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PDB: 2660 件

3TSI
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Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) stalk domain
分子名称: Hemagglutinin-neuraminidase
著者Bose, S, Welch, B.D, Kors, C.A, Yuan, P, Jardetzky, T.S, Lamb, R.A.
登録日2011-09-13
公開日2011-10-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.651 Å)
主引用文献Structure and mutagenesis of the parainfluenza virus 5 hemagglutinin-neuraminidase stalk domain reveals a four-helix bundle and the role of the stalk in fusion promotion.
J.Virol., 85, 2011
6UJS
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P-glycoprotein mutant-F728A and C952A-with BDE100
分子名称: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
著者Aller, S.G, Le, C.A.
登録日2019-10-03
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.17 Å)
主引用文献Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
1NL6
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Crystal Structure Of The Cysteine Protease Human Cathepsin K In Complex With A Covalent Azepanone Inhibitor
分子名称: 5-(2-MORPHOLIN-4-YLETHOXY)BENZOFURAN-2-CARBOXYLIC ACID ((S)-3-METHYL-1-{(S)-3-OXO-1-[2-(3-PYRIDIN-2-YLPHENYL)ACETYL]AZEPAN-4-YLCARBAMOYL}BUTYL)AMIDE, Cathepsin K
著者Smith, W.W, Janson, C.A, Zhao, B.
登録日2003-01-06
公開日2003-01-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Azepanone-based inhibitors of human and rat cathepsin K
J.Med.Chem., 44, 2001
6UJN
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P-glycoprotein mutant-C952A-with BDE100
分子名称: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
著者Aller, S.G, Le, C.A.
登録日2019-10-03
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.98 Å)
主引用文献Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
4E73
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Crystal structure of JNK1beta-JIP in complex with an azaquinolone inhbitor
分子名称: C-Jun-amino-terminal kinase-interacting protein 1, Mitogen-activated protein kinase 8, methyl 3-(4-{[(1R,2S,3S,5S,7s)-5-aminotricyclo[3.3.1.1~3,7~]dec-2-yl]carbamoyl}benzyl)-4-oxo-1-phenyl-1,4-dihydro-1,8-naphthyridine-2-carboxylate
著者Lukacs, C.M, Janson, C.A.
登録日2012-03-16
公開日2013-05-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Identification of an Adamantyl Azaquinolone JNK Selective Inhibitor.
ACS Med Chem Lett, 3, 2012
6UKY
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STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 12
分子名称: 4-(6-{3-[2-(3-carboxypropanoyl)-6-methoxy-1-benzothiophen-4-yl]propyl}-5-methoxy-1-benzothiophen-2-yl)-4-oxobutanoic acid, fusion protein of Ubiquitin-like protein SMT3 and Stimulator of interferon protein c-terminal domain
著者Lesburg, C.A.
登録日2019-10-06
公開日2020-08-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献An orally available non-nucleotide STING agonist with antitumor activity.
Science, 369, 2020
2LQR
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NMR structure of Ig3 domain of palladin
分子名称: Palladin
著者Beck, M.R, Dixon IV, R.D.S, Otey, C.A, Campbell, S.L, Murphy, G.S.
登録日2012-03-13
公開日2013-01-23
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure and Function of Palladin's Actin Binding Domain.
J.Mol.Biol., 425, 2013
1NE8
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YDCE protein from Bacillus subtilis
分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ACETIC ACID, conserved hypothetical protein YDCE
著者Gogos, A, Mu, H, Bahna, F, Gomez, C.A, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2002-12-10
公開日2003-01-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of YdcE protein from Bacillus subtilis
PROTEINS: STRUCT.,FUNCT.,GENET., 53, 2003
6UD0
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Solution-state NMR structural ensemble of human Tsg101 UEV in complex with K63-linked diubiquitin
分子名称: Tumor susceptibility gene 101 protein, Ubiquitin
著者Strickland, M, Watanabe, S, Bonn, S.M, Camara, C.M, Fushman, D, Carter, C.A, Tjandra, N.
