6I64

Crystal structure of human ERRg LBD in complex with bisphenol-E

Summary for 6I64

Entry DOI	10.2210/pdb6i64/pdb
Descriptor	Estrogen-related receptor gamma, 4-[1-(4-hydroxyphenyl)ethyl]phenol, GLYCEROL, ... (4 entities in total)
Functional Keywords	transcription factor nuclear receptor endocrine disruptor, nuclear protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	27791.35
Authors	Delfosse, V.,Blanc, P.,Bourguet, W. (deposition date: 2018-11-15, release date: 2019-07-03, Last modification date: 2024-01-24)
Primary citation	Thouennon, E.,Delfosse, V.,Bailly, R.,Blanc, P.,Boulahtouf, A.,Grimaldi, M.,Barducci, A.,Bourguet, W.,Balaguer, P. Insights into the activation mechanism of human estrogen-related receptor gamma by environmental endocrine disruptors. Cell.Mol.Life Sci., 76:4769-4781, 2019 Cited by PubMed: 31127318 DOI: 10.1007/s00018-019-03129-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.91 Å)

Structure validation