7BJV
| Crystal structure of the ligand-binding domains of the heterodimer EcR/USP bound to the synthetic agonist BYI09181 | Descriptor: | DI(HYDROXYETHYL)ETHER, Ecdysone Receptor, L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE, ... | Authors: | Browning, C, McEwen, A.G, Billas, I.M.L. | Deposit date: | 2021-01-14 | Release date: | 2021-04-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Nonsteroidal ecdysone receptor agonists use a water channel for binding to the ecdysone receptor complex EcR/USP. J Pestic Sci, 46, 2021
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7BJU
| Crystal structure of the ligand-binding domains of the heterodimer EcR/USP bound to the synthetic agonist BYI08346 | Descriptor: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, DI(HYDROXYETHYL)ETHER, Ecdysone Receptor, ... | Authors: | Browning, C, McEwen, A.G, Billas, I.M.L. | Deposit date: | 2021-01-14 | Release date: | 2021-04-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Nonsteroidal ecdysone receptor agonists use a water channel for binding to the ecdysone receptor complex EcR/USP. J Pestic Sci, 46, 2021
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6BDG
| HFQ monomer in spacegroup p6 at 1.93 angstrom resolution | Descriptor: | RNA-binding protein Hfq | Authors: | Brown, C, Zhang, K, Seo, C, Ellis, M.J, Hanniford, D.B, Junop, M. | Deposit date: | 2017-10-23 | Release date: | 2017-11-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.964 Å) | Cite: | HFQ monomer in spacegroup p6 at 1.93 angstrom resolution To Be Published
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4RU4
| Crystal structure of the tailspike protein gp49 from Pseudomonas phage LKA1 | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, SODIUM ION, ... | Authors: | Browning, C, Shneider, M.M, Leiman, P.G. | Deposit date: | 2014-11-18 | Release date: | 2015-11-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.903 Å) | Cite: | The O-specific polysaccharide lyase from the phage LKA1 tailspike reduces Pseudomonas virulence. Sci Rep, 7, 2017
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4RU5
| Crystal Structure of the Pseudomonas phage phi297 tailspike gp61 | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | Authors: | Browning, C, Sycheva, L.V, Shneider, M.M, Leiman, P.G. | Deposit date: | 2014-11-18 | Release date: | 2015-11-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | The O-specific polysaccharide lyase from the phage LKA1 tailspike reduces Pseudomonas virulence. Sci Rep, 7, 2017
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4RU3
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6BD0
| I-OnuI K227Y, D236A bound to cognate substrate (pre-cleavage complex) | Descriptor: | CALCIUM ION, DNA (25-MER), Ribosomal protein 3/homing endonuclease-like protein fusion | Authors: | Brown, C, Zhang, K, Laforet, M, McMurrough, T.A, Gloor, G.B, Edgell, D.R, Junop, M. | Deposit date: | 2017-10-20 | Release date: | 2018-10-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | I-OnuI K227Y, D236A bound to cognate substrate (pre-cleavage complex) To Be Published
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6BDB
| I-OnuI K227Y, D236A bound to A3G substrate (pre-cleavage complex) | Descriptor: | DNA (26-MER), Ribosomal protein 3/homing endonuclease-like protein fusion | Authors: | Brown, C, Zhang, K, McMurrough, T.A, Laforet, M, Gloor, G.B, Edgell, D.R, Junop, M. | Deposit date: | 2017-10-22 | Release date: | 2018-10-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | I-OnuI K227Y, D236A bound to A3G substrate (pre-cleavage complex) To Be Published
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6BCH
| I-LtrI E29D bound to cognate substrate (nicked complex) | Descriptor: | DNA (26-MER), DNA (5'-D(*GP*GP*TP*CP*TP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP*T)-3'), DNA (5'-D(*TP*AP*GP*GP*AP*GP*CP*AP*TP*TP*T)-3'), ... | Authors: | Brown, C, Zhang, K, McMurrough, T.A, Gloor, G.B, Edgell, D.R, Junop, M. | Deposit date: | 2017-10-20 | Release date: | 2018-10-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | I-LtrI E29D bound to cognate substrate (nicked complex) To Be Published
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6BDA
| Wild-type I-OnuI bound to A3G substrate (post-cleavage complex) | Descriptor: | Cleaved Cognate DNA strand, +11 sense, Cleaved cognate DNA strand, ... | Authors: | Brown, C, Zhang, K, Laforet, M, McMurrough, T, Gloor, G.B, Edgell, D.R, Junop, M. | Deposit date: | 2017-10-22 | Release date: | 2018-10-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Wild-type I-OnuI bound to A3G substrate (post-cleavage complex) To Be Published
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6BCN