登録日2019-09-18
公開日2021-03-17
最終更新日2024-10-16
実験手法SOLUTION NMR
主引用文献Tsg101/ESCRT-I Recruitment Regulated by the Dual Binding Modes of K63-Linked Diubiquitin
Structure, 2021
3U27
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Crystal structure of ethanolamine utilization protein EutL from Leptotrichia buccalis C-1013-b
分子名称: CALCIUM ION, GLYCEROL, Microcompartments protein, ...
著者Wu, R, Gu, M, Kerfeld, C.A, Salmeen, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2011-10-01
公開日2012-02-08
最終更新日2020-01-29
実験手法X-RAY DIFFRACTION (1.852 Å)
主引用文献Crystal structure of ethanolamine utilization protein EutL from Leptotrichia buccalis C-1013-b
To be Published
3KUY
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DNA Stretching in the Nucleosome Facilitates Alkylation by an Intercalating Antitumor Agent
分子名称: 2-[(2R)-oxiran-2-ylmethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione, DNA (145-MER), Histone H2A, ...
著者Wu, B, Davey, C.A.
登録日2009-11-28
公開日2010-01-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献DNA stretching in the nucleosome facilitates alkylation by an intercalating antitumour agent
Nucleic Acids Res., 38, 2010
2G83
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Structure of activated G-alpha-i1 bound to a nucleotide-state-selective peptide: Minimal determinants for recognizing the active form of a G protein alpha subunit
分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i), alpha-1 subunit, ...
著者Johnston, C.A, Ramer, J.K, Blaesius, R, Kuhlman, B, Arshavsky, V.Y, Siderovski, D.P.
登録日2006-03-01
公開日2006-10-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Minimal Determinants for Binding Activated Galpha from the Structure of a Galpha(i1)-Peptide Dimer.
Biochemistry, 45, 2006
2LDL
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BU of 2ldl by Molmil
Solution NMR Structure of the HIV-1 Exon Splicing Silencer 3
分子名称: RNA (27-MER)
著者Mishler, C, Levengood, J.D, Johnson, C.A, Rajan, P, Znosko, B.M.
登録日2011-05-27
公開日2011-12-28
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution Structure of the HIV-1 Exon Splicing Silencer 3.
J.Mol.Biol., 415, 2012
4IFZ
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BU of 4ifz by Molmil
Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein, Mn(II)-AMP product bound form
分子名称: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, MANGANESE (II) ION, ...
著者Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V.
登録日2012-12-15
公開日2013-02-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9012 Å)
主引用文献The TP0796 Lipoprotein of Treponema pallidum Is a Bimetal-dependent FAD Pyrophosphatase with a Potential Role in Flavin Homeostasis.
J.Biol.Chem., 288, 2013
1M1Z
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BETA-LACTAM SYNTHETASE APO ENZYME
分子名称: BETA-LACTAM SYNTHETASE
著者Miller, M.T, Bachmann, B.O, Townsend, C.A, Rosenzweig, A.C.
登録日2002-06-20
公開日2002-10-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The catalytic cycle of beta -lactam synthetase observed by x-ray crystallographic snapshots
Proc.Natl.Acad.Sci.USA, 99, 2002
1LX6
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Crystal Structure of E. Coli Enoyl Reductase-NAD+ with a Bound Benzamide Inhibitor
分子名称: 3-[(ACETYL-METHYL-AMINO)-METHYL]-4-AMINO-N-METHYL-N-(1-METHYL-1H-INDOL-2-YLMETHYL)-BENZAMIDE, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Smith, W.W, Qiu, X, Janson, C.A.
登録日2002-06-04
公開日2002-09-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of aminopyridine-based inhibitors of bacterial enoyl-ACP reductase (FabI).
J.Med.Chem., 45, 2002
6B4H
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BU of 6b4h by Molmil
Crystal structure of Chaetomium thermophilum Gle1 CTD-Nup42 GBM-IP6 complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, INOSITOL HEXAKISPHOSPHATE, Nucleoporin AMO1, ...
著者Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A.
