7AX8
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7AXE
| Crystal structure of the hPXR-LBD in complex with oxadiazon | 分子名称: | GLYCEROL, ISOPROPYL ALCOHOL, Nuclear receptor subfamily 1 group I member 2, ... | 著者 | Harrus, D, Delfosse, V, Bourguet, W. | 登録日 | 2020-11-09 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures. Proc.Natl.Acad.Sci.USA, 118, 2021
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7AXD
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7AXL
| Crystal structure of the hPXR-LBD in complex with estradiol and heptachlor endo-epoxide | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ESTRADIOL, Nuclear receptor subfamily 1 group I member 2, ... | 著者 | Delfosse, V, Granell, M, Blanc, P, Bourguet, W. | 登録日 | 2020-11-09 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures. Proc.Natl.Acad.Sci.USA, 118, 2021
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7AXK
| Crystal structure of the hPXR-LBD in complex with estradiol and endosulfan | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ESTRADIOL, GLYCEROL, ... | 著者 | Huet, T, Delfosse, V, Bourguet, W. | 登録日 | 2020-11-09 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures. Proc.Natl.Acad.Sci.USA, 118, 2021
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7AXI
| Crystal structure of the hPXR-LBD in complex with estradiol and cis-chlordane | 分子名称: | (+)cis-chlordane, (-)cis-chlordane, (4S)-2-METHYL-2,4-PENTANEDIOL, ... | 著者 | Huet, T, Delfosse, V, Bourguet, W. | 登録日 | 2020-11-09 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures. Proc.Natl.Acad.Sci.USA, 118, 2021
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7AXA
| Crystal structure of the hPXR-LBD in complex with clotrimazole | 分子名称: | 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE, Nuclear receptor subfamily 1 group I member 2 | 著者 | Delfosse, V, Granell, M, Blanc, P, Bourguet, W. | 登録日 | 2020-11-09 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures. Proc.Natl.Acad.Sci.USA, 118, 2021
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7AXF
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4X1G
| Crystal structure of the hPXR-LBD in complex with the synthetic estrogen 17alpha-ethinylestradiol and the pesticide trans-nonachlor | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Ethinyl estradiol, ISOPROPYL ALCOHOL, ... | 著者 | Delfosse, V, Huet, T, Bourguet, W. | 登録日 | 2014-11-24 | 公開日 | 2015-09-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Synergistic activation of human pregnane X receptor by binary cocktails of pharmaceutical and environmental compounds. Nat Commun, 6, 2015
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4X1F
| Crystal structure of the hPXR-LBD in complex with the synthetic estrogen 17alpha-ethinylestradiol | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Ethinyl estradiol, Nuclear receptor subfamily 1 group I member 2 | 著者 | Delfosse, V, Huet, T, Bourguet, W. | 登録日 | 2014-11-24 | 公開日 | 2015-09-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Synergistic activation of human pregnane X receptor by binary cocktails of pharmaceutical and environmental compounds. Nat Commun, 6, 2015
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4XAO
| Crystal structure of the hPXR-LBD obtained in presence of the pesticide trans-nonachlor | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ISOPROPYL ALCOHOL, Nuclear receptor subfamily 1 group I member 2 | 著者 | Delfosse, V, Huet, T, Bourguet, W. | 登録日 | 2014-12-15 | 公開日 | 2015-09-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Synergistic activation of human pregnane X receptor by binary cocktails of pharmaceutical and environmental compounds. Nat Commun, 6, 2015
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4MG5
| Crystal structure of hERa-LBD (Y537S) in complex with chlordecone | 分子名称: | Estrogen receptor, GLYCEROL, Nuclear receptor coactivator 1, ... | 著者 | Delfosse, V, Grimaldi, M, Bourguet, W. | 登録日 | 2013-08-28 | 公開日 | 2014-09-03 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural and functional profiling of environmental ligands for estrogen receptors. Environ.Health Perspect., 122, 2014
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6I61
