9AUC
 
 | | Human Amylin1 Receptor in Complex with Gs and human Calcitonin Gene-Related Peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Calcitonin gene-related peptide 1, ... | | 著者 | Cao, J, Belousoff, M.J, Wootten, D.L, Sexton, P.M. | | 登録日 | 2024-02-28 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Cryo-EM Structure of the Human Amylin 1 Receptor in Complex with CGRP and Gs Protein.
Biochemistry, 63, 2024
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8F2B
 | | Amylin 3 Receptor in complex with Gs and Pramlintide analogue peptide San45 | | 分子名称: | (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Cao, J, Sexton, P.M, Wootten, D.L, Belousoff, M.J. | | 登録日 | 2022-11-07 | | 公開日 | 2023-08-02 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2 Å) | | 主引用文献 | Structural insight into selectivity of amylin and calcitonin receptor agonists.
Nat.Chem.Biol., 20, 2024
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8F0J
 | | Calcitonin Receptor in complex with Gs and Pramlintide analogue peptide San45 | | 分子名称: | (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Cao, J, Sexton, P.M, Wootten, D.L, Belousoff, M.J. | | 登録日 | 2022-11-03 | | 公開日 | 2023-08-02 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (2 Å) | | 主引用文献 | Structural insight into selectivity of amylin and calcitonin receptor agonists.
Nat.Chem.Biol., 20, 2024
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8F0K
 | | Human Amylin3 Receptor in complex with Gs and Pramlintide analogue peptide San385 | | 分子名称: | (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Cao, J, Sexton, P.M, Wootten, D.L. | | 登録日 | 2022-11-03 | | 公開日 | 2023-08-02 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (1.9 Å) | | 主引用文献 | Structural insight into selectivity of amylin and calcitonin receptor agonists.
Nat.Chem.Biol., 20, 2024
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8F2A
 | | Human Amylin3 Receptor in complex with Gs and Pramlintide analogue peptide San385 (Cluster 5 conformation) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcitonin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Cao, J, Sexton, P.M, Wootten, D.L, Radostin, D. | | 登録日 | 2022-11-07 | | 公開日 | 2023-08-02 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | Structural insight into selectivity of amylin and calcitonin receptor agonists.
Nat.Chem.Biol., 20, 2024
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7TZF
 | | Human Amylin3 Receptor in complex with Gs and rat amylin peptide | | 分子名称: | (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M. | | 登録日 | 2022-02-15 | | 公開日 | 2022-03-23 | | 最終更新日 | 2022-04-06 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | A structural basis for amylin receptor phenotype.
Science, 375, 2022
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7TYF
 | | Human Amylin1 Receptor in complex with Gs and rat amylin peptide | | 分子名称: | (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M. | | 登録日 | 2022-02-13 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | A structural basis for amylin receptor phenotype.
Science, 375, 2022
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7TYH
 | | Human Amylin2 Receptor in complex with Gs and human calcitonin peptide | | 分子名称: | Calcitonin, Calcitonin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M. | | 登録日 | 2022-02-13 | | 公開日 | 2022-03-23 | | 最終更新日 | 2022-04-06 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A structural basis for amylin receptor phenotype.
Science, 375, 2022
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7TYW
 | | Human Amylin1 Receptor in complex with Gs and salmon calcitonin peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Calcitonin receptor, ... | | 著者 | Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M. | | 登録日 | 2022-02-14 | | 公開日 | 2022-03-23 | | 最終更新日 | 2022-04-06 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | A structural basis for amylin receptor phenotype.
Science, 375, 2022
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7TYO
 | | Calcitonin receptor in complex with Gs and human calcitonin peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Calcitonin, ... | | 著者 | Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M. | | 登録日 | 2022-02-14 | | 公開日 | 2022-03-23 | | 最終更新日 | 2022-04-06 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | A structural basis for amylin receptor phenotype.
Science, 375, 2022
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7TYY
 | | Human Amylin2 Receptor in complex with Gs and salmon calcitonin peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Calcitonin receptor, ... | | 著者 | Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M. | | 登録日 | 2022-02-14 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | A structural basis for amylin receptor phenotype.
Science, 375, 2022
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7TYL
 | | Calcitonin Receptor in complex with Gs and rat amylin peptide, bypass motif | | 分子名称: | Calcitonin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M. | | 登録日 | 2022-02-13 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A structural basis for amylin receptor phenotype.
Science, 375, 2022
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7TYN
 | | Calcitonin Receptor in complex with Gs and salmon calcitonin peptide | | 分子名称: | (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M. | | 登録日 | 2022-02-13 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | A structural basis for amylin receptor phenotype.
Science, 375, 2022
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7TYX
 | | Human Amylin2 Receptor in complex with Gs and rat amylin peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Calcitonin receptor, ... | | 著者 | Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M. | | 登録日 | 2022-02-14 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.55 Å) | | 主引用文献 | A structural basis for amylin receptor phenotype.
Science, 375, 2022
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7TYI
 | | Calcitonin Receptor in complex with Gs and rat amylin peptide, CT-like state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcitonin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M. | | 登録日 | 2022-02-13 | | 公開日 | 2022-03-30 | | 最終更新日 | 2022-04-06 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A structural basis for amylin receptor phenotype.
