6EE5
 
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2VH4
 | | Structure of a loop C-sheet serpin polymer | | Descriptor: | TENGPIN | | Authors: | Zhang, Q, Law, R.H.P, Bottomley, S.P, Whisstock, J.C, Buckle, A.M. | | Deposit date: | 2007-11-19 | | Release date: | 2008-01-08 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | A Structural Basis for Loop C-Sheet Polymerization in Serpins.
J.Mol.Biol., 376, 2008
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5J7C
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5J7K
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1YZW
 | | The 2.1A Crystal Structure of the Far-red Fluorescent Protein HcRed: Inherent Conformational Flexibility of the Chromophore | | Descriptor: | DI(HYDROXYETHYL)ETHER, GFP-like non-fluorescent chromoprotein | | Authors: | Wilmann, P.G, Petersen, J, Pettikiriarachchi, A, Buckle, A.M, Devenish, R.J, Prescott, M, Rossjohn, J. | | Deposit date: | 2005-02-28 | | Release date: | 2005-05-17 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The 2.1A Crystal Structure of the Far-red Fluorescent Protein HcRed: Inherent Conformational Flexibility of the Chromophore
J.Mol.Biol., 349, 2005
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5CDZ
 | | Crystal structure of conserpin in the latent state | | Descriptor: | Conserpin in the latent state, GLYCEROL | | Authors: | Porebski, B.T, McGowan, S, Keleher, S, Buckle, A.M. | | Deposit date: | 2015-07-06 | | Release date: | 2016-07-20 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.449 Å) | | Cite: | Smoothing a rugged protein folding landscape by sequence-based redesign.
Sci Rep, 6, 2016
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5CE0
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5CDX
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4U3H
 | | Crystal structure of FN3con | | Descriptor: | FN3con | | Authors: | Porebski, B.T, McGowan, S, Buckle, A.M. | | Deposit date: | 2014-07-21 | | Release date: | 2015-02-11 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Structural and dynamic properties that govern the stability of an engineered fibronectin type III domain.
Protein Eng.Des.Sel., 28, 2015
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4F87
 | | X-ray Crystal Structure of PlyCB | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, PlyCB | | Authors: | McGowan, S, Buckle, A.M, Fischetti, V.A, Nelson, D.C, Whisstock, J.C. | | Deposit date: | 2012-05-17 | | Release date: | 2012-07-25 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | X-ray crystal structure of the streptococcal specific phage lysin PlyC.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4F88
 | | X-ray Crystal Structure of PlyC | | Descriptor: | PlyCA, PlyCB | | Authors: | McGowan, S, Buckle, A.M, Fischetti, V.A, Nelson, D.C, Whisstock, J.C. | | Deposit date: | 2012-05-17 | | Release date: | 2012-07-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | X-ray crystal structure of the streptococcal specific phage lysin PlyC.
Proc.Natl.Acad.Sci.USA, 109, 2012
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1KCQ
 | | Human Gelsolin Domain 2 with a Cd2+ bound | | Descriptor: | CADMIUM ION, GELSOLIN | | Authors: | Kazmirski, S.L, Isaacson, R.L, An, C, Buckle, A, Johnson, C.M, Daggett, V, Fersht, A.R. | | Deposit date: | 2001-11-09 | | Release date: | 2002-01-04 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Loss of a metal-binding site in gelsolin leads to familial amyloidosis-Finnish type.
Nat.Struct.Biol., 9, 2002
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4KGA
 | | Crystal structure of kallikrein-related peptidase 4 | | Descriptor: | 1,2-ETHANEDIOL, Kallikrein-4, NICKEL (II) ION | | Authors: | Ilyichova, O.V, Swedberg, J.E, de Veer, S.J, Sit, K.C, Harris, J.M, Buckle, A.M. | | Deposit date: | 2013-04-29 | | Release date: | 2014-04-30 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics
Sci Rep, 6, 2016
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3JZ4
 | | Crystal structure of E. coli NADP dependent enzyme | | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Succinate-semialdehyde dehydrogenase [NADP+] | | Authors: | Langendorf, C.G, Key, T.L.G, Fenalti, G, Kan, W.T, Buckle, A.M, Caradoc-Davies, T, Tuck, K.L, Law, R.H.P, Whisstock, J.C. | | Deposit date: | 2009-09-22 | | Release date: | 2010-03-16 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The X-ray crystal structure of Escherichia coli succinic semialdehyde dehydrogenase; structural insights into NADP+/enzyme interactions.
