4OYY
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1M6C
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![BU of 1m6c by Molmil](/molmil-images/mine/1m6c) | V68N MYOGLOBIN WITH CO | Descriptor: | CARBON MONOXIDE, PROTEIN (MYOGLOBIN), PROTOPORPHYRIN IX CONTAINING FE | Authors: | Murshudov, G.N, Krzywda, S, Brzozowski, A.M, Jaskolski, M, Scott, E.E, Klizas, S.A, Gibson, Q.H, Olson, J.S, Wilkinson, A.J. | Deposit date: | 1998-08-12 | Release date: | 1998-08-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Stabilizing bound O2 in myoglobin by valine68 (E11) to asparagine substitution. Biochemistry, 37, 1998
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1OJJ
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![BU of 1ojj by Molmil](/molmil-images/mine/1ojj) | Anatomy of glycosynthesis: Structure and kinetics of the Humicola insolens Cel7BE197A and E197S glycosynthase mutants | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOGLUCANASE I, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, ... | Authors: | Ducros, V.M.-A, Tarling, C.A, Zechel, D.L, Brzozowski, A.M, Frandsen, T.P, Von Ossowski, I, Schulein, M, Withers, S.G, Davies, G.J. | Deposit date: | 2003-07-10 | Release date: | 2004-01-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Anatomy of Glycosynthesis: Structure and Kinetics of the Humicola Insolens Cel7B E197A and E197S Glycosynthase Mutants Chem.Biol., 10, 2003
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2C0D
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![BU of 2c0d by Molmil](/molmil-images/mine/2c0d) | Structure of the mitochondrial 2-cys peroxiredoxin from Plasmodium falciparum | Descriptor: | THIOREDOXIN PEROXIDASE 2 | Authors: | Boucher, I.W, Brannigan, J.A, Wilkinson, A.J, Brzozowski, A.M, Muller, S. | Deposit date: | 2005-09-01 | Release date: | 2006-11-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structural and Biochemical Characterisation of a Mitochondrial Peroxiredoxin from Plasmodium Falciparum Mol.Microbiol., 61, 2006
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1OJK
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![BU of 1ojk by Molmil](/molmil-images/mine/1ojk) | Anatomy of glycosynthesis: Structure and kinetics of the Humicola insolens Cel7BE197A and E197S glycosynthase mutants | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOGLUCANASE I, GLYCEROL, ... | Authors: | Ducros, V.M.-A, Tarling, C.A, Zechel, D.L, Brzozowski, A.M, Frandsen, T.P, Von Ossowski, I, Schulein, M, Withers, S.G, Davies, G.J. | Deposit date: | 2003-07-10 | Release date: | 2004-01-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Anatomy of Glycosynthesis: Structure and Kinetics of the Humicola Insolens Cel7B E197A and E197S Glycosynthase Mutants Chem.Biol., 10, 2003
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1OJI
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![BU of 1oji by Molmil](/molmil-images/mine/1oji) | Anatomy of glycosynthesis: Structure and kinetics of the Humicola insolens Cel7B E197A and E197S glycosynthase mutants | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOGLUCANASE I, GLYCEROL | Authors: | Ducros, V.M.-A, Tarling, C.A, Zechel, D.L, Brzozowski, A.M, Frandsen, T.P, Von Ossowski, I, Schulein, M, Withers, S.G, Davies, G.J. | Deposit date: | 2003-07-10 | Release date: | 2004-01-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Anatomy of Glycosynthesis: Structure and Kinetics of the Humicola Insolens Cel7B E197A and E197S Glycosynthase Mutants Chem.Biol., 10, 2003
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2BSX
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![BU of 2bsx by Molmil](/molmil-images/mine/2bsx) | Crystal structure of the Plasmodium falciparum purine nucleoside phosphorylase complexed with inosine | Descriptor: | INOSINE, PURINE NUCLEOSIDE PHOSPHORYLASE | Authors: | Schnick, C, Brzozowski, A.M, Dodson, E.J, Murshudov, G.N, Brannigan, J.A, Wilkinson, A.J. | Deposit date: | 2005-05-24 | Release date: | 2005-08-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of Plasmodium Falciparum Purine Nucleoside Phosphorylase Complexed with Sulfate and its Natural Substrate Inosine Acta Crystallogr.,Sect.D, 61, 2005
