2PNA
 
 | | STRUCTURE OF AN SH2 DOMAIN OF THE P85 ALPHA SUBUNIT OF PHOSPHATIDYLINOSITOL-3-OH KINASE | | Descriptor: | PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT N-TERMINAL SH2 DOMAIN | | Authors: | Booker, G.W, Breeze, A.L, Downing, A.K, Panayotou, G, Gout, I, Waterfield, M.D, Campbell, I.D. | | Deposit date: | 1992-06-30 | | Release date: | 1994-01-31 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structure of an SH2 domain of the p85 alpha subunit of phosphatidylinositol-3-OH kinase.
Nature, 358, 1992
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1HKY
 | | Solution structure of a PAN module from Eimeria tenella | | Descriptor: | MICRONEME PROTEIN 5 PRECURSOR | | Authors: | Brown, P.J, Mulvey, D, Potts, J.R, Tomley, F.M, Campbell, I.D. | | Deposit date: | 2002-10-03 | | Release date: | 2002-10-17 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of a Pan Module from the Apicomplexan Parasite Eimeria Tenella
J.Struct.Funct.Genom., 4, 2003
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1QG9
 | | SECOND REPEAT (IS2MIC) FROM VOLTAGE-GATED SODIUM CHANNEL | | Descriptor: | PROTEIN (SODIUM CHANNEL PROTEIN, BRAIN II ALPHA SUBUNIT) | | Authors: | Doak, D.J, Mulvey, D, Kawaguchi, K, Villalain, J, Campbell, I.D. | | Deposit date: | 1999-04-22 | | Release date: | 1999-04-30 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Structural studies of synthetic peptides dissected from the voltage-gated sodium channel.
J.Mol.Biol., 258, 1996
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1QGB
 | | SOLUTION STRUCTURE OF THE N-TERMINAL F1 MODULE PAIR FROM HUMAN FIBRONECTIN | | Descriptor: | PROTEIN (FIBRONECTIN) | | Authors: | Potts, J.R, Bright, J.R, Bolton, D, Pickford, A.R, Campbell, I.D. | | Deposit date: | 1999-04-21 | | Release date: | 1999-12-08 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the N-terminal F1 module pair from human fibronectin.
Biochemistry, 38, 1999
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3TGF
 | | THE SOLUTION STRUCTURE OF HUMAN TRANSFORMING GROWTH FACTOR ALPHA | | Descriptor: | TRANSFORMING GROWTH FACTOR-ALPHA | | Authors: | Harvey, T.S, Wilkinson, A.J, Tappin, M.J, Cooke, R.M, Campbell, I.D. | | Deposit date: | 1991-01-23 | | Release date: | 1993-04-15 | | Last modified: | 2017-11-29 | | Method: | SOLUTION NMR | | Cite: | The solution structure of human transforming growth factor alpha.
Eur.J.Biochem., 198, 1991
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4HKC
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3MQL
 | | Crystal structure of the fibronectin 6FnI1-2FnII7FnI fragment | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Erat, M.C, Campbell, I.D, Vakonakis, I. | | Deposit date: | 2010-04-28 | | Release date: | 2010-08-25 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (3.004 Å) | | Cite: | Implications for collagen binding from the crystallographic structure of fibronectin 6FnI1-2FnII7FnI
J.Biol.Chem., 285, 2010
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3EJH
 | | Crystal Structure of the Fibronectin 8-9FnI Domain Pair in Complex with a Type-I Collagen Peptide | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Collagen type-I a1 chain, Fibronectin, ... | | Authors: | Erat, M.C, Lowe, E.D, Campbell, I.D, Vakonakis, I. | | Deposit date: | 2008-09-18 | | Release date: | 2009-02-03 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Identification and structural analysis of type I collagen sites in complex with fibronectin fragments.
Proc.Natl.Acad.Sci.USA, 106, 2009
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1A0N
 | | NMR STUDY OF THE SH3 DOMAIN FROM FYN PROTO-ONCOGENE TYROSINE KINASE COMPLEXED WITH THE SYNTHETIC PEPTIDE P2L CORRESPONDING TO RESIDUES 91-104 OF THE P85 SUBUNIT OF PI3-KINASE, FAMILY OF 25 STRUCTURES | | Descriptor: | FYN, PRO-PRO-ARG-PRO-LEU-PRO-VAL-ALA-PRO-GLY-SER-SER-LYS-THR | | Authors: | Renzoni, D.A, Pugh, D.J.R, Siligardi, G, Das, P, Morton, C.J, Rossi, C, Waterfield, M.D, Campbell, I.D, Ladbury, J.E. | | Deposit date: | 1997-12-05 | | Release date: | 1998-02-25 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structural and thermodynamic characterization of the interaction of the SH3 domain from Fyn with the proline-rich binding site on the p85 subunit of PI3-kinase.
