5CA1
 
 | | Crystal structure of T2R-TTL-Nocodazole complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ... | | Authors: | Wang, Y, Yu, Y, Chen, Q, Yang, J. | | Deposit date: | 2015-06-29 | | Release date: | 2015-11-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.401 Å) | | Cite: | Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Febs J., 283, 2016
|
|
5CA0
 | | Crystal structure of T2R-TTL-Lexibulin complex | | Descriptor: | 1-ethyl-3-[2-methoxy-4-(5-methyl-4-{[(1S)-1-(pyridin-3-yl)butyl]amino}pyrimidin-2-yl)phenyl]urea, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | Authors: | Wang, Y, Yu, Y, Chen, Q, Yang, J. | | Deposit date: | 2015-06-29 | | Release date: | 2015-11-04 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.501 Å) | | Cite: | Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Febs J., 283, 2016
|
|
5CB4
 | | Crystal structure of T2R-TTL-Tivantinib complex | | Descriptor: | (3R,4R)-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | Authors: | Wang, Y, Yu, Y, Chen, Q, Yang, J. | | Deposit date: | 2015-06-30 | | Release date: | 2015-11-04 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.193 Å) | | Cite: | Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Febs J., 283, 2016
|
|
1NT2
 | | CRYSTAL STRUCTURE OF FIBRILLARIN/NOP5P COMPLEX | | Descriptor: | Fibrillarin-like pre-rRNA processing protein, S-ADENOSYLMETHIONINE, conserved hypothetical protein | | Authors: | Aittaleb, M, Rashid, R, Chen, Q, Palmer, J.R, Daniels, C.J, Li, H. | | Deposit date: | 2003-01-28 | | Release date: | 2003-04-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structure and function of archaeal box C/D sRNP core proteins.
Nat.Struct.Biol., 10, 2003
|
|
5BMV
 | | CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-Vinblastine COMPLEX | | Descriptor: | (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | Authors: | Wang, Y, Chen, Q, Zhang, R. | | Deposit date: | 2015-05-23 | | Release date: | 2016-07-13 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules.
Mol.Pharmacol., 89, 2016
|
|
5GT9
 | | The X-ray structure of 7beta-hydroxysteroid dehydrogenase | | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase, short chain dehydrogenase/reductase family protein | | Authors: | Wang, F, Wang, R, Lv, Z, Chen, Q, Huo, X. | | Deposit date: | 2016-08-19 | | Release date: | 2017-05-17 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure of NADP(+)-bound 7 beta-hydroxysteroid dehydrogenase reveals two cofactor-binding modes
Acta Crystallogr F Struct Biol Commun, 73, 2017
|
|
7RPM
 | |
5E1J
 | | Structure of voltage-gated two-pore channel TPC1 from Arabidopsis thaliana | | Descriptor: | BARIUM ION, CALCIUM ION, Two pore calcium channel protein 1 | | Authors: | Guo, J, Zeng, W, Chen, Q, Lee, C, Chen, L, Yang, Y, Jiang, Y. | | Deposit date: | 2015-09-29 | | Release date: | 2015-12-16 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (3.308 Å) | | Cite: | Structure of the voltage-gated two-pore channel TPC1 from Arabidopsis thaliana.
Nature, 531, 2016
|
|
4B02
 | | The C-terminal Priming Domain is Strongly Associated with the Main Body of Bacteriophage phi6 RNA-Dependent RNA Polymerase | | Descriptor: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | | Authors: | Sarin, L.P, Wright, S, Chen, Q, Degerth, L.H, Stuart, D.I, Grimes, J.M, Bamford, D.H, Poranen, M.M. | | Deposit date: | 2012-06-27 | | Release date: | 2012-08-01 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | The C-Terminal Priming Domain is Strongly Associated with the Main Body of Bacteriophage Phi6 RNA-Dependent RNA Polymerase.