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1MWD
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![BU of 1mwd by Molmil](/molmil-images/mine/1mwd) | WILD TYPE DEOXY MYOGLOBIN | Descriptor: | PROTEIN (MYOGLOBIN), PROTOPORPHYRIN IX CONTAINING FE | Authors: | Murshudov, G.N, Krzywda, S, Brzozowski, A.M, Jaskolski, M, Scott, E.E, Klizas, A.A, Gibson, Q.H, Olson, J.S, Wilkinson, A.J. | Deposit date: | 1998-08-11 | Release date: | 1998-08-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Stabilizing bound O2 in myoglobin by valine68 (E11) to asparagine substitution. Biochemistry, 37, 1998
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1GWQ
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1QFK
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![BU of 1qfk by Molmil](/molmil-images/mine/1qfk) | STRUCTURE OF HUMAN FACTOR VIIA AND ITS IMPLICATIONS FOR THE TRIGGERING OF BLOOD COAGULATION | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COAGULATION FACTOR VIIA HEAVY CHAIN, ... | Authors: | Pike, A.C.W, Brzozowski, A.M, Roberts, S.M, Olsen, O.H, Persson, E. | Deposit date: | 1999-04-12 | Release date: | 1999-08-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of human factor VIIa and its implications for the triggering of blood coagulation. Proc.Natl.Acad.Sci.USA, 96, 1999
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1QHP
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![BU of 1qhp by Molmil](/molmil-images/mine/1qhp) | FIVE-DOMAIN ALPHA-AMYLASE FROM BACILLUS STEAROTHERMOPHILUS, MALTOSE COMPLEX | Descriptor: | ALPHA-AMYLASE, CALCIUM ION, SULFATE ION, ... | Authors: | Dauter, Z, Dauter, M, Brzozowski, A.M, Christensen, S, Borchert, T.V, Beier, L, Wilson, K.S, Davies, G.J. | Deposit date: | 1999-05-25 | Release date: | 2000-05-31 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | X-ray structure of Novamyl, the five-domain "maltogenic" alpha-amylase from Bacillus stearothermophilus: maltose and acarbose complexes at 1.7A resolution. Biochemistry, 38, 1999
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1QHO
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![BU of 1qho by Molmil](/molmil-images/mine/1qho) | FIVE-DOMAIN ALPHA-AMYLASE FROM BACILLUS STEAROTHERMOPHILUS, MALTOSE/ACARBOSE COMPLEX | Descriptor: | ALPHA-AMYLASE, CALCIUM ION, SULFATE ION, ... | Authors: | Dauter, Z, Dauter, M, Brzozowski, A.M, Christensen, S, Borchert, T.V, Beier, L, Wilson, K.S, Davies, G.J. | Deposit date: | 1999-05-25 | Release date: | 2000-05-31 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | X-ray structure of Novamyl, the five-domain "maltogenic" alpha-amylase from Bacillus stearothermophilus: maltose and acarbose complexes at 1.7A resolution. Biochemistry, 38, 1999
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3O0E
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![BU of 3o0e by Molmil](/molmil-images/mine/3o0e) | Crystal structure of OmpF in complex with colicin peptide OBS1 | Descriptor: | Colicin-E9, Porin OmpF, octyl beta-D-glucopyranoside | Authors: | Wojdyla, J.A, Housden, N.G, Korczynska, J, Grishkovskaya, I, Kirkpatrick, N, Brzozowski, A.M, Kleanthous, C. | Deposit date: | 2010-07-19 | Release date: | 2010-12-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Directed epitope delivery across the Escherichia coli outer membrane through the porin OmpF. Proc.Natl.Acad.Sci.USA, 107, 2010
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1GWR
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2J7Y
