6AE3
 
 | | Crystal structure of GSK3beta complexed with Morin | | 分子名称: | 2-[2,4-bis(oxidanyl)phenyl]-3,5,7-tris(oxidanyl)chromen-4-one, GLYCEROL, Glycogen synthase kinase-3 beta | | 著者 | Kim, K.L, Cha, J.S, Kim, J.S, Ahn, J.S, Ha, N.C, Cho, H.S. | | 登録日 | 2018-08-03 | | 公開日 | 2018-09-19 | | 最終更新日 | 2018-10-03 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Crystal structure of GSK3 beta in complex with the flavonoid, morin
Biochem. Biophys. Res. Commun., 504, 2018
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5Z9G
 | | Crystal structure of KAI2 | | 分子名称: | Probable esterase KAI2 | | 著者 | Kim, K.L, Cha, J.S, Soh, M.S, Cho, H.S. | | 登録日 | 2018-02-03 | | 公開日 | 2018-08-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | A missense allele of KARRIKIN-INSENSITIVE2 impairs ligand-binding and downstream signaling in Arabidopsis thaliana.
J. Exp. Bot., 69, 2018
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5Z9H
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7E5B
 | | Crystal structure of ASC PYD Domain and Rb-B7 | | 分子名称: | Apoptosis-associated speck-like protein containing a CARD, GLYCEROL, Repebody (Rb-B7) | | 著者 | Cho, H.S, Cha, J.S. | | 登録日 | 2021-02-18 | | 公開日 | 2022-03-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Oligomeric states of ASC specks regulate inflammatory responses by inflammasome in the extracellular space.
Cell Death Discov, 9, 2023
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5FJG
 | | The crystal structure of light-driven chloride pump ClR in pH 4.5. | | 分子名称: | ANHYDRORETINOL, CHLORIDE ION, CHLORIDE PUMPING RHODOPSIN, ... | | 著者 | Kim, K.L, Kwon, S.K, Jun, S.H, Cha, J.S, Kim, H.Y, Kim, J.H, Cho, H.S. | | 登録日 | 2015-10-07 | | 公開日 | 2016-11-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Crystal Structure of Light-Driven Chloride Pump Clr in Ph 4.5.
To be Published
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5G2C
 | | The crystal structure of light-driven chloride pump ClR (T102D) mutant at pH 4.5. | | 分子名称: | CHLORIDE ION, CHLORIDE PUMPING RHODOPSIN, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Kim, K.L, Kwon, S.K, Jun, S.H, Cha, J.S, Kim, H.Y, Kim, J.H, Cho, H.S. | | 登録日 | 2016-04-07 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Crystal Structure and Functional Characterization of a Light-Driven Chloride Pump Having an Ntq Motif.
Nat.Commun., 7, 2016
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5G54
 | | The crystal structure of light-driven chloride pump ClR at pH 4.5 | | 分子名称: | CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ... | | 著者 | Kim, K.L, Kwon, S.K, Jun, S.H, Cha, J.S, Kim, H.Y, Kim, J.H, Cho, H.S. | | 登録日 | 2016-05-19 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure and Functional Characterization of a Light-Driven Chloride Pump Having an Ntq Motif.
Nat.Commun., 7, 2016
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5G28
 | | The crystal structure of light-driven chloride pump ClR at pH 6.0. | | 分子名称: | CHLORIDE ION, CHLORIDE PUMPING RHODOPSIN, OLEIC ACID, ... | | 著者 | Kim, K.L, Kwon, S.K, Jun, S.H, Cha, J.S, Kim, H.Y, Kim, J.H, Cho, H.S. | | 登録日 | 2016-04-07 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Crystal Structure and Functional Characterization of a Light-Driven Chloride Pump Having an Ntq Motif.