Science, 375, 2022
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7DNO
 | | Characterization of Peptide Ligands Against WDR5 Isolated Using Phage Display Technique | | 分子名称: | CYS-ARG-THR-LEU-PRO-PHE, WD repeat-containing protein 5 | | 著者 | Cao, J, Cao, D, Xiong, B, Li, Y, Fan, T. | | 登録日 | 2020-12-10 | | 公開日 | 2021-02-10 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Phage-Display Based Discovery and Characterization of Peptide Ligands against WDR5.
Molecules, 26, 2021
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3ZYV
 | | Crystal structure of the mouse liver Aldehyde Oxidase 3 (mAOX3) | | 分子名称: | AOX3, DIOXOTHIOMOLYBDENUM(VI) ION, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Trincao, J, Coelho, C, Mahro, M, Rodrigues, D, Terao, M, Garattini, E, Leimkuehler, S, Romao, M.J. | | 登録日 | 2011-08-27 | | 公開日 | 2012-09-05 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.545 Å) | | 主引用文献 | The First Mammalian Aldehyde Oxidase Crystal Structure: Insights Into Substrate Specificity.
J.Biol.Chem., 287, 2012
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1S97
 | | DPO4 with GT mismatch | | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*TP*G)-3', 5'-D(*T*TP*CP*AP*GP*TP*AP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', ... | | 著者 | Trincao, J, Johnson, R.E, Wolfle, W.T, Escalante, C.R, Prakash, S, Prakash, L, Aggarwal, A.K. | | 登録日 | 2004-02-03 | | 公開日 | 2004-04-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Dpo4 is hindered in extending a G.T mismatch by a reverse wobble
Nat.Struct.Mol.Biol., 11, 2004
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1S9F
 | | DPO with AT matched | | 分子名称: | 2',3'-DIDEOXYCYTOSINE-5'-DIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*TP*A)-3', 5'-D(*T*TP*CP*AP*GP*TP*AP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', ... | | 著者 | Trincao, J, Johnson, R.E, Wolfle, W.T, Escalante, C.R, Prakash, S, Prakash, L, Aggarwal, A.K. | | 登録日 | 2004-02-04 | | 公開日 | 2005-02-15 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Dpo4 is hindered in extending a G.T mismatch by a reverse wobble
Nat.Struct.Mol.Biol., 11, 2004
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8QPH
 | | Crystal structure of Lymantria dispar CPV14 polyhedra 14 crystals | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Polyhedrin | | 著者 | Trincao, J, Warren, A, Crawshaw, A, Sutton, G, Stuart, D, Evans, G. | | 登録日 | 2023-10-02 | | 公開日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | | 主引用文献 | VMXm - sub-micron microfocus beamline for macromolecular crystallography at Diamond Light Source
To Be Published
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8QQC
 | | Crystal structure of Lymantria dispar CPV14 polyhedra single crystal | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Polyhedrin | | 著者 | Trincao, J, Warren, A, Crawshaw, A, Sutton, G, Stuart, D, Evans, G. | | 登録日 | 2023-10-04 | | 公開日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | VMXm - sub-micron microfocus beamline for macromolecular crystallography at Diamond Light Source
To Be Published
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1JIH
 | | Yeast DNA Polymerase ETA | | 分子名称: | DNA Polymerase ETA | | 著者 | Trincao, J, Johnson, R.E, Escalante, C.R, Prakash, S, Prakash, L, Aggarwal, A.K. | | 登録日 | 2001-07-02 | | 公開日 | 2002-01-09 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structure of the catalytic core of S. cerevisiae DNA polymerase eta: implications for translesion DNA synthesis
Mol.Cell, 8, 2001
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2P1E
 | | Crystal structure of the Leishmania infantum glyoxalase II with D-Lactate at the active site | | 分子名称: | Glyoxalase II, LACTIC ACID, SPERMIDINE, ... | | 著者 | Trincao, J, Barata, L, Najmudin, S, Bonifacio, C, Romao, M.J. | | 登録日 | 2007-03-05 | | 公開日 | 2008-01-15 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Catalysis and Structural Properties of Leishmania infantum Glyoxalase II: Trypanothione Specificity and Phylogeny.
Biochemistry, 47, 2008
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2P18
 | | Crystal structure of the Leishmania infantum glyoxalase II | | 分子名称: | ACETIC ACID, Glyoxalase II, SPERMIDINE, ... | | 著者 | Trincao, J, Barata, L, Najmudin, S, Bonifacio, C, Romao, M.J. | | 登録日 | 2007-03-02 | | 公開日 | 2008-01-15 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Catalysis and Structural Properties of Leishmania infantum Glyoxalase II: Trypanothione Specificity and Phylogeny.
Biochemistry, 47, 2008
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2QW0
 | | 4-Chlorobenzoyl-CoA Ligase/Synthetase, I303A mutation, bound to 3,4 Dichlorobenzoate | | 分子名称: | 3,4-dichlorobenzoate, 4-Chlorobenzoate CoA Ligase | | 著者 | Wu, R, Reger, A.S, Cao, J, Gulick, A.M, Dunaway-Mariano, D. | | 登録日 | 2007-08-09 | | 公開日 | 2007-12-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Rational redesign of the 4-chlorobenzoate binding site of 4-chlorobenzoate: coenzyme a ligase for expanded substrate range.
Biochemistry, 46, 2007
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