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![BU of 2j7y by Molmil](/molmil-images/mine/2j7y) | STRUCTURE OF 17-EPIESTRIOL-BOUND ESTROGEN RECEPTOR BETA LBD IN COMPLEX WITH LXXLL MOTIF FROM NCOA5 | Descriptor: | (16ALPHA,17ALPHA)-ESTRA-1,3,5(10)-TRIENE-3,16,17-TRIOL, 1,2-ETHANEDIOL, BICARBONATE ION, ... | Authors: | Pike, A.C.W, Brzozowski, A.M, Hubbard, R.E, Walton, J, Bonn, T, Thorsell, A.-G, Engstrom, O, Ljunggren, J, Gustaffson, J.-A, Carlquist, M. | Deposit date: | 2006-10-17 | Release date: | 2006-11-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of Agonist-Bound Estrogen Receptor Beta Lbd in Complex with Lxxll Motif from Ncoa5 To be Published
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2J5S
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![BU of 2j5s by Molmil](/molmil-images/mine/2j5s) | Structural of ABDH, a beta-diketone hydrolase from the Cyanobacterium Anabaena sp. PCC 7120 bound to (S)-3-oxocyclohexyl acetic acid | Descriptor: | (S)-CYCLOHEXANONE-2-ACETATE, BETA-DIKETONE HYDROLASE, NICKEL (II) ION | Authors: | Bennett, J.P, Whittingham, J.L, Brzozowski, A.M, Leonard, P.M, Grogan, G. | Deposit date: | 2006-09-19 | Release date: | 2007-01-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Structural Characterisation of a Beta Diketone Hydrolase from the Cyanobacterium Anabaena Sp. Pcc 7120 in Native and Product Bound Forms, a Coenzyme A-Independent Member of the Crotonase Suprafamily Biochemistry, 46, 2007
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2J5I
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![BU of 2j5i by Molmil](/molmil-images/mine/2j5i) | Crystal Structure of Hydroxycinnamoyl-CoA Hydratase-Lyase | Descriptor: | P-HYDROXYCINNAMOYL COA HYDRATASE/LYASE | Authors: | Leonard, P.M, Brzozowski, A.M, Lebedev, A, Marshall, C.M, Smith, D.J, Verma, C.S, Walton, N.J, Grogan, G. | Deposit date: | 2006-09-18 | Release date: | 2006-12-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The 1.8 A Resolution Structure of Hydroxycinnamoyl- Coenzyme a Hydratase-Lyase (Hchl) from Pseudomonas Fluorescens, an Enzyme that Catalyses the Transformation of Feruloyl-Coenzyme a to Vanillin. Acta Crystallogr.,Sect.D, 62, 2006
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2J7X
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![BU of 2j7x by Molmil](/molmil-images/mine/2j7x) | STRUCTURE OF ESTRADIOL-BOUND ESTROGEN RECEPTOR BETA LBD IN COMPLEX WITH LXXLL MOTIF FROM NCOA5 | Descriptor: | 1,2-ETHANEDIOL, BICARBONATE ION, ESTRADIOL, ... | Authors: | Pike, A.C.W, Brzozowski, A.M, Hubbard, R.E, Walton, J, Bonn, T, Thorsell, A.-G, Engstrom, O, Ljunggren, J, Gustaffson, J.-A, Carlquist, M. | Deposit date: | 2006-10-17 | Release date: | 2006-11-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of Agonist-Bound Estrogen Receptor Beta Lbd in Complex with Lxxll Motif from Ncoa5 To be Published
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4CXL
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![BU of 4cxl by Molmil](/molmil-images/mine/4cxl) | Human insulin analogue (D-ProB8)-insulin | Descriptor: | CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN | Authors: | Kosinova, L, Veverka, V, Novotna, P, Collinsova, M, Urbanova, M, Jiracek, J, Moody, N.R, Turkenburg, J.P, Brzozowski, A.M, Zakova, L. | Deposit date: | 2014-04-07 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | An Insight Into Structural and Biological Relevance of the T/R Transition of the B-Chain N-Terminus in Human Insulin. Biochemistry, 53, 2014
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4CXN
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![BU of 4cxn by Molmil](/molmil-images/mine/4cxn) | Crystal structure of human insulin analogue (NMe-AlaB8)-insulin crystal form I | Descriptor: | INSULIN A CHAIN, INSULIN B CHAIN | Authors: | Kosinova, L, Veverka, V, Novotna, P, Collinsova, M, Urbanova, M, Jiracek, J, Moody, N.R, Turkenburg, J.P, Brzozowski, A.M, Zakova, L. | Deposit date: | 2014-04-07 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | An Insight Into Structural and Biological Relevance of the T/R Transition of the B-Chain N-Terminus in Human Insulin. Biochemistry, 53, 2014
