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PDB: 60 件

4UCJ
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X-ray structure and activities of an essential Mononegavirales L- protein domain
分子名称: RNA-DIRECTED RNA POLYMERASE L, SULFATE ION, ZINC ION
著者Paesen, G.C, Collet, A, Sallamand, C, Debart, F, Vasseur, J.J, Canard, B, Decroly, E, Grimes, J.M.
登録日2014-12-03
公開日2015-11-18
最終更新日2019-04-24
実験手法X-RAY DIFFRACTION (3.26 Å)
主引用文献X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain.
Nat.Commun., 6, 2015
4UD0
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X-ray structure and activities of an essential Mononegavirales L- protein domain
分子名称: RNA-DIRECTED RNA POLYMERASE L, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
著者Paesen, G.C, Collet, A, Sallamand, C, Debart, F, Vasseur, J.J, Canard, B, Decroly, E, Grimes, J.M.
登録日2014-12-05
公開日2015-11-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain.
Nat.Commun., 6, 2015
3CDU
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Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with a pyrophosphate
分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
著者Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B.
登録日2008-02-27
公開日2008-07-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases
J.Virol., 82, 2008
3CDW
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Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with protein primer VPg and a pyrophosphate
分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
著者Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B.
登録日2008-02-27
公開日2008-07-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases
J.Virol., 82, 2008
2XYV
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Crystal structure of the nsp16 nsp10 SARS coronavirus complex
分子名称: CHLORIDE ION, MAGNESIUM ION, NON-STRUCTURAL PROTEIN 10, ...
著者Decroly, E, Debarnot, C, Ferron, F, Bouvet, M, Coutard, B, Imbert, I, Gluais, L, Papageorgiou, N, Ortiz-Lombardia, M, Lescar, J, Canard, B.
登録日2010-11-19
公開日2011-10-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex.
Plos Pathog., 7, 2011
2XYQ
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Crystal structure of the nsp16 nsp10 SARS coronavirus complex
分子名称: CHLORIDE ION, MAGNESIUM ION, NON-STRUCTURAL PROTEIN 10, ...
著者Decroly, E, Debarnot, C, Ferron, F, Bouvet, M, Coutard, B, Imbert, I, Gluais, L, Papageorgiou, N, Ortiz-Lombardia, M, Lescar, J, Canard, B.
登録日2010-11-18
公開日2011-10-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex.
Plos Pathog., 7, 2011
2XYR
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Crystal structure of the nsp16 nsp10 SARS coronavirus complex
分子名称: CHLORIDE ION, MAGNESIUM ION, NON-STRUCTURAL PROTEIN 10, ...
著者Decroly, E, Debarnot, C, Ferron, F, Bouvet, M, Coutard, B, Imbert, I, Gluais, L, Papageorgiou, N, Ortiz-Lombardia, M, Lescar, J, Canard, B.
登録日2010-11-18
公開日2011-10-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex.
Plos Pathog., 7, 2011
5NFY
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SARS-CoV nsp10/nsp14 dynamic complex
分子名称: DI(HYDROXYETHYL)ETHER, Polyprotein 1ab, ZINC ION
著者Ferron, F, Gluais, L, Vonrhein, C, Bricogne, G, Canard, B, Imbert, I.
登録日2017-03-16
公開日2018-01-10
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (3.382 Å)
主引用文献Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7OA4
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Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound L-742,001
分子名称: (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, FORMIC ACID, MANGANESE (II) ION, ...
著者Feracci, M, Hernandez, S, Vincentelli, R, Ferron, F, Reguera, J, Canard, B, Alvarez, K.
登録日2021-04-19
公開日2022-08-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound L-742,001
To Be Published
4C6A
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High Resolution Structure of the Nucleoside diphosphate kinase
分子名称: DI(HYDROXYETHYL)ETHER, NUCLEOSIDE DIPHOSPHATE KINASE, CYTOSOLIC
著者Priet, S, Ferron, F, Alvarez, K, Verron, M, Canard, B.
登録日2013-09-18
公開日2013-11-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Enzymatic Synthesis of Acyclic Nucleoside Thiophosphonate Diphosphates: Effect of the Alpha-Phosphorus Configuration on HIV-1 RT Activity.
Antiviral Res., 117, 2015
4CP5
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ndpK in complex with (Rp)-SPMPApp
分子名称: NUCLEOSIDE DIPHOSPHATE KINASE, CYTOSOLIC, [[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-sulfanyl-phosphoryl] phosphono hydrogen phosphate
著者Priet, S, Ferron, F, Alvarez, K, Verron, M, Canard, B.
登録日2014-01-31
公開日2015-02-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Enzymatic Synthesis of Acyclic Nucleoside Thiophosphonate Diphosphates: Effect of the Alpha-Phosphorus Configuration on HIV-1 RT Activity.
Antiviral Res., 117, 2015
7PLR
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Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound Baloxavir
分子名称: Baloxavir acid, FORMIC ACID, GLYCEROL, ...
著者Feracci, M, Hernandez, S, Vincentelli, R, Ferron, F, Reguera, J, Canard, B, Alvarez, K.
登録日2021-09-01
公開日2022-09-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound Baloxavir
To Be Published
2CKW
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The 2.3 A resolution structure of the Sapporo virus RNA dependant RNA polymerase.
分子名称: RNA-DIRECTED RNA POLYMERASE
著者Fullerton, S.W.B, Tucker, P.A, Rohayem, J, Coutard, B, Gebhardt, J, Gorbalenya, A, Canard, B.
登録日2006-04-24
公開日2006-11-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Functional Characterization of Sapovirus RNA-Dependent RNA Polymerase.
