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PDB: 2660 件

4HX6
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Streptomyces globisporus C-1027 NADH:FAD oxidoreductase SgcE6
分子名称: ACETATE ION, Oxidoreductase, SULFATE ION
著者Tan, K, Bigelow, L, Clancy, S, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2012-11-09
公開日2012-11-28
最終更新日2016-12-07
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus.
Biochemistry, 55, 2016
1MBZ
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BETA-LACTAM SYNTHETASE WITH TRAPPED INTERMEDIATE
分子名称: ARGININE-N-METHYLCARBONYL PHOSPHORIC ACID 5'-ADENOSINE ESTER, BETA-LACTAM SYNTHETASE, GLYCEROL, ...
著者Miller, M.T, Bachmann, B.O, Townsend, C.A, Rosenzweig, A.C.
登録日2002-08-04
公開日2002-10-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献The catalytic cycle of beta -lactam synthetase observed by x-ray crystallographic snapshots
Proc.Natl.Acad.Sci.USA, 99, 2002
4HPL
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PCGF1 Ub fold (RAWUL)/BCOR PUFD Complex
分子名称: BCL-6 corepressor, Polycomb group RING finger protein 1
著者Junco, S.E, Wang, R, Gaipa, J, Taylor, A.B, Gearhart, M.D, Bardwell, V.J, Hart, P.J, Kim, C.A.
登録日2012-10-24
公開日2013-05-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the Polycomb Group Protein PCGF1 in Complex with BCOR Reveals Basis for Binding Selectivity of PCGF Homologs.
Structure, 21, 2013
4HT5
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CO2 concentrating mechanism protein P, CcmP form 1
分子名称: CO2 concentrating mechanism protein P
著者Cai, F, Sutter, M, Kerfeld, C.A.
登録日2012-10-31
公開日2013-04-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献The structure of CcmP, a tandem bacterial microcompartment domain protein from the beta-carboxysome, forms a subcompartment within a microcompartment.
J.Biol.Chem., 288, 2013
1MG7
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Crystal Structure of xol-1
分子名称: early switch protein xol-1 2.2k splice form
著者Luz, J.G, Hassig, C.A, Godzik, A, Meyer, B.J, Wilson, I.A.
登録日2002-08-14
公開日2003-04-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators
Genes Dev., 17, 2003
4HVM
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Crystal structure of tallysomycin biosynthesis protein TlmII
分子名称: SULFATE ION, TlmII
著者Chang, C, Bigelow, L, Bearden, J, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2012-11-06
公開日2012-11-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.704 Å)
主引用文献Crystal structure of tallysomycin biosynthesis protein TlmII
To be Published
4HZP
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The Structure of the Bifunctional Acetyltransferase/Decarboxylase LnmK from the Leinamycin Biosynthetic Pathway Revealing Novel Activity for a Double Hot Dog Fold
分子名称: Bifunctional methylmalonyl-CoA:ACP Acyltransferase/Decarboxylase, CHLORIDE ION, COENZYME A, ...
著者Lohman, J.R, Bingman, C.A, Phillips Jr, G.N, Shen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2012-11-15
公開日2013-01-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structure of the Bifunctional Acyltransferase/Decarboxylase LnmK from the Leinamycin Biosynthetic Pathway Revealing Novel Activity for a Double-Hot-Dog Fold.
Biochemistry, 52, 2013
2OZA
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Structure of p38alpha complex
分子名称: MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase 14
著者White, A, Pargellis, C.A, Studts, J.M, Werneburg, B.G, Farmer II, B.T.
登録日2007-02-25
公開日2007-04-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular basis of MAPK-activated protein kinase 2:p38 assembly
Proc.Natl.Acad.Sci.Usa, 104, 2007
2GRM
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Crystal structure of PrgX/iCF10 complex
分子名称: PrgX, peptide
著者Shi, K, Kozlowicz, B.K, Gu, Z.Y, Ohlendorf, D.H, Earhart, C.A, Dunny, G.M.
登録日2006-04-24
公開日2007-04-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular basis for control of conjugation by bacterial pheromone and inhibitor peptides.
Mol.Microbiol., 62, 2006
4HZN
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The Structure of the Bifunctional Acetyltransferase/Decarboxylase LnmK from the Leinamycin Biosynthetic Pathway Revealing Novel Activity for a Double Hot Dog Fold
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bifunctional Methylmalonyl-CoA:ACP Acyltransferase/Decarboxylase, GLYCEROL, ...