Biochemistry, 35, 1996
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1AOU
 | | NMR STRUCTURE OF THE FYN SH2 DOMAIN COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE, 22 STRUCTURES | | Descriptor: | FYN PROTEIN-TYROSINE KINASE, PHOSPHOTYROSYL PEPTIDE | | Authors: | Mulhern, T.D, Shaw, G.L, Morton, C.J, Day, A.J, Campbell, I.D. | | Deposit date: | 1997-07-10 | | Release date: | 1998-01-14 | | Last modified: | 2021-11-03 | | Method: | SOLUTION NMR | | Cite: | The SH2 domain from the tyrosine kinase Fyn in complex with a phosphotyrosyl peptide reveals insights into domain stability and binding specificity.
Structure, 5, 1997
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1AZG
 | | NMR STUDY OF THE SH3 DOMAIN FROM FYN PROTO-ONCOGENE TYROSINE KINASE KINASE COMPLEXED WITH THE SYNTHETIC PEPTIDE P2L CORRESPONDING TO RESIDUES 91-104 OF THE P85 SUBUNIT OF PI3-KINASE, MINIMIZED AVERAGE (PROBMAP) STRUCTURE | | Descriptor: | FYN, PRO-PRO-ARG-PRO-LEU-PRO-VAL-ALA-PRO-GLY-SER-SER-LYS-THR | | Authors: | Renzoni, D.A, Pugh, D.J.R, Siligardi, G, Das, P, Morton, C.J, Rossi, C, Waterfield, M.D, Campbell, I.D, Ladbury, J.E. | | Deposit date: | 1997-11-18 | | Release date: | 1998-02-25 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structural and thermodynamic characterization of the interaction of the SH3 domain from Fyn with the proline-rich binding site on the p85 subunit of PI3-kinase.
Biochemistry, 35, 1996
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1AOT
 | | NMR STRUCTURE OF THE FYN SH2 DOMAIN COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE, MINIMIZED AVERAGE STRUCTURE | | Descriptor: | FYN PROTEIN-TYROSINE KINASE, PHOSPHOTYROSYL PEPTIDE | | Authors: | Mulhern, T.D, Shaw, G.L, Morton, C.J, Day, A.J, Campbell, I.D. | | Deposit date: | 1997-07-10 | | Release date: | 1998-01-14 | | Last modified: | 2024-10-23 | | Method: | SOLUTION NMR | | Cite: | The SH2 domain from the tyrosine kinase Fyn in complex with a phosphotyrosyl peptide reveals insights into domain stability and binding specificity.
Structure, 5, 1997
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1TTG
 | | THE THREE-DIMENSIONAL STRUCTURE OF THE TENTH TYPE III MODULE OF FIBRONECTIN: AN INSIGHT INTO RGD-MEDIATED INTERACTIONS | | Descriptor: | FIBRONECTIN | | Authors: | Main, A.L, Harvey, T.S, Baron, M, Campbell, I.D. | | Deposit date: | 1993-07-14 | | Release date: | 1994-01-31 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | The three-dimensional structure of the tenth type III module of fibronectin: an insight into RGD-mediated interactions.
Cell(Cambridge,Mass.), 71, 1992
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1TTF
 | | THE THREE-DIMENSIONAL STRUCTURE OF THE TENTH TYPE III MODULE OF FIBRONECTIN: AN INSIGHT INTO RGD-MEDIATED INTERACTIONS | | Descriptor: | FIBRONECTIN | | Authors: | Main, A.L, Harvey, T.S, Baron, M, Campbell, I.D. | | Deposit date: | 1993-07-14 | | Release date: | 1994-01-31 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | The three-dimensional structure of the tenth type III module of fibronectin: an insight into RGD-mediated interactions.
Cell(Cambridge,Mass.), 71, 1992
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1TPG
 | | F1-G MODULE PAIR RESIDUES 1-91 (C83S) OF TISSUE-TYPE PLASMINOGEN ACTIVATOR (T-PA) (NMR, 298K, PH2.95, REPRESENTATIVE STRUCTURE) | | Descriptor: | T-PLASMINOGEN ACTIVATOR F1-G | | Authors: | Smith, B.O, Downing, A.K, Driscoll, P.C, Dudgeon, T.J, Campbell, I.D. | | Deposit date: | 1995-06-14 | | Release date: | 1995-09-15 | | Last modified: | 2024-10-23 | | Method: | SOLUTION NMR | | Cite: | The solution structure and backbone dynamics of the fibronectin type I and epidermal growth factor-like pair of modules of tissue-type plasminogen activator.