Nat.Commun., 7, 2016
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5G2D
 | | The crystal structure of light-driven chloride pump ClR (T102N) mutant at pH 4.5. | | 分子名称: | CHLORIDE ION, CHLORIDE PUMP RHODOPSIN, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Kim, K.L, Kwon, S.K, Jun, S.H, Cha, J.S, Kim, H.Y, Kim, J.H, Cho, H.S. | | 登録日 | 2016-04-07 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure and Functional Characterization of a Light-Driven Chloride Pump Having an Ntq Motif.
Nat.Commun., 7, 2016
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5G2A
 | | The crystal structure of light-driven chloride pump ClR at pH 6.0 with Bromide ion. | | 分子名称: | BROMIDE ION, CHLORIDE PUMPING RHODOPSIN, RETINAL | | 著者 | Kim, K.L, Kwon, S.K, Jun, S.H, Cha, J.S, Kim, H.Y, Kim, J.H, Cho, H.S. | | 登録日 | 2016-04-07 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Crystal Structure and Functional Characterization of a Light-Driven Chloride Pump Having an Ntq Motif.
Nat.Commun., 7, 2016
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6KF9
 | | Cryo-EM structure of Thermococcus kodakarensis RNA polymerase | | 分子名称: | DNA (27-MER), DNA (5'-D(P*TP*CP*GP*GP*TP*AP*AP*TP*CP*AP*CP*GP*CP*TP*CP*C)-3'), DNA-directed RNA polymerase subunit, ... | | 著者 | Jun, S.-H, Hyun, J, Jeong, H, Cha, J.S, Kim, H, Bartlett, M.S, Cho, H.-S, Murakami, K.S. | | 登録日 | 2019-07-07 | | 公開日 | 2020-07-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.79 Å) | | 主引用文献 | Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase.
Nat Commun, 11, 2020
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6KF3
 | | Cryo-EM structure of Thermococcus kodakarensis RNA polymerase | | 分子名称: | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit A'', DNA-directed RNA polymerase subunit D, ... | | 著者 | Jun, S.-H, Hyun, J, Jeong, H, Cha, J.S, Kim, H, Bartlett, M.S, Cho, H.-S, Murakami, K.S. | | 登録日 | 2019-07-06 | | 公開日 | 2020-07-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase.
Nat Commun, 11, 2020
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6KF4
 | | Cryo-EM structure of Thermococcus kodakarensis RNA polymerase | | 分子名称: | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit A'', DNA-directed RNA polymerase subunit D, ... | | 著者 | Jun, S.-H, Hyun, J, Jeong, H, Cha, J.S, Kim, H, Bartlett, M.S, Cho, H.-S, Murakami, K.S. | | 登録日 | 2019-07-06 | | 公開日 | 2020-07-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.97 Å) | | 主引用文献 | Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase.
Nat Commun, 11, 2020
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6LBX
 | | Crystal structure of HER2 Domain IV and Rb-H2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor tyrosine-protein kinase erbB-2, Repebody (Rb-H2) | | 著者 | Cho, H.S, Cha, J.S. | | 登録日 | 2019-11-15 | | 公開日 | 2020-11-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Computationally-guided design and affinity improvement of a protein binder targeting a specific site on HER2
Comput Struct Biotechnol J, 19, 2021
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6N0S
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6NJX
 | | C-terminal region of the Xanthomonas campestris pv. campestris OLD protein phased with mercury | | 分子名称: | IODIDE ION, MERCURY (II) ION, Xcc_ctr_Hg | | 著者 | Schiltz, C.J, Lee, A, Partlow, E.A, Hosford, C.J, Chappie, J.S. | | 登録日 | 2019-01-04 | | 公開日 | 2019-08-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage.
Nucleic Acids Res., 47, 2019
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6NK8
 | | C-terminal region of the Burkholderia pseudomallei OLD protein | | 分子名称: | Class 2 OLD family nuclease, MAGNESIUM ION | | 著者 | Schiltz, C.J, Lee, A, Partlow, E.A, Hosford, C.J, Chappie, J.S. | | 登録日 | 2019-01-05 | | 公開日 | 2019-08-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage.