| I-LtrI E184D bound to cognate substrate (pre-cleavage complex) | Descriptor: | CALCIUM ION, DNA (26-MER), Ribosomal protein 3/homing endonuclease-like fusion protein | Authors: | Brown, C, Zhang, K, McMurrough, T.A, Gloor, G.B, Edgell, D.R, Junop, M. | Deposit date: | 2017-10-20 | Release date: | 2018-10-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases. Nucleic Acids Res., 46, 2018
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6BCG
| I-LtrI A28G bound to cognate substrate (pre-cleavage complex) | Descriptor: | CALCIUM ION, DNA (26-MER), Ribosomal protein 3/homing endonuclease-like fusion protein | Authors: | Brown, C, Zhang, K, McMurrough, T.A, Gloor, G.B, Edgell, D.R, Junop, M. | Deposit date: | 2017-10-20 | Release date: | 2018-10-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases. Nucleic Acids Res., 46, 2018
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6BCF
| I-LtrI G183A bound to cognate substrate (pre-cleavage complex) | Descriptor: | CALCIUM ION, DNA (26-MER), Ribosomal protein 3/homing endonuclease-like fusion protein | Authors: | Brown, C, Zhang, K, McMurrough, T.A, Gloor, G.B, Edgell, D.R, Junop, M. | Deposit date: | 2017-10-20 | Release date: | 2018-10-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases. Nucleic Acids Res., 46, 2018
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6BCT
| I-LtrI E184D bound to non-cognate C4 substrate (pre-cleavage complex) | Descriptor: | CALCIUM ION, DNA (26-MER), DNA (27-MER), ... | Authors: | Brown, C, Zhang, K, McMurrough, T.A, Gloor, G.B, Edgell, D.R, Junop, M. | Deposit date: | 2017-10-20 | Release date: | 2018-10-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases. Nucleic Acids Res., 46, 2018
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6BCE
| Wild-type I-LtrI bound to cognate substrate (pre-cleavage complex) | Descriptor: | CALCIUM ION, DNA (27-MER), Ribosomal protein 3/homing endonuclease-like fusion protein | Authors: | Brown, C, Zhang, K, McMurrough, T.A, Gloor, G.B, Edgell, D.R, Junop, M. | Deposit date: | 2017-10-20 | Release date: | 2018-10-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases. Nucleic Acids Res., 46, 2018
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6BCI
| Wild-type I-LtrI bound to non-cognate C4 substrate (pre-cleavage complex) | Descriptor: | CALCIUM ION, DNA (27-MER), Ribosomal protein 3/homing endonuclease-like fusion protein | Authors: | Brown, C, Zhang, K, McMurrough, T.A, Gloor, G.B, Edgell, D.R, Junop, M. | Deposit date: | 2017-10-20 | Release date: | 2018-10-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases. Nucleic Acids Res., 46, 2018
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5EWP
| ARO (armadillo repeats only protein) from Plasmodium falciparum | Descriptor: | ARO (armadillo repeats only protein) | Authors: | Brown, C, Zhang, K, Emery, J, Prusty, D, Wetzel, J, Heincke, D, Gilberger, T, Junop, M. | Deposit date: | 2015-11-20 | Release date: | 2016-01-27 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | ARO (armadillo repeats only protein) from Plasmodium falciparum To Be Published
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3PQI
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3PQH
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3QR7
| Crystal structure of the C-terminal fragment of the bacteriophage P2 membrane-piercing protein gpV | Descriptor: | Baseplate assembly protein V, CALCIUM ION, CHLORIDE ION, ... | Authors: | Browning, C, Shneider, M, Leiman, P.G. | Deposit date: | 2011-02-17 | Release date: | 2012-02-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (0.94 Å) | Cite: | Phage pierces the host cell membrane with the iron-loaded spike. Structure, 20, 2012
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3QR8
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8V2T
| Phosphoheptose isomerase GMHA from Burkholderia pseudomallei bound to inhibitor Mut148591 | Descriptor: | 1,5,6-trideoxy-6,6-difluoro-1-(N-hydroxyformamido)-6-phosphono-D-ribo-hexitol, CHLORIDE ION, Phosphoheptose isomerase, ... | Authors: | Junop, M.S, Brown, C, Szabla, R. | Deposit date: | 2023-11-23 | Release date: | 2023-12-06 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.402 Å) | Cite: | Potentiating Activity of GmhA Inhibitors on Gram-Negative Bacteria. J.Med.Chem., 2024
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8V4J
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6ORJ
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6PYT
| CryoEM Structure of Pyocin R2 - precontracted - trunk | Descriptor: | Pyocin sheath PA0622, Pyocin tube PA0623 | Authors: | Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H. | Deposit date: | 2019-07-30 | Release date: | 2020-04-15 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Action of a minimal contractile bactericidal nanomachine. Nature, 580, 2020
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