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PDB: 140 件

2ISH
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Botulinum Neurotoxin A Light Chain WT Crystal Form C
分子名称: Neurotoxin BoNT/A, ZINC ION
著者Brunger, A.T, Stegmann, C.M.
登録日2006-10-17
公開日2006-11-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons.
J.Biol.Chem., 282, 2007
2ISE
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BU of 2ise by Molmil
Botulinum Neurotoxin A Light Chain WT Crystal Form A
分子名称: Neurotoxin BoNT/A, ZINC ION
著者Brunger, A.T, Stegmann, C.M.
登録日2006-10-17
公開日2006-11-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons.
J.Biol.Chem., 282, 2007
2ISG
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BU of 2isg by Molmil
Botulinum Neurotoxin A Light Chain WT Crystal Form B
分子名称: NICKEL (II) ION, Neurotoxin BoNT/A, ZINC ION
著者Brunger, A.T, Stegmann, C.M.
登録日2006-10-17
公開日2006-11-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons.
J.Biol.Chem., 282, 2007
3J97
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BU of 3j97 by Molmil
Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State II)
分子名称: Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ...
著者Zhao, M, Wu, S, Cheng, Y, Brunger, A.T.
登録日2014-12-05
公開日2015-01-28
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (7.8 Å)
主引用文献Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
6MDO
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BU of 6mdo by Molmil
The D1 and D2 domain rings of NSF engaging the SNAP-25 N-terminus within the 20S supercomplex (focused refinement on D1/D2 rings, class 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Synaptosomal-associated protein 25, ...
著者White, K.I, Zhao, M, Brunger, A.T.
登録日2018-09-04
公開日2018-09-19
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural principles of SNARE complex recognition by the AAA+ protein NSF.
Elife, 7, 2018
6MDP
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BU of 6mdp by Molmil
The D1 and D2 domain rings of NSF engaging the SNAP-25 N-terminus within the 20S supercomplex (focused refinement on D1/D2 rings, class 2)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Synaptosomal-associated protein 25, ...
著者White, K.I, Zhao, M, Brunger, A.T.
登録日2018-09-04
公開日2018-09-19
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural principles of SNARE complex recognition by the AAA+ protein NSF.
Elife, 7, 2018
8CZI
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BU of 8czi by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with extended HR2
分子名称: Scaffolded Spike protein S2' HR1, Spike protein S2' HR2
著者Yang, K, Brunger, A.T.
登録日2022-05-24
公開日2022-09-07
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.22 Å)
主引用文献Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein.
Proc.Natl.Acad.Sci.USA, 119, 2022
8FA1
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BU of 8fa1 by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with N969K mutation
分子名称: Ferritin, Dps family protein and Spike protein S2' chimera, Spike protein S2' HR2
著者Yang, K, Brunger, A.T.
登録日2022-11-25
公開日2023-03-29
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.51 Å)
主引用文献Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FA2
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BU of 8fa2 by Molmil
Cryo-EM structure of the SARS-CoV-2 Omicron HR1-42G complex
分子名称: Scaffolded Spike protein S2' HR1, Spike protein S2' 42G
著者Yang, K, Brunger, A.T.
登録日2022-11-25
公開日2023-03-29
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.82 Å)
主引用文献Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor.
Proc.Natl.Acad.Sci.USA, 120, 2023
3BIX
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BU of 3bix by Molmil
Crystal structure of the extracellular esterase domain of Neuroligin-1
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, NICKEL (II) ION, ...
著者Arac, D, Boucard, A.A, Ozkan, E, Strop, P, Newell, E, Sudhof, T.C, Brunger, A.T.
登録日2007-12-01
公開日2007-12-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of Neuroligin-1 and the Neuroligin-1/Neurexin-1beta Complex Reveal Specific Protein-Protein and Protein-Ca(2+) Interactions.
Neuron, 56, 2007
3BBG
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BU of 3bbg by Molmil
MULTI-CONFORMER STRUCTURE OF RAGWEED POLLEN ALLERGEN FROM AMBROSIA TRIFIDA V, NMR, 2 STRUCTURES
分子名称: POLLEN ALLERGEN 5
著者Warren, G.L, Tuner, C.J, Petsko, G.A, Brunger, A.T.
登録日1998-04-24
公開日1998-06-17
最終更新日2024-10-23
実験手法SOLUTION NMR
主引用文献A Highly Precise Solution 1H NMR Structure of Ragweed Allergen Amb. T. V
To be Published
1QQE
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BU of 1qqe by Molmil
CRYSTAL STRUCTURE OF THE VESICULAR TRANSPORT PROTEIN SEC17
分子名称: VESICULAR TRANSPORT PROTEIN SEC17
著者Rice, L.M, Brunger, A.T.
登録日1999-06-04
公開日1999-09-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the vesicular transport protein Sec17: implications for SNAP function in SNARE complex disassembly.
