7BJV

Crystal structure of the ligand-binding domains of the heterodimer EcR/USP bound to the synthetic agonist BYI09181

Summary for 7BJV

Entry DOI	10.2210/pdb7bjv/pdb
Descriptor	Ultraspiracle protein, Ecdysone Receptor, L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE, ... (7 entities in total)
Functional Keywords	nuclear receptor, ligand-binding domain, ecdysone receptor, dibenzoylhydrazine, transcription
Biological source	Heliothis virescens (Tobacco budworm moth) More
Total number of polymer chains	6
Total formula weight	184401.38
Authors	Browning, C.,McEwen, A.G.,Billas, I.M.L. (deposition date: 2021-01-14, release date: 2021-04-07, Last modification date: 2024-01-31)
Primary citation	Browning, C.,McEwen, A.G.,Mori, K.,Yokoi, T.,Moras, D.,Nakagawa, Y.,Billas, I.M.L. Nonsteroidal ecdysone receptor agonists use a water channel for binding to the ecdysone receptor complex EcR/USP. J Pestic Sci, 46:88-100, 2021 Cited by PubMed: 33746550 DOI: 10.1584/jpestics.D20-095 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.05 Å)

Structure validation