lin, D, Chang, S.-H, Brereton, P.S, Izumi, M, Jenney Jr, F.E, Lee, H.-S, Poole II, F.L, Shah, C, Sugar, F.J, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Rose, J.P, Adams, M.W.W, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-09-21
公開日2004-11-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Alanine aminotransferase from Pyrococcus furiosus Pfu-1397077-001
To be published
6C37
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Mycobacterium smegmatis RimJ in complex with CoA-disulfide
分子名称: Acetyltransferase, GNAT family protein, [[(2~{S},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3~{R})-4-[[3-[2-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyldisulfanyl]ethylamino]-3-oxidanylidene-propyl]amino]-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl] hydrogen phosphate
著者Favrot, L, Hegde, S.S, Blanchard, J.S.
登録日2018-01-09
公開日2019-01-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.696 Å)
主引用文献Structural Characterization of Mycobacterium smegmatis RimJ, an N-acetyltransferase protein
To Be Published
6DJQ
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Vps1 GTPase-BSE fusion complexed with GDP.AlF4-
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SODIUM ION, ...
著者Varlakhanova, N.V, Brady, T.M, Tornabene, B.A, Hosford, C.J, Chappie, J.S, Ford, M.G.J.
登録日2018-05-25
公開日2018-08-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of the fungal dynamin-related protein Vps1 reveal a unique, open helical architecture.
J. Cell Biol., 217, 2018

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件を2024-09-04に公開中

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