著者Lohman, J.R, Bingman, C.A, Phillips Jr, G.N, Shen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2012-11-15
公開日2013-01-30
最終更新日2013-02-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure of the Bifunctional Acyltransferase/Decarboxylase LnmK from the Leinamycin Biosynthetic Pathway Revealing Novel Activity for a Double-Hot-Dog Fold.
Biochemistry, 52, 2013
3TYV
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SAR development and discovery of potent indole-based inhibitors of the hepatitis C virus NS5B polymerase
分子名称: N-(cyclopropylsulfonyl)-1-(2,5-difluorobenzyl)-6-fluoro-5-methyl-3-(2-oxo-1,2-dihydropyridin-3-yl)-1H-indole-2-carboxamide, PHOSPHATE ION, RNA-directed RNA polymerase
著者Lesburg, C.A, Chen, K.X.
登録日2011-09-26
公開日2012-02-01
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure-Activity Relationship (SAR) Development and Discovery of Potent Indole-Based Inhibitors of the Hepatitis C Virus (HCV) NS5B Polymerase.
J.Med.Chem., 55, 2012
3U64
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The Crystal Structure of Tat-T (Tp0956)
分子名称: Protein TP_0956, SULFATE ION
著者Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V.
登録日2011-10-12
公開日2012-02-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural, Bioinformatic, and In Vivo Analyses of Two Treponema pallidum Lipoproteins Reveal a Unique TRAP Transporter.
J.Mol.Biol., 416, 2012
2GNX
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X-ray structure of a hypothetical protein from Mouse Mm.209172
分子名称: hypothetical protein
著者Phillips Jr, G.N, McCoy, J.G, Bitto, E, Wesenberg, G.E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
登録日2006-04-11
公開日2006-05-02
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献X-ray structure of a hypothetical protein from Mouse Mm.209172
To be Published
2MBQ
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K11-linked Diubiquitin average solution structure at pH 6.8, 150 mM NaCl
分子名称: Ubiquitin
著者Castaneda, C.A, Fushman, D.
登録日2013-08-03
公開日2013-09-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Unique structural, dynamical, and functional properties of k11-linked polyubiquitin chains.
Structure, 21, 2013
2GO3
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BU of 2go3 by Molmil
Crystal structure of Aquifex aeolicus LpxC complexed with imidazole.
分子名称: CHLORIDE ION, GLYCEROL, IMIDAZOLE, ...
著者Gennadios, H.A, Whittington, D.A, Li, X, Fierke, C.A, Christianson, D.W.
登録日2006-04-12
公開日2006-07-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanistic Inferences from the Binding of Ligands to LpxC, a Metal-Dependent Deacetylase
Biochemistry, 45, 2006
2MBO
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K11-linked Diubiquitin average solution structure at pH 6.8, 0 mM NaCl
分子名称: Ubiquitin
著者Castaneda, C.A, Fushman, D.
登録日2013-08-02
公開日2013-09-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Unique structural, dynamical, and functional properties of k11-linked polyubiquitin chains.
Structure, 21, 2013
4HZO
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BU of 4hzo by Molmil
The Structure of the Bifunctional Acetyltransferase/Decarboxylase LnmK from the Leinamycin Biosynthetic Pathway Revealing Novel Activity for a Double Hot Dog Fold
分子名称: Bifunctional methylmalonyl-CoA:ACP acyltransferase/decarboxylase, CHLORIDE ION, COENZYME A
著者Lohman, J.R, Bingman, C.A, Phillips Jr, G.N, Shen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2012-11-15
公開日2013-01-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structure of the Bifunctional Acyltransferase/Decarboxylase LnmK from the Leinamycin Biosynthetic Pathway Revealing Novel Activity for a Double-Hot-Dog Fold.
Biochemistry, 52, 2013
2LZZ
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Solution structure of a mutant of the triheme cytochrome PpcA from Geobacter sulfurreducens sheds light on the role of the conserved aromatic residue F15
分子名称: Cytochrome c, 3 heme-binding sites, PROTOPORPHYRIN IX CONTAINING FE
著者Dantas, J.M, Morgado, L, Turner, D.L, Salgueiro, C.A.
