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PDB: 1279 件
4W60
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The structure of Vaccina virus H7 protein displays A Novel Phosphoinositide binding fold required for membrane biogenesis
分子名称: Late protein H7
著者Kolli, S, Meng, X, Wu, X, Shengjuler, D, Cameron, C.E, Xiang, Y, Deng, J.
登録日2014-08-19
公開日2014-12-31
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure-function analysis of vaccinia virus h7 protein reveals a novel phosphoinositide binding fold essential for poxvirus replication.
J.Virol., 89, 2015
4V97
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BU of 4v97 by Molmil
Crystal structure of the bacterial ribosome ram mutation G299A.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fagan, C.E, Dunkle, J.A, Maehigashi, T, Dunham, C.M.
登録日2012-04-06
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.516 Å)
主引用文献Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state.
Proc.Natl.Acad.Sci.USA, 110, 2013
3G3Z
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BU of 3g3z by Molmil
The structure of NMB1585, a MarR family regulator from Neisseria meningitidis
分子名称: Transcriptional regulator, MarR family
著者Nichols, C.E, Sainsbury, S, Ren, J, Walter, T.S, Verma, A, Stammers, D.K, Saunders, N.J, Owens, R.J, Oxford Protein Production Facility (OPPF)
登録日2009-02-03
公開日2009-04-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structure of NMB1585, a MarR-family regulator from Neisseria meningitidis
Acta Crystallogr.,Sect.F, 65, 2009
3G06
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BU of 3g06 by Molmil
The Salmonella Virulence Effector SspH2 Functions As A Novel E3 Ligase
分子名称: SspH2 (Leucine-rich repeat protein)
著者Quezada, C.M, Stebbins, C.E.
登録日2009-01-27
公開日2009-04-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A family of Salmonella virulence factors functions as a distinct class of autoregulated E3 ubiquitin ligases.
Proc.Natl.Acad.Sci.USA, 106, 2009
3ET9
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BU of 3et9 by Molmil
Crystal structure of the engineered neutralizing antibody 1H
分子名称: Antibody 1H light chain and antibody 1H heavy chain linked with a synthetic (GGGGS)4 linker
著者Leysath, C.E, Monzingo, A.F, Barnett, J, Iverson, B.L, Georgiou, G, Robertus, J.D.
登録日2008-10-07
公開日2009-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the engineered neutralizing antibody m18 complexed to domain 4 of the anthrax protective antigen.
J.Mol.Biol., 387, 2009
3ESV
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BU of 3esv by Molmil
Crystal structure of the engineered neutralizing antibody M18
分子名称: Antibody M18 light chain and antibody M18 heavy chain linked with a synthetic (GGGGS)4 linker
著者Monzingo, A.F, Leysath, C.E, Barnett, J, Iverson, B.L, Georgiou, G, Robertus, J.D.
登録日2008-10-06
公開日2009-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the engineered neutralizing antibody m18 complexed to domain 4 of the anthrax protective antigen.
J.Mol.Biol., 387, 2009
3H4R
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BU of 3h4r by Molmil
Crystal structure of E. coli RecE exonuclease
分子名称: Exodeoxyribonuclease 8
著者Bell, C.E, Zhang, J.
登録日2009-04-20
公開日2009-05-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of E. coli RecE protein reveals a toroidal tetramer for processing double-stranded DNA breaks.
Structure, 17, 2009
3HD4
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BU of 3hd4 by Molmil
MHV Nucleocapsid Protein NTD
分子名称: Nucleoprotein
著者Giedroc, D.P, Keane, S.C, Dann III, C.E.
登録日2009-05-06
公開日2009-11-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.747 Å)
主引用文献Coronavirus N Protein N-Terminal Domain (NTD) Specifically Binds the Transcriptional Regulatory Sequence (TRS) and Melts TRS-cTRS RNA Duplexes.
J.Mol.Biol., 394, 2009
4ZYY
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BU of 4zyy by Molmil
Human GAR transformylase in complex with GAR and (S)-2-({5-[4-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]-pyrimidin-6-yl)butyl]thiophene-3-carbonyl}amino)pentanedioic acid (AGF118)
分子名称: (S)-2-({5-[4-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]-pyrimidin-6-yl)butyl]thiophene-3-carbonyl}amino)pentanedioic acid, GLYCINAMIDE RIBONUCLEOTIDE, Trifunctional purine biosynthetic protein adenosine-3
著者Deis, S.M, Dann III, C.E.
登録日2015-05-22
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase.