J.Virol., 81, 2007
2H85
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Crystal Structure of Nsp 15 from SARS
分子名称: Putative orf1ab polyprotein
著者Ricagno, S, Egloff, M.P, Ulferts, R, Coutard, B, Nurizzo, D, Campanacci, V, Cambillau, C, Ziebuhr, J, Canard, B.
登録日2006-06-06
公開日2006-08-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure and mechanistic determinants of SARS coronavirus nonstructural protein 15 define an endoribonuclease family.
Proc.Natl.Acad.Sci.Usa, 103, 2006
3OV9
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Structure of the Nucleoprotein from Rift Valley Fever Virus
分子名称: NITRITE ION, Nucleoprotein, SODIUM ION
著者Ferron, F, Danek, E.I, Li, Z, Luo, D, Wong, Y.H, Coutard, B, Lantez, V, Charrel, R, Canard, B, Walz, T, Lescar, J.
登録日2010-09-16
公開日2011-05-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes
Plos Pathog., 7, 2011
3OUO
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Structure of the Nucleoprotein from Rift Valley Fever Virus
分子名称: NITRITE ION, Nucleoprotein
著者Ferron, F, Danek, E.I, Li, Z, Luo, D, Wong, Y.H, Coutard, B, Lantez, V, Charrel, R, Canard, B, Walz, T, Lescar, J.
登録日2010-09-15
公開日2011-05-25
最終更新日2013-08-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes
Plos Pathog., 7, 2011
3Q3X
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Crystal structure of the main protease (3C) from human enterovirus B EV93
分子名称: GLYCEROL, HEVB EV93 3C protease, MAGNESIUM ION
著者Costenaro, L, Sola, M, Coutard, B, Norder, H, Canard, B, Coll, M.
登録日2010-12-22
公開日2011-09-07
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis for Antiviral Inhibition of the Main Protease, 3C, from Human Enterovirus 93.
J.Virol., 85, 2011
3Q3Y
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Complex structure of HEVB EV93 main protease 3C with Compound 1 (AG7404)
分子名称: 1,2-ETHANEDIOL, AMMONIUM ION, HEVB EV93 3C protease, ...
著者Costenaro, L, Kaczmarska, Z, Arnan, C, Sola, M, Coutard, B, Norder, H, Canard, B, Coll, M.
登録日2010-12-22
公開日2011-09-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献Structural Basis for Antiviral Inhibition of the Main Protease, 3C, from Human Enterovirus 93.
J.Virol., 85, 2011
3RUO
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Complex structure of HevB EV93 main protease 3C with Rupintrivir (AG7088)
分子名称: 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, CHLORIDE ION, HEVB EV93 3C PROTEASE, ...
著者Kaczmarska, Z, Janowski, R, Costenaro, L, Coutard, B, Norder, H, Canard, B, Coll, M.
登録日2011-05-05
公開日2011-09-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Basis for Antiviral Inhibition of the Main Protease, 3C, from Human Enterovirus 93.
J.Virol., 85, 2011
2J7W
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Dengue virus NS5 RNA dependent RNA polymerase domain complexed with 3' dGTP
分子名称: DI(HYDROXYETHYL)ETHER, GUANOSINE-5'-TRIPHOSPHATE, POLYPROTEIN, ...
著者Yap, T.L, Xu, T, Chen, Y.L, Malet, H, Egloff, M.P, Canard, B, Vasudevan, S.G, Lescar, J.
登録日2006-10-17
公開日2007-03-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution.
J.Virol., 81, 2007
2J7U
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Dengue virus NS5 RNA dependent RNA polymerase domain
分子名称: CHLORIDE ION, MAGNESIUM ION, RNA DEPENDENT RNA POLYMERASE, ...
著者Yap, T.L, Xu, T, Chen, Y.L, Malet, H, Egloff, M.P, Canard, B, Vasudevan, S.G, Lescar, J.
登録日2006-10-17
公開日2007-03-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution.
J.Virol., 81, 2007
2V6J
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Kokobera Virus Helicase: Mutant Met47Thr
分子名称: RNA HELICASE
著者Speroni, S, De Colibus, L, Coutard, B, Canard, B, Mattevi, A.
登録日2007-07-18
公開日2008-03-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and Biochemical Analysis of Kokobera Virus Helicase
Proteins: Struct., Funct., Bioinf., 70, 2008
2V6I
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Kokobera Virus Helicase
分子名称: PYROPHOSPHATE 2-, RNA HELICASE
著者Speroni, S, De Colibus, L, Coutard, B, Canard, B, Mattevi, A.
登録日2007-07-18
公開日2008-03-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and Biochemical Analysis of Kokobera Virus Helicase
Proteins: Struct., Funct., Bioinf., 70, 2008
2W5E
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Structural and biochemical analysis of human pathogenic astrovirus serine protease at 2.0 Angstrom resolution
分子名称: CADMIUM ION, CHLORIDE ION, PUTATIVE SERINE PROTEASE
著者Speroni, S, Rohayem, J, Nenci, S, Bonivento, D, Robel, I, Barthel, J, Coutard, B, Canard, B, Mattevi, A.
登録日2008-12-10
公開日2009-03-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and Biochemical Analysis of Human Pathogenic Astrovirus Serine Protease at 2.0 A Resolution.
J.Mol.Biol., 387, 2009
5LRP
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Mopeia Virus Exonuclease domain complexed with Magnesium
分子名称: MAGNESIUM ION, Nucleoprotein, ZINC ION
著者Yekwa, E.L, Khourieh, J, Canard, B, Ferron, F.
登録日2016-08-19
公開日2017-07-05
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.941 Å)
主引用文献Activity inhibition and crystal polymorphism induced by active-site metal swapping.
Acta Crystallogr D Struct Biol, 73, 2017

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