6I62
Crystal structure of human ERRg LBD in complex with HPTE
Summary for 6I62
| Entry DOI | 10.2210/pdb6i62/pdb |
| Related | 6I61 |
| Descriptor | Estrogen-related receptor gamma, 4,4'-(2,2,2-trichloroethane-1,1-diyl)diphenol (3 entities in total) |
| Functional Keywords | transcription factor nuclear receptor endocrine disruptor, nuclear protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 27194.90 |
| Authors | Delfosse, V.,Blanc, P.,Bourguet, W. (deposition date: 2018-11-15, release date: 2019-07-03, Last modification date: 2024-01-24) |
| Primary citation | Thouennon, E.,Delfosse, V.,Bailly, R.,Blanc, P.,Boulahtouf, A.,Grimaldi, M.,Barducci, A.,Bourguet, W.,Balaguer, P. Insights into the activation mechanism of human estrogen-related receptor gamma by environmental endocrine disruptors. Cell.Mol.Life Sci., 76:4769-4781, 2019 Cited by PubMed: 31127318DOI: 10.1007/s00018-019-03129-x PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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