Biochemistry, 55, 2016
4ZZ3
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Human GAR transformylase in complex with GAR and pemetrexed
分子名称: GLYCINAMIDE RIBONUCLEOTIDE, N-{4-[2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid, Trifunctional purine biosynthetic protein adenosine-3
著者Deis, S.M, Dann III, C.E.
登録日2015-05-22
公開日2015-12-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.504 Å)
主引用文献6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor alpha and the Proton-Coupled Folate Transporter in Human Tumors.
J.Med.Chem., 58, 2015
2FYR
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BU of 2fyr by Molmil
Crystal Structure of Norwalk Virus Protease grown in the presence of AEBSF
分子名称: CHLORIDE ION, Chymotrypsin-like cysteine proteinase, MAGNESIUM ION
著者Zeitler, C.E, Estes, M.K, Venkataram Prasad, B.V.
登録日2006-02-08
公開日2006-07-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献X-ray crystallographic structure of the Norwalk virus protease at 1.5-A resolution.
J.Virol., 80, 2006
2GHD
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Conformational mobility in the active site of a heme peroxidase
分子名称: CYANIDE ION, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ...
著者Badyal, S.K, Joyce, M.G, Sharp, K.H, Raven, E.L, Moody, P.C.E.
登録日2006-03-27
公開日2006-06-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Conformational Mobility in the Active Site of a Heme Peroxidase.
J.Biol.Chem., 281, 2006
4ZZ0
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BU of 4zz0 by Molmil
Human GAR transformylase in complex with GAR and (S)-2-(8-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)octanamido)pentanedioic acid (AGF147)
分子名称: (S)-2-(8-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)octanamido)pentanedioic acid, GLYCINAMIDE RIBONUCLEOTIDE, Trifunctional purine biosynthetic protein adenosine-3
著者Deis, S.M, Dann III, C.E.
登録日2015-05-22
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase.
Biochemistry, 55, 2016
4ZYX
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BU of 4zyx by Molmil
Human GAR transformylase in complex with GAR and (S)-2-({4-[4-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]-pyrimidin-6-yl)butyl]thiophene-2-carbonyl}amino)pentanedioic acid (AGF117)
分子名称: GLYCINAMIDE RIBONUCLEOTIDE, N-({4-[4-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)butyl]thiophen-2-yl}carbonyl)-L-glutamic acid, Trifunctional purine biosynthetic protein adenosine-3
著者Deis, S.M, Dann III, C.E.
登録日2015-05-22
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase.
Biochemistry, 55, 2016
4PXZ
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BU of 4pxz by Molmil
Crystal structure of P2Y12 receptor in complex with 2MeSADP
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate), CHOLESTEROL, ...
著者Zhang, J, Zhang, K, Gao, Z.G, Paoletta, S, Zhang, D, Han, G.W, Li, T, Ma, L, Zhang, W, Muller, C.E, Yang, H, Jiang, H, Cherezov, V, Katritch, V, Jacobson, K.A, Stevens, R.C, Wu, B, Zhao, Q, GPCR Network (GPCR)
登録日2014-03-25
公開日2014-04-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Agonist-bound structure of the human P2Y12 receptor
Nature, 509, 2014
4ZYV
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BU of 4zyv by Molmil
Human GAR transformylase in complex with GAR and N-({5-[(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)butyl]thiophen-2-yl}carbonyl)-L-glutamic acid (AGF71)
分子名称: GLYCINAMIDE RIBONUCLEOTIDE, N-({5-[4-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-6-yl)butyl]thiophen-2-yl}carbonyl)-L-glutamic acid, Trifunctional purine biosynthetic protein adenosine-3
著者Deis, S.M, Dann III, C.E.
登録日2015-05-22
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.053 Å)
主引用文献Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase.
Biochemistry, 55, 2016
4ZZ2
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BU of 4zz2 by Molmil
HUMAN GAR TRANSFORMYLASE IN COMPLEX WITH GAR AND (S)-2-({5-[3-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-6-YL)-PROPYL]-THIOPHENE-3-CARBONYL}-AMINO)-PENTANEDIOIC ACID
分子名称: (S)-2-({5-[3-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)-propyl]-thiophene-3-carbonyl}-amino)-pentanedioic acid, GLYCINAMIDE RIBONUCLEOTIDE, Trifunctional purine biosynthetic protein adenosine-3
著者Deis, S.M, Dann III, C.E.
登録日2015-05-22
公開日2015-12-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor alpha and the Proton-Coupled Folate Transporter in Human Tumors.