| Crystal structure of human ERRg LBD in complex with bisphenol-B | 分子名称: | 1,2-ETHANEDIOL, Estrogen-related receptor gamma, GLYCEROL, ... | 著者 | Delfosse, V, Blanc, P, Bourguet, W. | 登録日 | 2018-11-15 | 公開日 | 2019-07-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Insights into the activation mechanism of human estrogen-related receptor gamma by environmental endocrine disruptors. Cell.Mol.Life Sci., 76, 2019
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6HJ2
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6I67
| Crystal structure of human ERRg LBD in complex with tetrahydro-2-naphtol | 分子名称: | 5,6,7,8-tetrahydronaphthalen-2-ol, Estrogen-related receptor gamma, GLYCEROL | 著者 | Delfosse, V, Blanc, P, Bourguet, W. | 登録日 | 2018-11-15 | 公開日 | 2019-07-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Insights into the activation mechanism of human estrogen-related receptor gamma by environmental endocrine disruptors. Cell.Mol.Life Sci., 76, 2019
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6I65
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6I63
| Crystal structure of human ERRg LBD in complex with bisphenol-A | 分子名称: | 4,4'-PROPANE-2,2-DIYLDIPHENOL, Estrogen-related receptor gamma | 著者 | Delfosse, V, Blanc, P, Bourguet, W. | 登録日 | 2018-11-15 | 公開日 | 2019-07-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.229 Å) | 主引用文献 | Insights into the activation mechanism of human estrogen-related receptor gamma by environmental endocrine disruptors. Cell.Mol.Life Sci., 76, 2019
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6I64
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6I66
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6I62
| Crystal structure of human ERRg LBD in complex with HPTE | 分子名称: | 4,4'-(2,2,2-trichloroethane-1,1-diyl)diphenol, Estrogen-related receptor gamma | 著者 | Delfosse, V, Blanc, P, Bourguet, W. | 登録日 | 2018-11-15 | 公開日 | 2019-07-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Insights into the activation mechanism of human estrogen-related receptor gamma by environmental endocrine disruptors. Cell.Mol.Life Sci., 76, 2019
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3SPW
| Structure of Osh4p/Kes1p in complex with phosphatidylinositol 4-phosphate | 分子名称: | (2R)-1-(heptadecanoyloxy)-3-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, Protein KES1 | 著者 | Delfosse, V, de Saint-Jean, M, Douguet, D, Antonny, B, Drin, G, Bourguet, W. | 登録日 | 2011-07-04 | 公開日 | 2011-11-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers. J.Cell Biol., 195, 2011
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4MG9
| Crystal structure of hERa-LBD (Y537S) in complex with butylparaben | 分子名称: | Estrogen receptor, GLYCEROL, Nuclear receptor coactivator 1, ... | 著者 | Delfosse, V, Grimaldi, M, Bourguet, W. | 登録日 | 2013-08-28 | 公開日 | 2014-09-03 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural and functional profiling of environmental ligands for estrogen receptors. Environ.Health Perspect., 122, 2014
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4MG6
| Crystal structure of hERa-LBD (Y537S) in complex with benzylbutylphtalate | 分子名称: | Estrogen receptor, GLYCEROL, Nuclear receptor coactivator 1, ... | 著者 | Delfosse, V, Grimaldi, M, Bourguet, W. | 登録日 | 2013-08-28 | 公開日 | 2014-09-03 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural and functional profiling of environmental ligands for estrogen receptors. Environ.Health Perspect., 122, 2014
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4MGC
| Crystal structure of hERa-LBD (Y537S) in complex with benzophenone-2 | 分子名称: | Estrogen receptor, GLYCEROL, Nuclear receptor coactivator 1, ... | 著者 | Delfosse, V, Grimaldi, M, Bourguet, W. | 登録日 | 2013-08-28 | 公開日 | 2014-09-03 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural and functional profiling of environmental ligands for estrogen receptors. Environ.Health Perspect., 122, 2014
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4MGA
| Crystal structure of hERa-LBD (Y537S) in complex with 4-tert-octylphenol | 分子名称: | 4-(2,4,4-trimethylpentan-2-yl)phenol, Estrogen receptor, Nuclear receptor coactivator 1 | 著者 | Delfosse, V, Grimaldi, M, Bourguet, W. | 登録日 | 2013-08-28 | 公開日 | 2014-09-03 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and functional profiling of environmental ligands for estrogen receptors. Environ.Health Perspect., 122, 2014
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