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4B11
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![BU of 4b11 by Molmil](/molmil-images/mine/4b11) | Plasmodium vivax N-myristoyltransferase with a bound benzofuran inhibitor (compound 13) | Descriptor: | 2-oxopentadecyl-CoA, 3-methyl-N-(naphthalen-1-ylmethyl)-4-piperidin-4-yloxy-1-benzofuran-2-carboxamide, CHLORIDE ION, ... | Authors: | Yu, Z, Brannigan, J.A, Moss, D.K, Brzozowski, A.M, Wilkinson, A.J, Holder, A.A, Tate, E.W, Leatherbarrow, R.J. | Deposit date: | 2012-07-06 | Release date: | 2012-10-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Design and Synthesis of Inhibitors of Plasmodium Falciparum N-Myristoyltransferase, a Promising Target for Anti-Malarial Drug Discovery. J.Med.Chem., 55, 2012
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4B10
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![BU of 4b10 by Molmil](/molmil-images/mine/4b10) | Plasmodium vivax N-myristoyltransferase with a non-hydrolysable co- factor | Descriptor: | 2-oxopentadecyl-CoA, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | Authors: | Yu, Z, Brannigan, J.A, Moss, D.K, Brzozowski, A.M, Wilkinson, A.J, Holder, A.A, Tate, E.W, Leatherbarrow, R.J. | Deposit date: | 2012-07-06 | Release date: | 2012-10-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Design and Synthesis of Inhibitors of Plasmodium Falciparum N-Myristoyltransferase, a Promising Target for Anti-Malarial Drug Discovery. J.Med.Chem., 55, 2012
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4B13
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![BU of 4b13 by Molmil](/molmil-images/mine/4b13) | Plasmodium vivax N-myristoyltransferase with a bound benzofuran inhibitor (compound 25) | Descriptor: | 2-oxopentadecyl-CoA, 4-{[2-(3-benzyl-1,2,4-oxadiazol-5-yl)-3-methyl-1-benzofuran-4-yl]oxy}piperidine, CHLORIDE ION, ... | Authors: | Yu, Z, Brannigan, J.A, Moss, D.K, Brzozowski, A.M, Wilkinson, A.J, Holder, A.A, Tate, E.W, Leatherbarrow, R.J. | Deposit date: | 2012-07-06 | Release date: | 2012-10-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Design and Synthesis of Inhibitors of Plasmodium Falciparum N-Myristoyltransferase, a Promising Target for Antimalarial Drug Discovery. J.Med.Chem., 55, 2012
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2J5G
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![BU of 2j5g by Molmil](/molmil-images/mine/2j5g) | The Native structure of a beta-Diketone Hydrolase from the Cyanobacterium Anabaena sp. PCC 7120 | Descriptor: | ALR4455 PROTEIN, SULFATE ION | Authors: | Bennett, J.P, Whittingham, J.L, Brzozowski, A.M, Leonard, P.M, Grogan, G. | Deposit date: | 2006-09-18 | Release date: | 2007-01-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Structural Characterisation of a Beta Diketone Hydrolase from the Cyanobacterium Anabaena Sp. Pcc 7120 in Native and Product Bound Forms, a Coenzyme A-Independent Member of the Crotonase Suprafamily Biochemistry, 46, 2007
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4B12
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![BU of 4b12 by Molmil](/molmil-images/mine/4b12) | Plasmodium vivax N-myristoyltransferase with a bound benzofuran inhibitor (compound 23) | Descriptor: | 1-[3-methyl-4-(piperidin-4-yloxy)-1-benzofuran-2-yl]-3-phenylpropan-1-one, 2-oxopentadecyl-CoA, CHLORIDE ION, ... | Authors: | Yu, Z, Brannigan, J.A, Moss, D.K, Brzozowski, A.M, Wilkinson, A.J, Holder, A.A, Tate, E.W, Leatherbarrow, R.J. | Deposit date: | 2012-07-06 | Release date: | 2012-10-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Design and Synthesis of Inhibitors of Plasmodium Falciparum N-Myristoyltransferase, a Promising Target for Anti-Malarial Drug Discovery. J.Med.Chem., 55, 2012
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