J.Med.Chem., 58, 2015
2GGN
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Conformational mobility in the active site of a heme peroxidase
分子名称: PROTOPORPHYRIN IX CONTAINING FE, SODIUM ION, SULFATE ION, ...
著者Badyal, S.K, Joyce, M.G, Sharp, K.H, Raven, E.L, Moody, P.C.E.
登録日2006-03-24
公開日2006-06-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Conformational Mobility in the Active Site of a Heme Peroxidase.
J.Biol.Chem., 281, 2006
2FYQ
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BU of 2fyq by Molmil
Crystal Structure of the Norwalk Virus Protease
分子名称: CHLORIDE ION, Chymotrypsin-like cysteine proteinase, PHOSPHATE ION
著者Zeitler, C.E, Estes, M.K, Venkataram Prasad, B.V.
登録日2006-02-08
公開日2006-07-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献X-ray crystallographic structure of the Norwalk virus protease at 1.5-A resolution.
J.Virol., 80, 2006
2GHK
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BU of 2ghk by Molmil
Conformational mobility in the active site of a heme peroxidase
分子名称: CYANIDE ION, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Badyal, S.K, Joyce, M.G, Sharp, K.H, Raven, E.L, Moody, P.C.E.
登録日2006-03-27
公開日2006-06-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Conformational Mobility in the Active Site of a Heme Peroxidase.
J.Biol.Chem., 281, 2006
4ZYU
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BU of 4zyu by Molmil
Human GAR transformylase in complex with GAR and N-{4-[4-(2-Amino-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-6-yl)-butyl]benzoyl}-L-glutamic acid (AGF50)
分子名称: GLYCINAMIDE RIBONUCLEOTIDE, N-{4-[4-(2-amino-4-oxo-1,4-dihydrothieno[2,3-d]pyrimidin-6-yl)butyl]benzoyl}-L-glutamic acid, Trifunctional purine biosynthetic protein adenosine-3
著者Deis, S.M, Dann III, C.E.
登録日2015-05-22
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase.
Biochemistry, 55, 2016
2GEM
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BU of 2gem by Molmil
2.1A crystal structure of Salmonella tyhpimurium YeaZ, a putative Gram-negative RPF, form-A
分子名称: Putative Gram negative resuscitation promoting factor
著者Nichols, C.E, Stammers, D.K.
登録日2006-03-20
公開日2006-08-01
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Characterization of Salmonella typhimurium YeaZ, an M22 O-Sialoglycoprotein Endopeptidase Homolog
Proteins, 64, 2006
4ZRT
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BU of 4zrt by Molmil
PTP1BC215S bound to Nephrin peptide substrate
分子名称: CHLORIDE ION, GLY-PRO-LEU-PTR-ASP-GLU, GLYCEROL, ...
著者Selner, N.G, Bell, C.E, Pei, D.
登録日2015-05-12
公開日2015-06-24
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Diverse levels of sequence selectivity and catalytic efficiency of protein-tyrosine phosphatases.
Biochemistry, 53, 2014
4ZZ1
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BU of 4zz1 by Molmil
HUMAN GAR TRANSFORMYLASE IN COMPLEX WITH GAR AND (S)-2-({4-[3-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-6-YL)-PROPYL]-THIOPHENE-2-CARBONYL}-AMINO)-PENTANEDIOIC ACID
分子名称: (S)-2-({4-[3-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)-propyl]-thiophene-2-carbonyl}-amino)-pentanedioic acid, GLYCINAMIDE RIBONUCLEOTIDE, Trifunctional purine biosynthetic protein adenosine-3
著者Deis, S.M, Dann III, C.E.
登録日2015-05-22
公開日2015-12-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.351 Å)
主引用文献6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor alpha and the Proton-Coupled Folate Transporter in Human Tumors.
J.Med.Chem., 58, 2015
5A6R
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BU of 5a6r by Molmil
Crystal structure of the BTB domain of human KCTD17
分子名称: BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD17
著者Pinkas, D.M, Sorrell, F, Sanvitale, C.E, Goubin, S, Williams, E, Newman, J.A, Pearce, N.M, Neshich, I, Pike, A.C.W, MacKenzie, A, Quigley, A, Faust, B, Carpenter, E.P, Tallant, C, Kopec, J, Chalk, R, Krojer, T, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.
登録日2015-06-30
公開日2015-11-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural complexity in the KCTD family of Cullin3-dependent E3 ubiquitin ligases.
Biochem. J., 474, 2017

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