Structure, 3, 1995
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3GXE
 | | Complex of a Low Affinity Collagen Site with the Fibronectin 8-9FnI Domain Pair | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Collagen alpha-1(I) chain, Fibronectin, ... | | Authors: | Sladek, B, Campbell, I.D, Vakonakis, I. | | Deposit date: | 2009-04-02 | | Release date: | 2010-04-07 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural analysis of collagen type I interactions with human fibronectin reveals a cooperative binding mode
J.Biol.Chem., 288, 2013
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3G9W
 | | Crystal Structure of Talin2 F2-F3 in Complex with the Integrin Beta1D Cytoplasmic Tail | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Integrin beta-1D, ... | | Authors: | Anthis, N.J, Wegener, K.L, Ye, F, Kim, C, Lowe, E.D, Vakonakis, I, Bate, N, Critchley, D.R, Ginsberg, M.H, Campbell, I.D. | | Deposit date: | 2009-02-15 | | Release date: | 2009-10-20 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.165 Å) | | Cite: | The structure of an integrin/talin complex reveals the basis of inside-out signal transduction
Embo J., 28, 2009
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3GF1
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1AUZ
 | | SOLUTION STRUCTURE OF SPOIIAA, A PHOSPHORYLATABLE COMPONENT OF THE SYSTEM THAT REGULATES TRANSCRIPTION FACTOR SIGMA-F OF BACILLUS SUBTILIS, NMR, 24 STRUCTURES | | Descriptor: | SPOIIAA | | Authors: | Kovacs, H, Comfort, D, Lord, M, Campbell, I.D, Yudkin, M.D. | | Deposit date: | 1997-09-08 | | Release date: | 1998-07-01 | | Last modified: | 2024-04-10 | | Method: | SOLUTION NMR | | Cite: | Solution structure of SpoIIAA, a phosphorylatable component of the system that regulates transcription factor sigmaF of Bacillus subtilis.
Proc.Natl.Acad.Sci.USA, 95, 1998
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2OII
 | | Structure of EMILIN-1 C1q-like domain | | Descriptor: | EMILIN-1 | | Authors: | Verdone, G, Colebrooke, S.A, Corazza, A, Cicero, D.O, Eliseo, T, Viglino, P, Campbell, I.D, Colombatti, A, Esposito, G. | | Deposit date: | 2007-01-11 | | Release date: | 2008-01-22 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | The solution structure of the C-terminal domain of EMILIN-1
To be Published
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1VVC
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1Y19
 | | Structural basis for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions | | Descriptor: | Phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma, Talin 1 | | Authors: | de Pereda, J.M, Wegener, K, Santelli, E, Bate, N, Ginsberg, M.H, Critchley, D.R, Campbell, I.D, Liddington, R.C. | | Deposit date: | 2004-11-17 | | Release date: | 2005-01-04 | | Last modified: | 2016-11-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural bases for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions
J.Biol.Chem., 280, 2005
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1BUZ
 | | SOLUTION STRUCTURE OF SPOIIAA, A PHOSPHORYLATABLE COMPONENT OF THE SYSTEM THAT REGULATES TRANSCRIPTION FACTOR SIGMA-F OF BACILLUS SUBTILIS NMR, MINIMIZED AVERAGE STRUCTURE | | Descriptor: | SPOIIAA | | Authors: | Kovacs, H, Comfort, D, Lord, M, Campbell, I.D, Yudkin, M.D. | | Deposit date: | 1997-09-08 | | Release date: | 1998-07-01 | | Last modified: | 2024-04-10 | | Method: | SOLUTION NMR | | Cite: | Solution structure of SpoIIAA, a phosphorylatable component of the system that regulates transcription factor sigmaF of Bacillus subtilis.
Proc.Natl.Acad.Sci.USA, 95, 1998
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1Z96
 | | Crystal structure of the Mud1 UBA domain | | Descriptor: | UBA-domain protein mud1 | | Authors: | Trempe, J.-F, Brown, N.R, Lowe, E.D, Noble, M.E.M, Gordon, C, Campbell, I.D, Johnson, L.N, Endicott, J.A. | | Deposit date: | 2005-03-31 | | Release date: | 2005-10-04 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Mechanism of Lys48-linked polyubiquitin chain recognition by the Mud1 UBA domain
Embo J., 24, 2005
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1HCC
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