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PDB: 47 results

5HYQ
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BU of 5hyq by Molmil
Cetuximab Fab in complex with amidated meditope
Descriptor: Amidated meditope, Cetuximab heavy chain, Cetuximab light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-02-01
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.477 Å)
Cite:Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5I2I
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BU of 5i2i by Molmil
Structure of cetuximab Fab with cyclic F3Q variant of the meditope
Descriptor: Cetuximab Fab heavy chain, Cetuximab Fab light chain, Meditope, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-02-08
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.551 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5ICX
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BU of 5icx by Molmil
Cetuximab Fab in complex with CQFDLSTRRLRCGGSK meditope
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab heavy chain, Cetuximab Fab light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-02-23
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5ID1
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BU of 5id1 by Molmil
Cetuximab Fab in complex with MPT-Cys meditope
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab heavy chain, Cetuximab Fab light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-02-23
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5IR1
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BU of 5ir1 by Molmil
Cetuximab Fab in complex with 3-bromophenylalanine meditope variant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab heavy chain, Cetuximab Fab light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-03-11
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.482 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5ID0
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BU of 5id0 by Molmil
Cetuximab Fab in complex with aminoheptanoic acid-linked meditope
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab heavy chain, Cetuximab Fab light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-02-23
Release date:2016-06-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5ICY
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BU of 5icy by Molmil
Cetuximab Fab in complex with linear meditope
Descriptor: Cetuximab Fab heavy chain, Cetuximab Fab light chain, Meditope, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-02-23
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5IOP
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BU of 5iop by Molmil
Cetuximab Fab in complex with 4-bromophenylalanine meditope variant
Descriptor: Cetuximab Fab, heavy chain, light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-03-08
Release date:2016-10-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.499 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5ICZ
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BU of 5icz by Molmil
Cetuximab Fab in complex with GQFDLSTRRLKG peptide
Descriptor: Cetuximab Fab heavy chain, Cetuximab Fab light chain, Meditope, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-02-23
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5ITF
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BU of 5itf by Molmil
Cetuximab Fab in complex with 2-bromophenylalanine meditope variant
Descriptor: Cetuximab Fab, heavy chain, light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-03-16
Release date:2016-10-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5IV2
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BU of 5iv2 by Molmil
Cetuximab Fab in complex with Arg9Cir meditope variant
Descriptor: Cetuximab Fab, heavy chain, light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-03-18
Release date:2016-10-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.481 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5IVZ
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BU of 5ivz by Molmil
Cetuximab Fab in complex with Arg8Cir meditope variant
Descriptor: Cetuximab Fab, heavy chain, light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2016-03-21
Release date:2016-10-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5J9C
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BU of 5j9c by Molmil
Crystal structure of peroxiredoxin Asp f3 C31S/C61S variant
Descriptor: MAGNESIUM ION, peroxiredoxin Asp f3
Authors:Bzymek, K.P, Williams, J.C, Hong, T.B, Bagramyan, K, Kalkum, M.
Deposit date:2016-04-08
Release date:2016-09-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.956 Å)
Cite:The Crystal Structure of Peroxiredoxin Asp f3 Provides Mechanistic Insight into Oxidative Stress Resistance and Virulence of Aspergillus fumigatus.
Sci Rep, 6, 2016
5J9B
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BU of 5j9b by Molmil
Crystal structure of peroxiredoxin Asp f3
Descriptor: peroxiredoxin Asp f3
Authors:Bzymek, K.P, Williams, J.C, Hong, T.B, Bagramyan, K, Kalkum, M.
Deposit date:2016-04-08
Release date:2016-09-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Crystal Structure of Peroxiredoxin Asp f3 Provides Mechanistic Insight into Oxidative Stress Resistance and Virulence of Aspergillus fumigatus.