Plos One, 5, 2010
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4K1E
 | | Atomic resolution crystal structures of Kallikrein-Related Peptidase 4 complexed with a modified SFTI inhibitor FCQR | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Kallikrein-4, LITHIUM ION, ... | | Authors: | Ilyichova, O.V, Swedberg, J.E, de Veer, S.J, Sit, K.C, Harris, J.M, Buckle, A.M. | | Deposit date: | 2013-04-04 | | Release date: | 2014-04-09 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics
Sci Rep, 6, 2016
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4KEL
 | | Atomic resolution crystal structure of Kallikrein-Related Peptidase 4 complexed with a modified SFTI inhibitor FCQR(N) | | Descriptor: | Kallikrein-4, Trypsin inhibitor 1 | | Authors: | Ilyichova, O.V, Swedberg, J.E, de Veer, S.J, Sit, K.C, Harris, J.M, Buckle, A.M. | | Deposit date: | 2013-04-25 | | Release date: | 2014-04-30 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.148 Å) | | Cite: | KLK4 Inhibition by Cyclic and Acyclic Peptides: Structural and Dynamical Insights into Standard-Mechanism Protease Inhibitors.
Biochemistry, 58, 2019
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1SNG
 | | Structure of a Thermophilic Serpin in the Native State | | Descriptor: | COG4826: Serine protease inhibitor, SULFATE ION | | Authors: | Fulton, K.F, Buckle, A.M, Cabrita, L.D, Irving, J.A, Butcher, R.E, Smith, I, Reeve, S, Lesk, A.M, Bottomley, S.P, Rossjohn, J, Whisstock, J.C. | | Deposit date: | 2004-03-10 | | Release date: | 2004-12-14 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | The high resolution crystal structure of a native thermostable serpin reveals the complex mechanism underpinning the stressed to relaxed transition.
J.Biol.Chem., 280, 2005
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4K8Y
 | | Atomic resolution crystal structures of Kallikrein-Related Peptidase 4 complexed with Sunflower Trypsin Inhibitor (SFTI-1) | | Descriptor: | Kallikrein-4, Trypsin inhibitor 1 | | Authors: | Ilyichova, O.V, Swedberg, J.E, de Veer, S.J, Sit, K.C, Harris, J.M, Buckle, A.M. | | Deposit date: | 2013-04-19 | | Release date: | 2014-04-23 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1 Å) | | Cite: | Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics
Sci Rep, 6, 2016
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1WZ9
 | | The 2.1 A structure of a tumour suppressing serpin | | Descriptor: | Maspin precursor, SULFATE ION | | Authors: | Law, R.H, Irving, J.A, Buckle, A.M, Ruzyla, K, Buzza, M, Bashtannyk-Puhalovich, T.A, Beddoe, T.C, Kim, N, Worrall, D.M, Bottomley, S.P, Bird, P.I, Rossjohn, J, Whisstock, J.C. | | Deposit date: | 2005-03-03 | | Release date: | 2005-03-15 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix.
J.Biol.Chem., 280, 2005
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1FYA
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1FY9
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2H4R
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2H4Q
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3EBG
 | | Structure of the M1 Alanylaminopeptidase from malaria | | Descriptor: | GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ... | | Authors: | McGowan, S, Porter, C.J, Buckle, A.M, Whisstock, J.C. | | Deposit date: | 2008-08-27 | | Release date: | 2009-01-27 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase
Proc.Natl.Acad.Sci.USA, 106, 2009
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3EBH
 | | Structure of the M1 Alanylaminopeptidase from malaria complexed with bestatin | | Descriptor: | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, GLYCEROL, M1 family aminopeptidase, ... | | Authors: | McGowan, S, Porter, C.J, Buckle, A.M, Whisstock, J.C. | | Deposit date: | 2008-08-27 | | Release date: | 2009-01-27 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase
Proc.Natl.Acad.Sci.USA, 106, 2009
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