Virology, 432, 2012
|
|
6EC3
 | | Crystal Structure of EvdMO1 | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Methyltransferase domain-containing protein, NICKEL (II) ION | | Authors: | McCulloch, K.M, Iverson, T.M, Starbird, C.A, Perry, N.A, Chen, Q, Berndt, S, Yamakawa, I, Loukachevitch, L.V. | | Deposit date: | 2018-08-07 | | Release date: | 2018-12-26 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | The Structure of the Bifunctional Everninomicin Biosynthetic Enzyme EvdMO1 Suggests Independent Activity of the Fused Methyltransferase-Oxidase Domains.
Biochemistry, 57, 2018
|
|
5EZY
 | | Crystal structure of T2R-TTL-taccalonolide AJ complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Wang, Y, Yu, Y, Chen, Q, Yang, J. | | Deposit date: | 2015-11-27 | | Release date: | 2017-01-11 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Mechanism of microtubule stabilization by taccalonolide AJ
Nat Commun, 8, 2017
|
|
4XBS
 | | 2-deoxyribose-5-phosphate aldolase mutant - E78K | | Descriptor: | Deoxyribose-phosphate aldolase | | Authors: | Jiao, X.-C, Pan, J, Xu, G.-C, Kong, X.-D, Chen, Q, Zhang, Z.-J, Xu, J.-H. | | Deposit date: | 2014-12-17 | | Release date: | 2015-11-04 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Efficient synthesis of a statin precursor in high space-time yield by a new aldehyde-tolerant aldolase identified from Lactobacillus brevis
Catalysis Science And Technology, 5, 2015
|
|
4XBK
 | | 2-deoxyribose-5-phosphate aldolase from Lactobacillus brevis | | Descriptor: | ACETIC ACID, Deoxyribose-phosphate aldolase | | Authors: | Jiao, X.-C, Pan, J, Xu, G.-C, Kong, X.-D, Chen, Q, Zhang, Z.-J, Xu, J.-H. | | Deposit date: | 2014-12-17 | | Release date: | 2015-11-04 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.951 Å) | | Cite: | Efficient synthesis of a statin precursor in high space-time yield by a new aldehyde-tolerant aldolase identified from Lactobacillus brevis
Catalysis Science And Technology, 5, 2015
|
|
4E26
 | | BRAF in complex with an organic inhibitor 7898734 | | Descriptor: | 5-chloro-7-[(R)-furan-2-yl(pyridin-2-ylamino)methyl]quinolin-8-ol, Serine/threonine-protein kinase B-raf | | Authors: | Qin, J, Xie, P, Ventocilla, C, Zhou, G, Vultur, A, Chen, Q, Herlyn, M, Winkler, J, Marmorstein, R. | | Deposit date: | 2012-03-07 | | Release date: | 2012-05-09 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Identification of a Novel Family of BRAF(V600E) Inhibitors.
J.Med.Chem., 55, 2012
|
|
4J0I
 | | Tannin acyl hydrolase in complex with 3,4-dihydroxybenzoate | | Descriptor: | 3,4-DIHYDROXYBENZOIC ACID, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, ... | | Authors: | Ren, B, Wu, M, Wang, Q, Peng, X, Wen, H, Chen, Q, McKinstry, W.J. | | Deposit date: | 2013-01-30 | | Release date: | 2013-05-22 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystal structure of tannase from Lactobacillus plantarum.
J.Mol.Biol., 425, 2013
|
|
4J0J
 | | Tannin acyl hydrolase in complex with ethyl 3,5-dihydroxybenzoate | | Descriptor: | Tannase, ethyl 3,5-dihydroxybenzoate | | Authors: | Ren, B, Wu, M, Wang, Q, Peng, X, Wen, H, Chen, Q, McKinstry, W.J. | | Deposit date: | 2013-01-31 | | Release date: | 2013-05-22 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of tannase from Lactobacillus plantarum.
J.Mol.Biol., 425, 2013
|
|
4J0G
 | | Tannin acyl hydrolase (mercury derivative) | | Descriptor: | DI(HYDROXYETHYL)ETHER, MERCURY (II) ION, PENTAETHYLENE GLYCOL, ... | | Authors: | Ren, B, Wu, M, Wang, Q, Peng, X, Wen, H, Chen, Q, McKinstry, W.J. | | Deposit date: | 2013-01-30 | | Release date: | 2013-05-22 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of tannase from Lactobacillus plantarum.
