7BJU
Crystal structure of the ligand-binding domains of the heterodimer EcR/USP bound to the synthetic agonist BYI08346
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ultraspiracle Protein | polymer | 263 | 29951.8 | 1 | UniProt (A0A2A4K9Z3) Pfam (PF00104) | Heliothis virescens (Tobacco budworm moth) | |
| 2 | B (D) | Ecdysone Receptor | polymer | 266 | 30319.8 | 1 | Pfam (PF00104) UniProt (by SIFTS) (O18473) | Heliothis virescens (Tobacco budworm moth) | |
| 3 | C (A) | L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE | non-polymer | 709.9 | 1 | Chemie (EPH) | |||
| 4 | D (D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | E (D) | N-[2-(2-chlorophenyl)-4-methyl-5-(1-methylethyl)-1H-imidazol-1-yl]-5-methyl-2,3-dihydro-1,4-benzodioxine-6-carboxamide | non-polymer | 425.9 | 1 | Chemie (834) | |||
| 6 | F (D) | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL | non-polymer | 370.4 | 1 | Chemie (PE8) | |||
| 7 | G (D) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 8 | H (D) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 9 | I, J (A, D) | water | water | 18.0 | 88 | Chemie (HOH) |
Sequence modifications
A: 205 - 466 (UniProt: A0A2A4K9Z3)
| PDB | External Database | Details |
|---|---|---|
| Met 204 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60271.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1786.9 | |
| All* | Total formula weight | 62058.4 |