Mol.Cell, 4, 1999
4WMG
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BU of 4wmg by Molmil
Structure of hen egg-white lysozyme from a microfludic harvesting device using synchrotron radiation (2.5A)
分子名称: Lysozyme C
著者Lyubimov, A.Y, Murray, T.D, Koehl, A, Uervirojnangkoorn, M, Zeldin, O.B, Cohen, A.E, Soltis, S.M, Baxter, E.M, Brewster, A.S, Sauter, N.K, Brunger, A.T, Berger, J.M.
登録日2014-10-08
公開日2015-04-22
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Capture and X-ray diffraction studies of protein microcrystals in a microfluidic trap array.
Acta Crystallogr.,Sect.D, 71, 2015
4WY4
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BU of 4wy4 by Molmil
Crystal structure of autophagic SNARE complex
分子名称: Synaptosomal-associated protein 29, Syntaxin-17, Vesicle-associated membrane protein 8
著者Zhao, M, Brunger, A.T.
登録日2014-11-15
公開日2015-02-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes.
Nature, 520, 2015
3BBP
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BU of 3bbp by Molmil
Rab6-GTP:GCC185 Rab binding domain complex
分子名称: GRIP and coiled-coil domain-containing protein 2, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Schweizer Burguete, A, Fenn, T.D, Brunger, A.T, Pfeffer, S.R.
登録日2007-11-09
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185.
Cell(Cambridge,Mass.), 132, 2008
4FE1
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BU of 4fe1 by Molmil
Improving the Accuracy of Macromolecular Structure Refinement at 7 A Resolution
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ...
著者Fromme, R, Adams, P.D, Fromme, P, Levitt, M, Schroeder, G.F, Brunger, A.T.
登録日2012-05-29
公開日2012-08-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (4.9228 Å)
主引用文献Improving the accuracy of macromolecular structure refinement at 7 A resolution.
Structure, 20, 2012
6MDN
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BU of 6mdn by Molmil
The 20S supercomplex engaging the SNAP-25 N-terminus (class 2)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Alpha-soluble NSF attachment protein, ...
著者White, K.I, Zhao, M, Brunger, A.T.
登録日2018-09-04
公開日2018-09-19
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structural principles of SNARE complex recognition by the AAA+ protein NSF.
Elife, 7, 2018
6MDM
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BU of 6mdm by Molmil
The 20S supercomplex engaging the SNAP-25 N-terminus (class 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Alpha-soluble NSF attachment protein, ...
著者White, K.I, Zhao, M, Brunger, A.T.
登録日2018-09-04
公開日2018-09-19
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structural principles of SNARE complex recognition by the AAA+ protein NSF.
Elife, 7, 2018
6WVW
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BU of 6wvw by Molmil
Crystal structure of the R59P-SNAP25 containing SNARE complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Synaptosomal-associated protein 25, ...
著者Zhou, Q, White, K.I, Brunger, A.T.
登録日2020-05-07
公開日2021-03-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Role of Aberrant Spontaneous Neurotransmission in SNAP25-Associated Encephalopathies.
Neuron, 109, 2021
3BIW
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BU of 3biw by Molmil
Crystal structure of the Neuroligin-1/Neurexin-1beta synaptic adhesion complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Arac, D, Boucard, A.A, Ozkan, E, Strop, P, Newell, E, Sudhof, T.C, Brunger, A.T.
登録日2007-12-01
公開日2007-12-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structures of Neuroligin-1 and the Neuroligin-1/Neurexin-1beta Complex Reveal Specific Protein-Protein and Protein-Ca(2+) Interactions.
Neuron, 56, 2007
9BRU
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BU of 9bru by Molmil
Intact V-ATPase State 1 in synaptophysin knock-out isolated synaptic vesicles
分子名称: Renin receptor cytoplasmic fragment, Ribonuclease kappa, V-type proton ATPase 116 kDa subunit a 1, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-11
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
9BRT
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BU of 9brt by Molmil
Intact V-ATPase State 1 and synaptophysin complex in mouse brain isolated synaptic vesicles
分子名称: Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-11
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
9BRA
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BU of 9bra by Molmil
Intact V-ATPase State 2 and synaptophysin complex in mouse brain isolated synaptic vesicles
分子名称: Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-11
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
9BRR
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BU of 9brr by Molmil
Intact V-ATPase State 3 in synaptophysin knock-out isolated synaptic vesicles
分子名称: Renin receptor cytoplasmic fragment, Ribonuclease kappa, V-type proton ATPase 116 kDa subunit a 1, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-11
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
9BRS
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BU of 9brs by Molmil
Intact V-ATPase State 2 in synaptophysin knock-out isolated synaptic vesicles
分子名称: Renin receptor cytoplasmic fragment, Ribonuclease kappa, V-type proton ATPase 116 kDa subunit a 1, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-11
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024

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