登録日2012-10-12
公開日2013-01-30
最終更新日2024-10-16
実験手法SOLUTION NMR
主引用文献Solution structure of a mutant of the triheme cytochrome PpcA from Geobacter sulfurreducens sheds light on the role of the conserved aromatic residue F15.
Biochim.Biophys.Acta, 1827, 2013
2MFY
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Non-reducible analogues of alpha-conotoxin Vc1.1: [2,8]-trans dicarba Vc1.1
分子名称: Alpha-conotoxin Vc1A
著者Robinson, S.D, Macraild, C.A, Van Lierop, B.J, Robinson, A.J, Norton, R.S.
登録日2013-10-24
公開日2013-12-18
実験手法SOLUTION NMR
主引用文献Dicarba alpha-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors.
Acs Chem.Biol., 8, 2013
4I19
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The crystal structure of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus.
分子名称: ACETATE ION, Epoxide hydrolase, FORMIC ACID
著者Tan, K, Bigelow, L, Clancy, S, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2012-11-20
公開日2012-12-05
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.148 Å)
主引用文献The crystal structure of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus.
To be Published
2PC4
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Crystal structure of fructose-bisphosphate aldolase from Plasmodium falciparum in complex with TRAP-tail determined at 2.4 angstrom resolution
分子名称: Fructose-bisphosphate aldolase, PbTRAP
著者Bosch, J, Buscaglia, C.A, Krumm, B, Cardozo, T, Nussenzweig, V, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2007-03-29
公開日2007-04-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Aldolase provides an unusual binding site for thrombospondin-related anonymous protein in the invasion machinery of the malaria parasite.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3ZDG
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Crystal Structure of Ls-AChBP complexed with carbamoylcholine analogue 3-(dimethylamino)butyl dimethylcarbamate (DMABC)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(dimethylamino)butyl dimethylcarbamate, ACETYLCHOLINE BINDING PROTEIN, ...
著者Ussing, C.A, Hansen, C.P, Petersen, J.G, Jensen, A.A, Rohde, L.A.H, Ahring, P.K, Nielsen, E.O, Kastrup, J.S, Gajhede, M, Frolund, B, Balle, T.
登録日2012-11-26
公開日2013-02-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Synthesis, Pharmacology, and Biostructural Characterization of Novel Alpha(4)Beta(2) Nicotinic Acetylcholine Receptor Agonists.
J.Med.Chem., 56, 2013
3ZDH
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Crystal structure of Ls-AChBP complexed with carbamoylcholine analogue N,N-dimethyl-4-(1-methyl-1H-imidazol-2-yloxy)butan-2-amine
分子名称: (2R)-N,N-dimethyl-4-(1-methylimidazol-2-yl)oxy-butan-2-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINE BINDING PROTEIN, ...
著者Ussing, C.A, Hansen, C.P, Petersen, J.G, Jensen, A.A, Rohde, L.A.H, Ahring, P.K, Nielsen, E.O, Kastrup, J.S, Gajhede, M, Frolund, B, Balle, T.
登録日2012-11-26
公開日2013-02-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.195 Å)
主引用文献Synthesis, Pharmacology, and Biostructural Characterization of Novel Alpha(4)Beta(2) Nicotinic Acetylcholine Receptor Agonists.
J.Med.Chem., 56, 2013
2K9E
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BU of 2k9e by Molmil
NMR Solution Structure for ShK-192: A Potent KV1.3-Specific Immunosuppressive Polypeptide
分子名称: Kappa-stichotoxin-She3a
著者Galea, C.A.
登録日2008-10-09
公開日2009-01-20
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Engineering a stable and selective peptide blocker of the Kv1.3 channel in T lymphocytes
Mol.Pharmacol., 75, 2009
2PSU
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Crystal Structure of wild type HIV-1 protease in complex with CARB-AD37
分子名称: ACETATE ION, N-[(1S,2R)-1-BENZYL-3-{(CYCLOPROPYLMETHYL)[(3-METHOXYPHENYL)SULFONYL]AMINO}-2-HYDROXYPROPYL]-N'-METHYLSUCCINAMIDE, PHOSPHATE ION, ...
著者Schiffer, C.A, Nalam, M.N.L.
登録日2007-05-07
公開日2007-06-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Design of Mutation-resistant HIV Protease Inhibitors with the Substrate Envelope Hypothesis.
Chem.Biol.Drug Des., 69, 2007

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