Nucleic Acids Res., 47, 2019
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6NJW
 | | C-terminal region of the Xanthomonas campestris pv. campestris OLD protein phased with platinum | | 分子名称: | IODIDE ION, MAGNESIUM ION, PLATINUM (II) ION, ... | | 著者 | Schiltz, C.J, Lee, A, Partlow, E.A, Hosford, C.J, Chappie, J.S. | | 登録日 | 2019-01-04 | | 公開日 | 2019-08-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage.
Nucleic Acids Res., 47, 2019
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6NJV
 | | C-terminal region of the Xanthomonas campestris pv. campestris OLD protein phased with iodine | | 分子名称: | IODIDE ION, MAGNESIUM ION, Xcc_CTR_I | | 著者 | Schiltz, C.J, Lee, A, Partlow, E.A, Hosford, C.J, Chappie, J.S. | | 登録日 | 2019-01-04 | | 公開日 | 2019-08-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage.
Nucleic Acids Res., 47, 2019
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6OWO
 | | CRYO-EM STRUCTURE OF PHOSPHORYLATED AP-2 CORE BOUND TO NECAP | | 分子名称: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | | 著者 | Partlow, E.A, Baker, R.W, Beacham, G.M, Chappie, J.S, Leschziner, A.E, Hollopeter, G. | | 登録日 | 2019-05-10 | | 公開日 | 2019-09-11 | | 最終更新日 | 2020-01-08 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex.
Elife, 8, 2019
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8E4Y
 | | Cryo-EM structure of human glycerol-3-phosphate acyltransferase 1 (GPAT1) in complex with 2-oxohexadecyl-CoA | | 分子名称: | (2R)-2-hydroxy-3-(phosphonooxy)propyl hexadecanoate, Glycerol-3-phosphate acyltransferase 1, mitochondrial, ... | | 著者 | Johnson, Z.L, Wasilko, D.J, Ammirati, M, Chang, J.S, Han, S, Wu, H. | | 登録日 | 2022-08-19 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis of the acyl-transfer mechanism of human GPAT1.
Nat.Struct.Mol.Biol., 30, 2023
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8E50
 | | Cryo-EM structure of human glycerol-3-phosphate acyltransferase 1 (GPAT1) in complex with CoA and palmitoyl-LPA | | 分子名称: | (2R)-2-hydroxy-3-(phosphonooxy)propyl hexadecanoate, COENZYME A, Glycerol-3-phosphate acyltransferase 1, ... | | 著者 | Wasilko, D.J, Johnson, Z.L, Ammirati, M, Chang, J.S, Han, S, Wu, H. | | 登録日 | 2022-08-19 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | | 主引用文献 | Structural basis of the acyl-transfer mechanism of human GPAT1.
Nat.Struct.Mol.Biol., 30, 2023
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6P0F
 | | N-terminal domain of Thermococcus Gammatolerans McrB | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, AMMONIUM ION, GTPase subunit of restriction endonuclease, ... | | 著者 | Hosford, C.J, Chappie, J.S. | | 登録日 | 2019-05-17 | | 公開日 | 2019-12-18 | | 最終更新日 | 2020-01-29 | | 実験手法 | X-RAY DIFFRACTION (1.683 Å) | | 主引用文献 | The structure of theThermococcus gammatoleransMcrB N-terminal domain reveals a new mode of substrate recognition and specificity among McrB homologs.
J.Biol.Chem., 295, 2020
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6P0G
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7XZR
 | | Crystal structure of TNIK-AMPPNP-thiopeptide TP15 complex | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION, ... | | 著者 | Hamada, K, Vinogradov, A.A, Zhang, Y, Chang, J.S, Nishimura, H, Goto, Y, Onaka, H, Suga, H, Ogata, K, Sengoku, T. | | 登録日 | 2022-06-03 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | De Novo Discovery of Thiopeptide Pseudo-natural Products Acting as Potent and Selective TNIK Kinase Inhibitors.
J.Am.Chem.Soc., 144, 2022
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