Sci Rep, 6, 2016
4Y1L
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BU of 4y1l by Molmil
Ubc9 Homodimer The Missing Link in Poly-SUMO Chain Formation
Descriptor: RWD domain-containing protein 3, SUMO-conjugating enzyme UBC9
Authors:Aileen, Y.A, Ambaye, N.D, Li, Y.J, Vega, R, Bzymek, K, Williams, J.C, Hu, W, Chen, Y.
Deposit date:2015-02-08
Release date:2015-05-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:RWD Domain as an E2 (Ubc9)-Interaction Module.
J.Biol.Chem., 290, 2015
1LOK
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BU of 1lok by Molmil
The 1.20 Angstrom Resolution Crystal Structure of the Aminopeptidase from Aeromonas proteolytica Complexed with Tris: A Tale of Buffer Inhibition
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bacterial leucyl aminopeptidase, SODIUM ION, ...
Authors:Desmarais, W.T, Bienvenue, D.L, Bzymek, K.P, Holz, R.C, Petsko, G.A, Ringe, D.
Deposit date:2002-05-06
Release date:2002-11-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The 1.20 Angstrom Resolution Crystal Structure of the Aminopeptidase from Aeromonas proteolytica Complexed with Tris A tale of Buffer Inhibition
Structure, 10, 2002
4GW1
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BU of 4gw1 by Molmil
cQFD Meditope
Descriptor: Fab heavy chain, Fab light chain, PHOSPHATE ION, ...
Authors:Donaldson, J.M, Zer, C, Avery, K.N, Bzymek, K.P, Horne, D.A, Williams, J.C.
Deposit date:2012-08-31
Release date:2013-10-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GW5
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BU of 4gw5 by Molmil
cQYN meditope - Cetuximab Fab
Descriptor: Fab Heavy Chain, Fab Light Chain, PHOSPHATE ION, ...
Authors:Donaldson, J.M, Zer, C, Avery, K.N, Bzymek, K.P, Horne, D.A, Williams, J.C.
Deposit date:2012-08-31
Release date:2013-10-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HJG
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BU of 4hjg by Molmil
Meditope-enabled trastuzumab
Descriptor: Immunoglobulin G-binding protein A, Protein L fragment, Trastuzumab heavy chain, ...
Authors:Donaldson, J.M, Zer, C, Avery, K.N, Bzymek, K.P, Horne, D.A, Williams, J.C.
Deposit date:2012-10-12
Release date:2013-10-09
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HKZ
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BU of 4hkz by Molmil
Trastuzumab Fab complexed with Protein L and Protein A fragments
Descriptor: CHLORIDE ION, Immunoglobulin G-binding protein A, Protein L fragment, ...
Authors:Avery, K.N, Zer, C, Bzymek, K.P, Williams, J.C.
Deposit date:2012-10-15
Release date:2013-10-09
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 110, 2013
5U6A
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BU of 5u6a by Molmil
CRYSTAL STRUCTURE OF I83E MEDITOPE-ENABLED TRASTUZUMAB WITH AZIDO-PEG3-MEDITOPE
Descriptor: Heavy Chain, Immunoglobulin G binding protein A, Light Chain, ...
Authors:Williams, J.C, Bzymek, K.P, Pucket, J, Avery, K.A, Ma, Y, Xie, J, Zer, C, Horne, D.
Deposit date:2016-12-07
Release date:2018-03-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.736 Å)
Cite:Crystal Structure Of I83E Meditope-Enabled Trastuzumab With Azido-PEG3-Meditope
To Be Published
5U5M
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BU of 5u5m by Molmil
CRYSTAL STRUCTURE OF I83E MEDITOPE-ENABLED TRASTUZUMAB WITH AZIDO-MEDITOPE
Descriptor: AZIDO-PEG4-MEDITOPE, Immunoglobulin G binding protein A, MEMAB TRASTUZUMAB, ...
Authors:Williams, J.C, Bzymek, K.P, Pucket, J, Avery, K.A, Ma, Y, Xie, J, Zer, C, Horne, D.
Deposit date:2016-12-06
Release date:2018-03-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal Structure Of I83E Meditope-Enabled Trastuzumab With Azido-Meditope
To Be Published
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