J.Mol.Biol., 425, 2013
|
|
4J0C
 | | tannin acyl hydrolase from Lactobacillus plantarum (native structure) | | Descriptor: | DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, Tannase | | Authors: | Wu, M, Wang, Q, Peng, X, Wen, H, Chen, Q, McKinstry, W.J. | | Deposit date: | 2013-01-30 | | Release date: | 2013-05-22 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Crystal structure of tannase from Lactobacillus plantarum.
J.Mol.Biol., 425, 2013
|
|
4J0K
 | | Tannin acyl hydrolase in complex with ethyl gallate | | Descriptor: | DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ... | | Authors: | Ren, B, Wu, M, Wang, Q, Peng, X, Wen, H, Chen, Q, McKinstry, W.J. | | Deposit date: | 2013-01-31 | | Release date: | 2013-05-22 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Crystal structure of tannase from Lactobacillus plantarum.
J.Mol.Biol., 425, 2013
|
|
4J0D
 | | tannin acyl hydrolase from Lactobacillus plantarum (Cadmium) | | Descriptor: | CADMIUM ION, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, ... | | Authors: | Ren, B, Wu, M, Wang, Q, Peng, X, Wen, H, Chen, Q, McKinstry, W.J. | | Deposit date: | 2013-01-30 | | Release date: | 2013-05-22 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structure of tannase from Lactobacillus plantarum.
J.Mol.Biol., 425, 2013
|
|
4J0H
 | | Tannin acyl hydrolase in complex with gallic acid | | Descriptor: | 3,4,5-trihydroxybenzoic acid, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, ... | | Authors: | Ren, B, Wu, M, Wang, Q, Peng, X, Wen, H, Chen, Q, McKinstry, W.J. | | Deposit date: | 2013-01-30 | | Release date: | 2013-05-22 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of tannase from Lactobacillus plantarum.
J.Mol.Biol., 425, 2013
|
|
4JUI
 | | crystal structure of tannase from from Lactobacillus plantarum | | Descriptor: | DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ... | | Authors: | Ren, B, Wu, M, Wang, Q, Peng, X, Wen, H, McKinstry, W.J, Chen, Q. | | Deposit date: | 2013-03-24 | | Release date: | 2013-05-22 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of tannase from Lactobacillus plantarum.
J.Mol.Biol., 425, 2013
|
|
2MLB
 | | NMR solution structure of a computational designed protein based on template of human erythrocytic ubiquitin | | Descriptor: | redesigned ubiquitin | | Authors: | Xiong, P, Wang, M, Zhang, J, Chen, Q, Liu, H. | | Deposit date: | 2014-02-21 | | Release date: | 2014-10-29 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Protein design with a comprehensive statistical energy function and boosted by experimental selection for foldability
Nat Commun, 5, 2014
|
|
2MN4
 | | NMR solution structure of a computational designed protein based on structure template 1cy5 | | Descriptor: | Computational designed protein based on structure template 1cy5 | | Authors: | Xiong, P, Wang, M, Zhang, J, Chen, Q, Liu, H. | | Deposit date: | 2014-03-28 | | Release date: | 2014-10-29 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Protein design with a comprehensive statistical energy function and boosted by experimental selection for foldability
Nat Commun, 5, 2014
|
|
7V6J
 | | LcCOMT in complex with SAM | | Descriptor: | LcCOMT, S-ADENOSYLMETHIONINE, SODIUM ION | | Authors: | Yu, Y, CHen, Q. | | Deposit date: | 2021-08-20 | | Release date: | 2021-12-29 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.799 Å) | | Cite: | Structure basis of the caffeic acid O-methyltransferase from Ligusiticum chuanxiong to understand its selective mechanism.
Int.J.Biol.Macromol., 194, 2022
|
|
