7BJU

Crystal structure of the ligand-binding domains of the heterodimer EcR/USP bound to the synthetic agonist BYI08346

Summary for 7BJU

• Entry DOI: 10.2210/pdb7bju/pdb
• Descriptor: Ultraspiracle Protein, Ecdysone Receptor, L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE, ... (9 entities in total)
• Functional Keywords: nuclear receptor, ligand-binding domain, ecdysone receptor, dibenzoylhydrazine, transcription
• Biological source: Heliothis virescens (Tobacco budworm moth); More
• Total number of polymer chains: 2
• Total formula weight: 62058.42

Authors

Browning, C.,McEwen, A.G.,Billas, I.M.L. (deposition date: 2021-01-14, release date: 2021-04-07, Last modification date: 2024-01-31)

• Primary citation: Browning, C.,McEwen, A.G.,Mori, K.,Yokoi, T.,Moras, D.,Nakagawa, Y.,Billas, I.M.L.; Nonsteroidal ecdysone receptor agonists use a water channel for binding to the ecdysone receptor complex EcR/USP.; J Pestic Sci, 46:88-100, 2021; PubMed: 33746550; DOI: 10.1584/jpestics.D20-095

Experimental method

X-RAY DIFFRACTION (2.85 Å)