7BJV
Crystal structure of the ligand-binding domains of the heterodimer EcR/USP bound to the synthetic agonist BYI09181
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Ultraspiracle protein | polymer | 263 | 29951.8 | 3 | UniProt (A0A2A4K9Z3) Pfam (PF00104) | Heliothis virescens (Tobacco budworm moth) | |
| 2 | D, E, F (D, E, F) | Ecdysone Receptor | polymer | 266 | 30319.8 | 3 | Pfam (PF00104) UniProt (by SIFTS) (O18473) | Heliothis virescens (Tobacco budworm moth) | |
| 3 | G, H, I (A, B, C) | L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE | non-polymer | 709.9 | 3 | Chemie (EPH) | |||
| 4 | J, L, N (D, E, F) | ~{N}-~{tert}-butyl-2-methoxy-~{N}'-(3-methoxy-2-methyl-phenyl)carbonyl-pyridine-3-carbohydrazide | non-polymer | 371.4 | 3 | Chemie (U0H) | |||
| 5 | K (D) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | M, O, P (E, F) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 7 | Q, R, S, T, U... (A, B, C, D, E...) | water | water | 18.0 | 92 | Chemie (HOH) |
Sequence modifications
A, B, C: 205 - 466 (UniProt: A0A2A4K9Z3)
| PDB | External Database | Details |
|---|---|---|
| Met 204 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 180814.6 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 3586.8 | |
| All* | Total formula weight | 184401.4 |