登録日2017-09-26
公開日2018-06-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
3V5Z
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Structure of FBXL5 hemerythrin domain, C2 cell, grown anaerobically
分子名称: F-box/LRR-repeat protein 5, MU-OXO-DIIRON
著者Tomchick, D.R, Bruick, R.K, Thompson, J.W, Brautigam, C.A.
登録日2011-12-17
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1847 Å)
主引用文献Structural and Molecular Characterization of Iron-sensing Hemerythrin-like Domain within F-box and Leucine-rich Repeat Protein 5 (FBXL5).
J.Biol.Chem., 287, 2012
1LUV
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CATALYTIC AND STRUCTURAL EFFECTS OF AMINO-ACID SUBSTITUTION AT HIS 30 IN HUMAN MANGANESE SUPEROXIDE DISMUTASE: INSERTION OF VAL CGAMMA INTO THE SUBSTRATE ACCESS CHANNEL
分子名称: MANGANESE (II) ION, Superoxide dismutase [Mn]
著者Hearn, A.S, Stroupe, M.E, Ramilo, C.A, Luba, J.P, Cabelli, D.E, Tainer, J.A, Silverman, D.N.
登録日2002-05-23
公開日2002-06-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Catalytic and structural effects of amino acid substitution at histidine 30 in human manganese superoxide dismutase: insertion of valine C gamma into the substrate access channel
Biochemistry, 42, 2003
6V6G
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Crystal structure of CTX-M-14 E166A/P167S/D240G beta-lactamase
分子名称: Beta-lactamase, DI(HYDROXYETHYL)ETHER, SODIUM ION
著者Brown, C.A, Hu, L, Sankaran, B, Prasad, B.V.V, Palzkill, T.G.
登録日2019-12-05
公開日2020-04-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Antagonism between substitutions in beta-lactamase explains a path not taken in the evolution of bacterial drug resistance.
J.Biol.Chem., 295, 2020
4IJZ
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Crystal structure of diaminopimelate epimerase from Escherichia coli
分子名称: Diaminopimelate epimerase, NITRATE ION
著者Hor, L, Dobson, R.C.J, Hutton, C.A, Perugini, M.A.
登録日2012-12-24
公開日2013-02-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Dimerization of bacterial diaminopimelate epimerase is essential for catalysis
J.Biol.Chem., 288, 2013
6V6P
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Crystal structure of CTX-M-14 E166A/D240G beta-lactamase
分子名称: Beta-lactamase, DI(HYDROXYETHYL)ETHER, SULFATE ION
著者Brown, C.A, Hu, L, Sankaran, B, Prasad, B.V.V, Palzkill, T.G.
登録日2019-12-05
公開日2020-04-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Antagonism between substitutions in beta-lactamase explains a path not taken in the evolution of bacterial drug resistance.
J.Biol.Chem., 295, 2020
2LFV
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Solution Structure of the SPOR domain from E. coli DamX
分子名称: Protein damX
著者Williams, K.B, Arends, S.J.R, Popham, D.L, Fowler, C.A, Weiss, D.S.
登録日2011-07-15
公開日2012-07-18
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Nuclear Magnetic Resonance Solution Structure of the Peptidoglycan-Binding SPOR Domain from Escherichia coli DamX: Insights into Septal Localization.
Biochemistry, 52, 2013
6B4E
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Crystal structure of Saccharomyces cerevisiae Gle1 CTD-Nup42 GBM complex
分子名称: 1,2-ETHANEDIOL, Nucleoporin GLE1, Nucleoporin NUP42, ...
著者Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A.
登録日2017-09-26
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
1MJD
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Structure of N-terminal domain of human doublecortin
分子名称: DOUBLECORTIN
著者Kim, M.H, Cierpicki, T, Derewenda, U, Krowarsch, D, Feng, Y, Devedjiev, Y, Dauter, Z, Walsh, C.A, Otlewski, J, Bushweller, J.H, Derewenda, Z.S.
登録日2002-08-27
公開日2003-04-29
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The DCX-domain Tandems of Doublecortin and Doublecortin-like Kinase
Nat.Struct.Biol., 10, 2003

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